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OS-01 BODY Topical Supplement

Body

OS-01 BODY Topical Supplement

SUBSCRIPTION EXCLUSIVES

  • Exclusive early access to new products
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  • Suited to All skin types, safe for sensitive skin
  • Format Nourishing moisturizer
  • Targets Crepiness, dehydration, skin barrier function

OS-01 BODY is a restorative skin longevity treatment powered by the OS-01 Senescence Blocking Peptide™, designed to strengthen the skin barrier, improve hydration, and promote firm, resilient skin from the neck down.01

OneSkin

BENEFITS

Nourishing body moisturizer and targeted treatment for thin, crepey skin

Smooth texture

Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01

Deep hydration

Replenishes and locks in hydration to keep skin soft, plump, and nourished.01

Barrier support

Fortifies the skin barrier to protect against daily stressors and moisture loss.01

5-STAR REVIEWS

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

CLINICAL DATA

Visible results, scientifically validated

93

of participants reported improved hydration 01

72

of participants reported improved appearance 01

70

of participants reported improved texture 01

41

Improvement in skin barrier function was measured 01

The Science Behind OS-01 BODY

Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.

To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.01


Shown in lab studies on ex vivo human skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.

Getting started with OS-01 BODY

Follow these easy steps for optimal results

  • Apply to arms, legs, chest, back, and stomach
  • Massage until absorbed
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

All Ingredients

Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide

Citations

01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 BODY Topical Supplement

4.7
Rated 4.7 out of 5 stars
Based on 2,731 reviews
Total 5 star reviews: 2.2k Total 4 star reviews: 367 Total 3 star reviews: 124 Total 2 star reviews: 34 Total 1 star reviews: 40
93%would recommend these products
2,731 reviews
  • K
    Kathy
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    20 minutes ago
    5 Stars

    Best body lotion!!

  • KR
    Karen R.
    Verified Buyer
    Reviewing
    OS-01 BODY Topical Supplement
    I recommend this product
    Rated 5 out of 5 stars
    21 hours ago
    Shock & Awe

    I was months trying to pick between the newest skin care offerings.. system overload. I felt One Skin seemed the most legit. I have severely sun-damaged arms even though I'm olive complected. Never did I expect to see improvement after ONE application. By morning, I couldn't wait to rub in more. I am now religious about the application and bought the face treatment as well. (Not to mention the travel kit.) I wish I had taken before and after of my arms, because I could have become a One Skin model. Sincerely. My rough, pink scar blemishes are diminishing. My raised bumps are almost non-existent. My arms are no longer as rough and they feel hydrated. I'm not as nervous about a friend touching my arm. I'm 66 and also have very thin skin. One Skin seems to be both lessening the severity of and aiding the recovery of my bruising and tearing. I am a gardener as well as a water girl, body boarder, ocean lover.

  • LD
    Lisa D.
    Verified Buyer
    Reviewing
    OS-01 BODY Topical Supplement
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Love it so far

    I have ordered the product twice so far and my skin feels amazing. Not sure if the appearance has changed just yet.

  • MB
    Margaret B.
    Verified Buyer
    Reviewing
    OS-01 BODY Topical Supplement
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Love the 0s-01 body lotion

    The body tropical lotion has made my skin look very soft even after 8 hours.

  • L
    Leanne
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    5 Stars

    Feels good, hydrates well, skin looks better