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OS-01 FACE Topical Supplement Refill

OS-01 FACE Topical Supplement Refill

$117.00
Unit price
per 

Smooth and firm skin with our daily moisturizer for the face and neck, powered by the OS-01 Peptide™.01



  • Boosts hydration, elasticity, and barrier function

  • 96% showed an improvement in firmness and radiance

  • Dermatologist tested, fragrance-free, safe for sensitive skin


Reusable plastic shell not included.

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  • Leaping bunny certified logo
  • Accepted National Eczema Association logo
  • Certified Plastic Neutral logo on a white background
  • Clinically Tested to Support the Skin Microbiome

OneSkin

Benefits

Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment

Hydration

Boosts barrier function, allowing your skin to retain moisture and stay hydrated.02

Firmness

Switches off the cells that degrade collagen, helping skin stay firm.01,03

Radiance

Enhances skin tone and texture, helping skin look and feel smooth and radiant.02

5-STAR REVIEWS

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

CLINICAL DATA

Visible results, scientifically validated

100
of participants had improved smoothness 02

96
of participants had improved firmness, radiance, and tone 02

90
of participants had improved elasticity 02

86
of participants had improved appearance of fine lines and wrinkles 02

Getting started with OS-01 FACE

Follow these easy steps for optimal results

  • Dispense 1-2 pumps onto fingers
  • Gently massage into skin on the face and neck
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

OS-01 FACE Topical Supplement Refill

4.7
Rated 4.7 out of 5 stars
Based on 6,325 reviews
Total 5 star reviews: 5.1k Total 4 star reviews: 803 Total 3 star reviews: 256 Total 2 star reviews: 74 Total 1 star reviews: 62
94%would recommend these products
6,325 reviews
  • CM
    Christine M.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Only perfection

    I love this system! Saves on plastic and so easy to manipulate. Well done One Skin.

  • CS
    Carmen S.
    Verified Buyer
    Reviewing
    OS-01 FACE Topical Supplement Refill
    I recommend this product
    Rated 5 out of 5 stars
    2 hours ago
    Love the product!

    Love the product!

  • M
    Marie
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 4 out of 5 stars
    5 hours ago
    4 Stars

    So far ok

  • KR
    Karen R.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Like it!

    i like a moisturizer that doesn’t feel like your washing it off the next morning because it didn’t soak in. This one feels like it sinks into my skin.

  • NR
    Nathalie R.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    Very good, aesthi says skin is much less dehydrated

    I have been using OS-01 for months now. I cannot tell the impact other than that my skin is usually dehydrated as I do not drink enough water and my skin is more fragile with age. But my aesthi said my skin was much less dehydrated than in the past, so I think it is helping, though I use another serum underneath (a DNA repair serum) and typically a moisturizer before sunscreen during the day or heavier cream at night. But prior to use, I was consistently told my skin was dehydrated. So there is progress. Hopefully OS-01 is doing what it is supposed to be doing.

    OneSkin
    Yesterday

    Hi Nathalie!

    Thank you so much for your wonderful 4-star feedback about OS-01 FACE Refill Pouch! We're absolutely thrilled to hear that your aesthetician has noticed such a significant improvement in your skin's hydration levels after months of consistent use - that professional observation about your skin being much less dehydrated is exactly what gets us so excited about our science-backed OS-01 Peptide working at the cellular level!

    We love that you're experiencing those meaningful changes that are being recognized by a skincare professional! Your aesthetician's observation about the dramatic difference in your hydration levels really shows how our carefully crafted formula is working to strengthen your skin barrier and improve moisture retention over time. The fact that this improvement is noticeable to someone who regularly evaluates skin condition is such a testament to the real progress you're making with consistent use.

    Your honest perspective about not being able to see the changes yourself while getting that professional confirmation really shows how skincare improvements often happen gradually and can be more apparent to trained eyes! We completely understand that when you're looking at your skin every day, those positive changes can be subtle and build over time. Having that external validation from your aesthetician about the reduced dehydration is such valuable feedback about how OS-01 FACE is delivering results.

    We're also so glad you've found a routine that works well for you by incorporating OS-01 FACE with your other skincare products! Your approach of layering it with your DNA repair serum and following with appropriate moisturizers shows such thoughtful consideration for creating a comprehensive skincare routine that addresses multiple concerns while allowing each product to do its best work.

    Stories like yours about getting that professional confirmation of improved hydration levels are exactly why we're so passionate about what we do! Your commitment to consistent use over months and the patience to let the formula work really demonstrates the confidence you're building in the OS-01 experience.

    Thank you for taking the time to share such detailed and encouraging feedback about your experience - your 4-star review truly means the world to all of us at OneSkin!