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FACE + LIP DUO

Cellular longevity support for your most exposed skin – face and lips.


  • Protect against 3 main drivers of lip skin aging with Bare Blush Lip Shield SPF 15+

  • Boost hydration, strengthen the skin barrier, and enhance visible elasticity with OS-01 FACE Moisturizer

  • Dermatologist tested, fragrance-free, suitable for sensitive skin

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  • Skincare bottle labeled 'One Skin' on a beige backgroundOS-01 FACE MOISTURIZER
  • Accepted National Eczema Association logo
  • Leaping bunny certified logo

OneSkin

Ingredients that complement the OS-01 PeptideTM


Hyaluronic acid

Supports hydration, plumpness, and elasticity in both facial skin and lips.


Vitamin E

A potent antioxidant that helps neutralize oxidative stress and supports daily repair from UV and environmental exposure.


Barrier-supporting lipids & oil

A tailored blend of biomimetic lipids and nourishing oils strengthens the skin barrier across facial skin, eye skin, and lips, helping improve comfort, softness, and long-term resilience.

How it works

Powered by the OS-01 Senescence Peptide™

Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.

FACE + LIP DUO

4.7
Rated 4.7 out of 5 stars
Based on 3,347 reviews
Total 5 star reviews: 2.8k Total 4 star reviews: 313 Total 3 star reviews: 113 Total 2 star reviews: 41 Total 1 star reviews: 45
94%would recommend these products
3,347 reviews
  • CM
    Christina M.
    Reviewing
    OS-01 LIP SHIELD BARE BLUSH SPF 15+
    Rated 3 out of 5 stars
    14 hours ago
    Please make more colors

    I hope One Skin makes lip shield with a broader range of shades. This blush color is not attractive on darker skin tones. It doesn't look good on the brown-skinned model in the images. Please be more inclusive with this product.

    FWIW, I love the original lip shield, but this tinted version looks disappointing.

    OneSkin
    2 hours ago

    Hi Christina!

    Thank you so much for taking the time to share your thoughtful feedback about the OS-01 LIP SHIELD BARE BLUSH SPF 15+ — we really appreciate you letting us know about your experience and concerns.

    We're so sorry to hear that the current tint isn't working well for darker skin tones, and we completely understand your disappointment about the limited color range. Your feedback about inclusivity is incredibly important to us, and we genuinely appreciate you bringing this to our attention so directly.

    It means so much to us that you love the original OS-01 LIP SPF, and we're grateful that you took the time to try the tinted version despite your concerns. Your honest feedback about both the shade selection and how it looks on different skin tones is something we take very seriously.

    We'd love to connect with you to learn more about what shades would work better and discuss your experience further. Please reach out to support@oneskin.co — your input could really help us improve this product for everyone!

  • PB
    Pamela B.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Feels amazing!

    I LOVE, LOVE, LOVE this product!

  • MO
    Maureen O.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch, Replacement
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    I love that it's refillable!

    I love that it's refillable!

  • K
    Kim
    Reviewing
    OS-01 FACE MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    5 Stars

    Perfect as always. Will not use any ither moisturizer.

  • S
    Stephanie
    Reviewing
    OS-01 FACE MOISTURIZER
    I do not recommend this product
    Rated 2 out of 5 stars
    2 days ago
    2 Stars

    It doesn't absorb into my skin.

Full ingredient list

OS-01 FACE ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

OS-01 LIP SHIELD SPF 15+ BARE BLUSH ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive ingredients: Simmondsia Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae rhamnoides (Sea Buckthorn) Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Lactic Acid, Octyldodecanol, Sorbitan Oleate, Alumina, Magnesium Oxide, Palmitic Acid, Iron oxides (CI 77491, CI 77492, CI 77499), Titanium Dioxide (CI 77891), Red 33 Lake (CI 17200), Red 7 Lake (CI 15850).

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

Citations

01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1