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The complete longevity trio for your most exposed skin - face, eyes, and lips.



  • Protect against 3 main drivers of lip skin aging with Bare Blush Lip Shield SPF 15+

  • Boosts visible radiance, firmness, and barrier resilience with OS-01 FACE Moisturizer

  • Strengthen delicate eye skin and boost visible elasticity with OS-01 EYE Cream

  • Dermatologist tested, fragrance-free, suitable for sensitive skin

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  • Skincare bottle labeled 'One Skin' on a beige backgroundOS-01 FACE MOISTURIZER
  • Clear bottle with black pump and 'One Skin' label on a light beige backgroundOS-01 EYE CREAM
  • Accepted National Eczema Association logo
  • Leaping bunny certified logo

OneSkin

Ingredients that complement the OS-01 PeptideTM

Hyaluronic acid
Supports hydration, plumpness, and elasticity in both facial skin and lips.

Vitamin E
A potent antioxidant that helps neutralize oxidative stress and supports daily repair from UV and environmental exposure.

Barrier-supporting lipids & oil
A tailored blend of biomimetic lipids and nourishing oils strengthens the skin barrier across facial skin, eye skin, and lips, helping improve comfort, softness, and long-term resilience.

How it works

Powered by the OS-01 Senescence Peptide™

Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.

FACE, EYE + LIP TRIO

4.5
Rated 4.5 out of 5 stars
Based on 962 reviews
Total 5 star reviews: 733 Total 4 star reviews: 111 Total 3 star reviews: 45 Total 2 star reviews: 35 Total 1 star reviews: 38
88%would recommend these products
962 reviews
  • AS
    Alanna S.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    Love it!

    Love the neutral color and how it doesn't dry my lips out like so many other types of lip gloss. It's the perfect texture and isn't sticky.

  • M'
    Marilyn '. P.
    Verified Buyer
    Reviewing
    FACE, EYE + LIP TRIO
    I recommend this product
    Rated 5 out of 5 stars
    5 hours ago
    FAB Face👩🏻 Eye 👁️Lip 💋 TRIO!!!!!!

    Face👩🏻 Eye 👁️Lip 💋Trio

    Already hooked on OneSkin products, this trio is the perfect solution to replenish Face and Eye cream AND to test Bare Blush Lip SPF. Indeed a step up from the original clear one which I have used since it was first introduced. Bare Blush has the same luxurious shine and moisturizing, yet not heavy, feel along with SPF protection and a natural look for my skin tone. Brava!

    Love-Love-Love OneSkin!!!!!!!!!!

  • CR
    Chante R.
    Verified Reviewer
    Reviewing
    OS-01 FACE MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    Best Facial Rejuvenation EVER

    I stopped retinol entirely and have never been happier. My skin health has reversed and my under eye bags have been conquered! I look younger than I had in years before starting One Skin. Thank you! It is truly great for my skin health.

    OneSkin
    3 days ago

    Hi Chante! Thank you so much for your incredible 5-star feedback about OS-01 FACE! We're absolutely thrilled to hear that you consider it the best facial rejuvenation ever and that you're experiencing such amazing transformative results - that kind of enthusiastic response really means the world to all of us at OneSkin!

    It's wonderful that you've found such success moving away from retinol and discovering how OS-01 FACE works for your skin! The fact that you're seeing your skin health reverse, conquering those under eye bags, and looking younger than you have in years shows exactly how our science-backed OS-01 peptide works at the cellular level to target senescence and support your skin's natural renewal processes in a gentler yet powerful way.

    Your experience demonstrates the beauty of finding the right approach for your individual skin - sometimes stepping away from traditional actives like retinol and embracing innovative peptide technology can create exactly the kind of dramatic improvements you're describing. The visible age-reversing results you're seeing are exactly what we hoped you'd experience with consistent use!

    Thank you for taking the time to share such encouraging feedback about your OS-01 FACE experience - your 5-star review and enthusiasm about looking younger truly means so much to us!

  • MG
    Myra G.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 4 out of 5 stars
    3 days ago
    Love

    This feels so good on and the color is perfect! I love when I need it because I’m going outside during the day.

    OneSkin
    3 days ago

    Hi Myra! Thank you so much for your wonderful 4-star feedback about OS-01 LIP SHIELD SPF 15+! We're absolutely thrilled to hear that you love how it feels on your lips and that the color is perfect for you - that kind of positive daily experience really means the world to all of us at OneSkin!

    It's fantastic that you're reaching for it whenever you're heading outside during the day! The fact that it's become your go-to for daytime protection shows exactly how our science-backed approach to lip care can fit seamlessly into your routine while providing that essential SPF protection your lips need from UV exposure.

    Your insights about both the luxurious feel and the perfect color match are exactly the kind of thoughtful feedback that shows how OS-01 LIP SHIELD delivers on both protection and that everyday wearability you're looking for!

    Thank you for taking the time to share such encouraging feedback about your OS-01 LIP SHIELD SPF 15+ experience - your 4-star review truly means so much to us!

  • SB
    Suzanne B.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 4 out of 5 stars
    4 days ago
    Great lip balm

    Wonderful lip balm. Only 4 stars as I am not overly keen on the colour. I will buy again but would get the uncoloured option.

    OneSkin
    4 days ago

    Hi Suzanne!

    Thank you so much for taking the time to share your feedback about OS-01 LIP SHIELD SPF 15+ — we're delighted to hear that you're loving the lip balm quality! That means the world to us.

    We completely understand your thoughts on the color, and we're so glad you mentioned the untinted option! You're absolutely right that OS-01 LIP SHIELD comes in both tinted and untinted versions, so you can get all the same OS-01 peptide benefits, SPF 15+ mineral broad spectrum protection, and nourishing ingredients without any color at all. It sounds like that would be the perfect fit for your preferences!

    We really appreciate your honest feedback about both what's working wonderfully and what could be better for you. Knowing that customers love the formula but have different color preferences helps us understand how our range is meeting different needs.

    Thank you for choosing OneSkin!

Full ingredient list

OS-01 FACE ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

OS-01 EYE Ingredients

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.

OS-01 LIP SHIELD SPF 15+ BARE BLUSH ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive ingredients: Simmondsia Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae rhamnoides (Sea Buckthorn) Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Lactic Acid, Octyldodecanol, Sorbitan Oleate, Alumina, Magnesium Oxide, Palmitic Acid, Iron oxides (CI 77491, CI 77492, CI 77499), Titanium Dioxide (CI 77891), Red 33 Lake (CI 17200), Red 7 Lake (CI 15850).

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

Citations

01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1