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FACE, EYE + LIP TRIO

4.5
4.5 out of 5
4.5 out of 5
(1,022)

Hydrating face, eye, and lip duo that smooths + protects.

  • Age-Reversal Peptide
  • Smoothing
  • UV Protection
  • Fragrance Free
Set of skincare products from ONE SKIN on a light beige background
Three cosmetic products labeled 'OS-01 Face Moisturizer', 'OS-01 Eye Cream', and 'Bare Blush Lip Shield' on a white background.
Close-up of a woman's face with OS-01 Face Moisturizer applied, showing reduced fine lines and wrinkles.
Woman applying a lip product with text about immediate hydration on a close-up of her face.
Close-up of a woman's face with eye cream application showing improved elasticity.
Skincare products with user testimonials on a white background
Two skincare bottles with 'ONE SKIN' branding on a reflective surface.
Set of skincare products from ONE SKIN on a light beige background
Three cosmetic products labeled 'OS-01 Face Moisturizer', 'OS-01 Eye Cream', and 'Bare Blush Lip Shield' on a white background.
Close-up of a woman's face with OS-01 Face Moisturizer applied, showing reduced fine lines and wrinkles.
Woman applying a lip product with text about immediate hydration on a close-up of her face.
Close-up of a woman's face with eye cream application showing improved elasticity.
Skincare products with user testimonials on a white background
Two skincare bottles with 'ONE SKIN' branding on a reflective surface.

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  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

Details
  • Hydrate, smooth, and protect skin and lips from visible signs of aging with a trio powered by our proprietary OS-01 Senescence-Blocking Peptide™
  • OS-01 EYE CREAM improves elasticity and firmness while smoothing the appearance of fine lines and wrinkles1,2
  • OS-01 FACE MOISTURIZER visibly smooths and softens texture, evens skin tone, and strengthens skin's protective barrier2
  • OS-01 LIP SPF 15 protects lips from UV damage while delivering lightweight hydration
  • Lightweight textures instantly absorb into skin with no residue
Ingredients

Formulated without
Non-comedogenic and formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.

OS-01 FACE MOISTURIZER Ingredients
Water (Aqua), Glycerin, Sorbitan Olivate, Helianthus Annuus (Sunflower) Seed Oil, Squalane, Cetearyl Olivate, Carapa Guianensis Seed Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba Seed Oil, Rosa Canina Fruit Oil, Prunus Domestica Seed Oil, Calycophyllum Spruceanum Bark Extract, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

OS-01 EYE CREAM Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate.
*OS-01 Peptide


OS-01 LIP SPF 15 Ingredients

Active Ingredient
 Zinc Oxide 5.5%

Inactive Ingredients
Aqua (Water), Beta-Sitosterol, Bisabolol, Butylene/Ethylene/Styrene Copolymer, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Caprylyl/Capryl Glucoside, Centella Asiatica Extract, Copernicia Cerifera Cera (Carnauba) Wax, Decapeptide-52*, Dipalmitoyl Hydroxyproline, Ectoin, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Ethylhexylglycerin, Garcinia Indica Seed Butter, Glucomannan, Glycerin, Glyceryl Dioleate, Glyceryl Oleate, Helianthus Annuus (Sunflower) Seed Oil, Hippophae Rhamnoides (Sea Buckthorn) Seed Oil, Isostearic Acid, Lactic Acid, Lecithin, Oleic Acid, Palmitic Acid, Palmitoyl Tripeptide-1, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Propanediol, Simmondsia Chinensis (Jojoba) Seed Oil, Sodium Hyaluronate, Sorbitan Isostearate, Squalene, Tetrahexyldecyl Ascorbate, Tocopherol, Tocopheryl Acetate, Tribehenin, Trihydroxystearin.

*OS-01 Peptide

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn

  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.

  • Do not use on damaged or broken skin.

  • Stop use and ask a doctor if rash occurs.

  • Keep out of reach of children.

This set includes

Clear bottle with black pump and 'One Skin' label on a light beige background

STEP 1

OS-01 EYE CREAM

Nourishing hydration that improves elasticity + firmness.

Size

20 mL / .67 fl oz

How to use

Gently tap 1⁄2-1 pump around each eye.

Skincare bottle labeled 'One Skin' on a beige background

STEP 2

OS-01 FACE MOISTURIZER

Lightweight hydration clinically shown to firm and smooth skin.

Size

50 mL / 1.7 fl oz

How to use

Gently massage 1-2 pumps into the face, neck, and chest.

Tube of One Skin sunscreen on a light beige background

STEP 3

OS-01 LIP SPF 15

Hydrating SPF lip balm that hydrates, protects, and restores.

Size

12 mL / 0.41 fl oz

How to use

Apply generously to lips before sun exposure. Reapply throughout the day, especially after eating, drinking, swimming, sweating, or towel drying.

OS-01 Peptide logo featuring a solid orange square on the left, followed by the text 'OS-01' in black and 'PEPTIDE' in bold black letters, with a small trademark symbol.

Engineered to reverse skin’s visible biological age.4

Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid and barrier strength. The result: skin that looks, feels, and acts younger over time.

Explore the science →

Clinically validated results that build over time

Before-and-after comparison of under-eye dark circles on a person's face, with the top labeled BEFORE and the bottom labeled AFTER 12 WEEKS. The image shows close-up views of the left eye area with a dotted circle highlighting the skin region.

95%

reported smoother-looking and more even-toned skin after 4 weeks1

Before-and-after comparison of a person's eye area showing skin texture and wrinkles around the eye, with text reading 'BEFORE' and 'AFTER 12 WEEKS' on a beige sidebar.

95%

reported improved overall appearance after 12 weeks1

Before-and-after comparison of a closed eye showing skin texture and wrinkles around the eyelid, with dotted white outlines highlighting the treated area. The top panel is labeled BEFORE and the bottom panel is labeled AFTER 12 WEEKS.

86%

had improved elasticity after 12 weeks1

WEEK 1

Instant hydration you can feel 

  • OS-01 Peptide™  gets to work reversing the visible effects of senescent (dysfunctional, aging) cells
  • Supporting ingredients instantly hydrate and smooth
  • Caffeine visibly stimulates circulation
Month 1

Visibly smoother, firmer, more-even-toned skin

  • +20% boost in hydration1
  • 95% observed visibly smoother texture and a more even tone1
  • 86% had improved elasticity after 12 weeks1
Month 12

Visibly healthier, firmer skin that looks, feels + acts younger

  • +27% improvement in visible firmness2
  • +29% improvement in visible elasticity2
  • -18% reduced appearance of fine lines and wrinkles 
  • +25% improved radiance2 
  • 95% saw improvements in general appearance2

Key ingredients

A thick, creamy white swatch of cosmetic cream or lotion on a solid black background.
OS-01 Peptide™

Proven to reverse skin's visible biological age by reversing the visible effects of senescent (dysfunctional, aging) cells.

Moringa oleifera seed extract

Protects skin cells against environmental pollutants that can trigger visible skin aging.

Biomimetic vegan collagen

This biodesigned vegan collagen peptide visibly boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to reach the deeper layers. 

Fucus vesiculosus algae extract

Helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.

All Ingredients

Formulated without
Non-comedogenic and formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.


OS-01 FACE MOISTURIZER Ingredients
Water (Aqua), Glycerin, Sorbitan Olivate, Helianthus Annuus (Sunflower) Seed Oil, Squalane, Cetearyl Olivate, Carapa Guianensis Seed Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba Seed Oil, Rosa Canina Fruit Oil, Prunus Domestica Seed Oil, Calycophyllum Spruceanum Bark Extract, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.


OS-01 EYE CREAM Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate.
*OS-01 Peptide




OS-01 LIP SPF 15 Ingredients


Active Ingredient
 Zinc Oxide 5.5%


Inactive Ingredients
Aqua (Water), Beta-Sitosterol, Bisabolol, Butylene/Ethylene/Styrene Copolymer, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Caprylyl/Capryl Glucoside, Centella Asiatica Extract, Copernicia Cerifera Cera (Carnauba) Wax, Decapeptide-52*, Dipalmitoyl Hydroxyproline, Ectoin, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Ethylhexylglycerin, Garcinia Indica Seed Butter, Glucomannan, Glycerin, Glyceryl Dioleate, Glyceryl Oleate, Helianthus Annuus (Sunflower) Seed Oil, Hippophae Rhamnoides (Sea Buckthorn) Seed Oil, Isostearic Acid, Lactic Acid, Lecithin, Oleic Acid, Palmitic Acid, Palmitoyl Tripeptide-1, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Propanediol, Simmondsia Chinensis (Jojoba) Seed Oil, Sodium Hyaluronate, Sorbitan Isostearate, Squalene, Tetrahexyldecyl Ascorbate, Tocopherol, Tocopheryl Acetate, Tribehenin, Trihydroxystearin.


*OS-01 Peptide


Drug Facts


Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen
















Uses


  • Helps prevent sunburn




  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings


  • For external use only.




  • Do not use on damaged or broken skin.




  • Stop use and ask a doctor if rash occurs.




  • Keep out of reach of children.

OneSkin Longevity Protocol

FACE, EYE + LIP TRIO

Write a Review (Opens in a new window)
1,022 reviews
  • D
    Diane
    Reviewing
    OS-01 FACE MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    5 minutes ago
    5 Stars

    I like this line of skin care, it is smooth on my skin and doesn’t smell strong perfume. My skin looks fresh and healthy

    Was this helpful?
  • D
    Debra
    Reviewing
    OS-01 FACE MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    5 Stars

    Love the body and face!

    Was this helpful?
  • CW
    Candice W.
    Verified Buyer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Best eye cream

    LOVE LOVE LOVE!!! I have tried a million creams, balms and gels always searching for the holy grail. I think this is it! Feels amazing going on and is absorbed nicely so makeup doesn’t cake. Great product!!

    Was this helpful?
  • MQ
    Maureen Q.
    Verified Buyer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    Happy eyelids!

    My upper eyelids are lifting!

    Was this helpful?
  • AH
    Allison H.
    Verified Buyer
    Reviewing
    OS-01 FACE MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    Face Moisturizer

    So far so good! My face still gets oily at 50 years old, but this face moisturizer does not make your face feel greasy or oily at all. Also works well underneath makeup.

    Was this helpful?
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Citations

  1. Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025.) 
  2. Based on a third-party 12-month clinical study with 23 participants aged 47–60. 
  3. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)
  4. Visible biological age defined as signs of aging such as smoothness and barrier strength. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)