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Younger, healthier skin starts at the cellular level

Meet OS-01, the first peptide proven to target a root cause of skin agingβ€”cellular senescence.01

OneSkin

The real proof? It’s in the numbers.

9

years of research

900

peptides screened

18

patents & publications

9000

5-Star Reviews

OUR BREAKTHROUGH PEPTIDE

OS-01: the new standard in peptide technology

Think of OS-01 as a reset button for your skin, helping clear away the senescent cells that cause wrinkles, hyperpigmentation, and crepiness. As the first peptide scientifically proven to reduce cellular senescence in the skin, OS-01 does what other peptides can’t.01

DAILY ESSENTIALS

The 5-minute skin health routine

Frequently Asked Questions

OneSkin

01Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age Β  and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
02Zonari A.,et al.Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation.J Cosmet Dermatol.2024; 23: 2135-2144. doi:10.1111/jocd.16242
03Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more atoneskin.co/claims
04Zonari, A.,et al.Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging.Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

OneSkin
PHILANTHROPY

Propelled by a shared mission to
change the way humans experience aging

We donate a portion of sales to the Aging Forward (formerly Shepherd's Center of America), which provides enriching opportunities for lifelong learning, volunteer service, healthy living, and community connections - all of the things that give life meaning.