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Up to 25% off on your first 3 deliveries of a new subscription! Ends 1/19. Terms apply.

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OS-01 BODY MOISTURIZER

Topical Supplement

Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 PeptideTM.01



  • Improves skin texture, appearance, and hydration

  • Strengthens the skin barrier by up to +41%

  • Dermatologist tested, fragrance-free, safe for sensitive skin

  • Exclusive early access to new products
  • Earn 2x points on all recurring orders
  • Easily change, skip or cancel anytime

Limited time offer: Stick with it, save more

1st SHIPMENT
15% off
2nd SHIPMENT
20% OFF
3RD SHIPMENT
25% OFF

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Free shipping on orders over $79.00 USD

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BENEFITS

Nourishing body moisturizer and targeted treatment for thin, crepey skin

Smooth texture

Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01

Deep hydration

Replenishes and locks in hydration to keep skin soft, plump, and nourished.01

Barrier support

Fortifies the skin barrier to protect against daily stressors and moisture loss.01

5-STAR REVIEWS

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

CLINICAL DATA

Visible results, scientifically validated

93

of participants reported improved hydration 01

72

of participants reported improved appearance 01

70

of participants reported improved texture 01

41

Improvement in skin barrier function was measured 01

ONESKIN LONGEVITY SCIENCETM

The Science Behind OS-01 BODY

Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.

To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.01


Shown in lab studies on ex vivo human skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.

Getting started with OS-01 BODY

Follow these easy steps for optimal results

  • Apply to arms, legs, chest, back, and stomach
  • Massage until absorbed
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

All Ingredients

Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide

Citations

01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 BODY MOISTURIZER

4.7
Rated 4.7 out of 5 stars
Based on 3,118 reviews
Total 5 star reviews: 2.5k Total 4 star reviews: 398 Total 3 star reviews: 154 Total 2 star reviews: 41 Total 1 star reviews: 42
92%would recommend these products
3,118 reviews
  • LG
    Lynn G.
    Verified Reviewer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    OBSESSED!

    Just cracked open my scone shipment and I NEVER EVER wan to be without it. I have already noticed a difference on my arms. I will be a customer for life!

  • SY
    Shelly Y.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    2 hours ago
    Supple & Soft

    This lotion has really made a difference in my skin, it is definitely softer and more supple than before and at 60 when your husband compliments how soft your skin is, I think that’s a win. It’s an incredible product.

  • CM
    Cristina M. A.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    4 hours ago
    Softer bouncier skin

    I started using this to improve the appearance of loose skin on my stomach. I'm in good shape but after two kids there is def undulations on my stomach from the stretched skin. I have been using for 7 months and I do see a difference in my skin. It does look more hydrated and plump everywhere I use this. My stomach does look smoother and just like nicer skin. It's hard to explain! My arms and elbows are also the nicest feeling skin now.

  • YT
    Yvonne T. M.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    7 hours ago
    Effective body lotion!

    I am on my 2nd bottle of 0S-01 body lotion. I already see an improvement on my arms and legs. I don’t see as much crepiness. I am beginning to use this on my chest and I am hoping for the same results:).

  • S
    Samuel
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    5 Stars

    Great product