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OS-01 LIP SPF 15

4.5
4.5 out of 5
4.5 out of 5
(409)

Hydrating SPF lip balm that hydrates, protects, and restores.

Size: 12 mL / 0.41 fl oz

  • Age-Reversal Peptide
  • Broad Spectrum
  • Antioxidant Protection
  • Fragrance Free
Tube of One Skin sunscreen on a light beige background
White tube of One Skin lip spf on a light beige background
Woman with immediate hydration text on a beige background
Close-up of a beige product texture on a white background
Two skincare products with 'ONE SKIN' branding on an orange background
Close-up of a person's face with a focus on lips, featuring text about mineral broad-spectrum protection.
Close-up of a woman's face with text indicating an increase in elastin for firm, bouncy lips.
Sculptural object with a spherical beige top and metallic silver base on a gray background
Close-up of a peach-colored lip gloss on a white background
Close-up of a person's face with a focus on the lips, showing immediate hydration with text overlay.
Three cosmetic applicators with text describing their functions on a white background
Woman using a lip balm with a close-up focus on her lips and the product.
Lip balm tube with a swatch of pink lip balm on a metallic surface
Tube of One Skin sunscreen on a light beige background
White tube of One Skin lip spf on a light beige background
Woman with immediate hydration text on a beige background
Close-up of a beige product texture on a white background
Two skincare products with 'ONE SKIN' branding on an orange background
Close-up of a person's face with a focus on lips, featuring text about mineral broad-spectrum protection.
Close-up of a woman's face with text indicating an increase in elastin for firm, bouncy lips.
Sculptural object with a spherical beige top and metallic silver base on a gray background
Close-up of a peach-colored lip gloss on a white background
Close-up of a person's face with a focus on the lips, showing immediate hydration with text overlay.
Three cosmetic applicators with text describing their functions on a white background
Woman using a lip balm with a close-up focus on her lips and the product.
Lip balm tube with a swatch of pink lip balm on a metallic surface

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  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

Details
  • Our proprietary OS-01 Senescence-Blocking Peptide™ visibly slows cellular skin aging, resulting in skin that feels and acts younger over time
  • Hydrates and protects lips from UV-induced damage
  • Enriched with nourishing oils and antioxidants to keep lips smooth, supple, and comfortable
  • Dermatologist tested, fragrance free, and suitable for sensitive skin
Ingredients

Formulated without
OS-01 LIP SPF is non-comedogenic and formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.

Active Ingredient
 Zinc Oxide 5.5%

Inactive Ingredients
Aqua (Water), Beta-Sitosterol, Bisabolol, Butylene/Ethylene/Styrene Copolymer, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Caprylyl/Capryl Glucoside, Centella Asiatica Extract, Copernicia Cerifera Cera (Carnauba) Wax, Decapeptide-52*, Dipalmitoyl Hydroxyproline, Ectoin, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Ethylhexylglycerin, Garcinia Indica Seed Butter, Glucomannan, Glycerin, Glyceryl Dioleate, Glyceryl Oleate, Helianthus Annuus (Sunflower) Seed Oil, Hippophae Rhamnoides (Sea Buckthorn) Seed Oil, Isostearic Acid, Lactic Acid, Lecithin, Oleic Acid, Palmitic Acid, Palmitoyl Tripeptide-1, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Propanediol, Simmondsia Chinensis (Jojoba) Seed Oil, Sodium Hyaluronate, Sorbitan Isostearate, Squalene, Tetrahexyldecyl Ascorbate, Tocopherol, Tocopheryl Acetate, Tribehenin, Trihydroxystearin.

*OS-01 Peptide

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn

  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.

  • Do not use on damaged or broken skin.

  • Stop use and ask a doctor if rash occurs.

  • Keep out of reach of children.
How to use

Apply generously to lips before sun exposure. Reapply throughout the day, especially after eating, drinking, swimming, sweating, or towel drying.

Complete the Protocol

OS-01 Peptide logo featuring a solid orange square on the left, followed by the text 'OS-01' in black and 'PEPTIDE' in bold black letters, with a small trademark symbol.

Engineered to reverse skin’s visible biological age.1

Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid and barrier strength. The result: skin that looks, feels, and acts younger over time.

Explore the science →

Key ingredients

Blush swipe of cosmetic product on a black background
OS-01 Peptide™

Proven to reverse skin's visible biological age by reversing the visible effects of senescent (dysfunctional, aging) cells.

Non-nano zinc oxide

Protects against UV aging and damage with mineral broad spectrum SPF 15+ defense.

Bisabolol

A chamomile-derived antioxidant that soothes irritation, calms signs of inflammation, and enhances ingredient absorption.

Vitamin E

A potent antioxidant that helps neutralize oxidative stress and supports daily repair from UV and environmental exposure.

Hyaluronic acid

A highly bioavailable form that delivers immediate hydration and long-lasting moisture retention.

All Ingredients

Formulated without
OS-01 LIP SPF is non-comedogenic and formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.


Active Ingredient
 Zinc Oxide 5.5%


Inactive Ingredients
Aqua (Water), Beta-Sitosterol, Bisabolol, Butylene/Ethylene/Styrene Copolymer, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Caprylyl/Capryl Glucoside, Centella Asiatica Extract, Copernicia Cerifera Cera (Carnauba) Wax, Decapeptide-52*, Dipalmitoyl Hydroxyproline, Ectoin, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Ethylhexylglycerin, Garcinia Indica Seed Butter, Glucomannan, Glycerin, Glyceryl Dioleate, Glyceryl Oleate, Helianthus Annuus (Sunflower) Seed Oil, Hippophae Rhamnoides (Sea Buckthorn) Seed Oil, Isostearic Acid, Lactic Acid, Lecithin, Oleic Acid, Palmitic Acid, Palmitoyl Tripeptide-1, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Propanediol, Simmondsia Chinensis (Jojoba) Seed Oil, Sodium Hyaluronate, Sorbitan Isostearate, Squalene, Tetrahexyldecyl Ascorbate, Tocopherol, Tocopheryl Acetate, Tribehenin, Trihydroxystearin.


*OS-01 Peptide


Drug Facts


Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen



















Uses


  • Helps prevent sunburn




  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings


  • For external use only.




  • Do not use on damaged or broken skin.




  • Stop use and ask a doctor if rash occurs.




  • Keep out of reach of children.

OneSkin Longevity Protocol

OS-01 LIP SPF 15

Write a Review (Opens in a new window)
409 reviews
  • MC
    Monica C.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 5 out of 5 stars
    17 minutes ago
    Repurchase

    This lip spf feels hydrating and silky, not sticky at all. My lips feel smoother when on. I like the applicator as well. Would recommend to anyone considering purchasing.

    Was this helpful?
    OneSkin
    3 minutes ago

    Hi Monica! Thank you so much for your feedback about our OS-01 LIP SPF 15.

    We're absolutely thrilled to hear that you're loving how hydrating and silky the formula feels, and that it's not sticky at all! It's wonderful that your lips feel smoother when wearing it, and we're so glad you're impressed with the applicator too. We really appreciate you taking the time to share your honest feedback with us, and we're excited that you'd recommend it to others!

  • MC
    Monica C.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 5 out of 5 stars
    22 hours ago
    Great product

    Love this lip spf!! Not sticky, feels great on the lips. I loved it so much I have a few, can’t wait to purchase the tinted one

    Was this helpful?
  • DL
    Debbie L.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Love this!

    Noticed a difference in the lines of my lips not being so noticeable!

    Was this helpful?
  • DB
    Danielle B.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 4 out of 5 stars
    3 days ago
    Great product

    I really like this as a lip gloss! It adds a touch of color while providing SPF without feeling sticky. I wish it lasted in my lips a bit longer … but I will continue to buy!

    Was this helpful?
    OneSkin
    3 days ago

    Hi Danielle! Thank you so much for your wonderful feedback about our OS-01 LIP SPF 15.

    We're so glad to hear that you're loving it as a lip gloss and that you're enjoying the color and SPF protection without the sticky feeling! We really appreciate you taking the time to share your honest feedback with us, and we're thrilled that you'll continue to buy!

  • GW
    gloria W.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    Feels wonderful

    My lips feel moisturized

    Was this helpful?
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Citations

  1. Visible biological age defined as signs of aging such as smoothness and barrier strength. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)