This is a carousel. Use Next and Previous buttons to navigate

This is a carousel. Use Next and Previous buttons to navigate

Subscribe & save 15%

Free shipping on orders over $79.00 USD

OS-01 LIP MASK

4.4
4.4 out of 5
4.4 (306)

7 mL / 0.24 fl oz

OS-01 LIP MASK

Topical Supplement

4.4
4.4 out of 5
4.4 (306)

7 mL / 0.24 fl oz

A deeply hydrating overnight lip mask powered by the OS-01 Peptide™ to restore smoother, fuller, healthier lips.01



  • Stimulates collagen, elastin, and hyaluronic acid production

  • 98% agreed their lips stayed hydrated for 8+ hours; 81% saw fewer wrinkles around the lips

  • Dermatologist tested, fragrance-free, safe for sensitive skin


*Applies clear. Due to natural ingredients, color in compact may vary slightly.

SAVE 15% EVERY ORDER
  • Exclusive early access to new products
  • Earn 2x points on all recurring orders
  • Easily change, skip or cancel anytime

✭ You’re earning 35 points with OneSkin Loyalty Program ✭

For recurring orders, please keep your metal applicator and mirrored compact to use with future refills.

OneSkin

Free shipping on orders over $79.00 USD

OneSkin

Try it risk-free for 30 days!

OneSkin

You’re earning [potential_points] points with OneSkin Loyalty Program

  • Accepted National Eczema Association logo
  • Leaping bunny certified logo

How to apply OS-01 LIP

Using the metal applicator, apply a generous layer onto clean, dry lips as needed.

For a deep treatment, apply before bed and leave on overnight.

HOW OS-01 WORKS

The science to unlock your healthiest skin

Backed by over a decade of longevity research, the OS-01 Peptide™ targets the cells that speed up the visible signs of aging.02

OS-01 is scientifically proven to:

  • Support repair by reducing the buildup of senescent “zombie” cells
  • Improve how skin behaves, stimulating collagen and hyaluronic acid production
  • Build resilience, keeping your skin healthy and youthful as you age

Full ingredient list

Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan. *OS-01 PeptideTM

Your OS-01 LIP questions answered

OS-01 LIP MASK

4.4
Rated 4.4 out of 5 stars
Based on 306 reviews
Total 5 star reviews: 230 Total 4 star reviews: 23 Total 3 star reviews: 23 Total 2 star reviews: 18 Total 1 star reviews: 12
83%would recommend this product
306 reviews
  • NS
    Natalie S.
    Verified Buyer
    Reviewing
    OS-01 LIP MASK
    I recommend this product
    Rated 5 out of 5 stars
    22 seconds ago
    So luxurious

    I love this balm, its so pretty and not too tacky to the touch. I love the applicator and the compact having a miror too

  • AC
    Amanda C.
    Verified Buyer
    Reviewing
    OS-01 LIP MASK
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Unfortunately for your wallet this is fab

    Best lip mask I’ve used bar none. Of everything I tried this I will absolutely keep purchasing.

  • K
    Kelli
    Reviewing
    OS-01 LIP MASK
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    5 Stars

    My lips feel so moisturized every morning. It is definitely part of my nightly routine that I will not stop doing. I place my mouth tape over it every night and it feels great!

  • K
    Kelli
    Reviewing
    OS-01 LIP MASK
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    5 Stars

    My lips feel so moisturized every morning. It is definitely part of my nightly routine that I will not stop doing. I place my mouth tape over it every night and it feels great!

  • KH
    kerry h.
    Verified Buyer
    Reviewing
    OS-01 LIP MASK
    I do not recommend this product
    Rated 1 out of 5 stars
    1 week ago
    Not worth it

    I really wanted to love this but have my lips more dry and cracked than before using

    I will stick with less expensive drugstore options

    OneSkin
    1 week ago

    Hi Kerry!

    Thank you so much for taking the time to share your honest feedback about OS-01 LIP MASK — we genuinely appreciate it, and we're really sorry to hear that it left your lips feeling more dry and cracked than before. That's absolutely not the result we want for our customers, and we completely understand your frustration.

    We want you to know that your experience is concerning to us because OS-01 LIP MASK was specifically formulated to provide deep overnight hydration and repair for lips. The fact that it had the opposite effect suggests something may not have been right with your specific experience, whether it's an individual sensitivity, application method, or potentially even a product quality issue.

    A couple of things that might be helpful to consider: some customers find that if they apply too thick of a layer initially, it can sometimes cause an adjustment period where lips feel different for the first few uses. Also, because OS-01 LIP MASK is designed as an intensive overnight treatment rather than a daily lip balm, the formulation is quite different from typical drugstore lip products — and sometimes that difference doesn't work well for everyone's individual lip chemistry.

    Your feedback about the product making your lips more dry is really valuable to us as we continue refining our lip care line. We'd love to connect with you personally to understand more about your experience and see how we can make this right for you. Please feel free to reach out to support@oneskin.co so we can help!

    Thank you for giving OneSkin a try, Kerry. We truly appreciate your feedback and want to make sure you find a lip care solution that works well for you.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
02 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1