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RICH + EYE DUO

4.7
4.7 out of 5
4.7 out of 5
(2,352)

Deep hydration clinically proven to smooth lines + visibly firm.

  • Age-Reversal Peptide
  • Fine lines
  • Wrinkles
  • Firmness
RICH + EYE DUO
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RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
Save 10%
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO
RICH + EYE DUO

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  • Certified cruelty-freeby The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-freeby The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-freeby The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

Details
  • Smooth, deeply hydrate, and visibly firm skin with a replenishing duo for the face and eye area powered by our proprietary OS-01 Senescence-Blocking Peptide™
  • OS-01 EYE CREAM Improves elasticity and firmness while smoothing the appearance of fine lines and wrinkles1,2 
  • OS-01 FACE RICH CREAM delivers lasting hydration while supporting skin's visible firmness, resilience, and density3
  • Rich, hydrating textures melt into skin with no residue
Clinical proof

OS-01 EYE CREAM 

  • +26% increase in elasticity after 3 months1
  • +27% increase in visible firmness after 12 months2
  • -18% reduction in the appearance of fine lines and wrinkles after 12 months2

OS-01 FACE RICH CREAM

  • 100% saw improved hydration after 6 weeks3
  • 93% agreed their skin retains hydration better over time3
  • 97% saw a reduced appearance of fine lines and wrinkles after 6 weeks3
  • 93% saw improved visible firmness and elasticity after 6 weeks3
  • +38% increase in skin’s hydration after 12 weeks3

The Clinical Studies

OS-01 EYE CREAM: 3-Month Efficacy Study1 

A clinical study conducted by a third-party research organization evaluated the effects of OS-01 EYE CREAM over 3 months in 22 participants aged 47–65. Participants applied OS-01 EYE CREAM to their periorbital skin 2x daily. Assessments included bioinstrumental measurements of skin hydration, barrier function, firmness, and elasticity, as well as expert photographs grading fine lines, wrinkles, under-eye puffiness, and dark circles. The study has been published in the International Journal of Cosmetic Science.

Measured results:

  • +20 increase in hydration after 1 month; +32% increase in hydration after 3 months (Corenometer)
  • +14% increase in elasticity after 1 month; +26% increase in elasticity after 3 months (Cutometer)
  • +10% increase in firmness after 3 months (Cutometer)
  • +10% increase in barrier strength after 1 month; +17% increase in barrier strength after 3 months (Vapometer)

Consumer perception results:

  • 95% observed improved overall appearance after 3 months
  • 91% observed visibly more even tone and smoother texture after 3 months
  • 86% observed more radiant skin after 3 months
  • 82% observed visible improvements in firmness and elasticity after 3 months
  • 77% observed reduced visible eye puffiness after 3 months

OS-01 EYE CREAM: 12-Month Efficacy Study2

A clinical study conducted by a third-party research organization evaluated the effects of OS-01 EYE CREAM over 12 months in 23 participants aged 47–60. Participants applied OS-01 EYE CREAM to their periorbital skin 2x daily and results were assessed by expert clinical grading.

Expert Grading Results:

  • +19% increase in visible firmness after 6 months; +27% increase in visible firmness after 12 months (expert grading)
  • +23% increase in visible elasticity after 6 months; +29% increase in elasticity after 12 months (expert grading)
  • 18% reduction in the appearance of fine lines and wrinkles after 12 months (expert grading)

Consumer perception results:

  • 100% observed improved overall appearance after 12 months
  • 100% observed more radiant skin after 12 months
  • 96% observed visibly more even tone and smoother texture after 12 months
  • 95% observed improved firmness and elasticity after 12 months
  • 86% observed reduced appearance of eye bags after 12 months
  • 86% observed reduced appearance of visible dark spots after 12 months

OS-01 FACE RICH CREAM: 12-Week Efficacy Study3

A 12-week, third-party, double-blind clinical study evaluated the effects of OS-01 FACE RICH CREAM in 29 female participants ages 43-65 with mild to moderate facial skin sagging, firming, contouring, nasolabial folds, and expression lines. Participants applied OS-01 FACE RICH CREAM 2x daily to their face and neck. Barrier function and hydration were measured with instrumental devices (Corneometer, TEWL measurement), while radiance, texture,and hydration were evaluated visually and tactilely by expert clinical graders. Participants also provided subjective assessments via a self-reported questionnaire.

The results after 6 weeks:

  • 100% saw improved hydration
  • 93% agreed their skin retains hydration better over time
  • 97% saw a reduced appearance of fine lines and wrinkles
  • 93% saw improved visible firmness and elasticity
  • 97% reported smoother, softer, more radiant skin

The results after 12 weeks:

  • +38% increase in skin’s hydration
  • 97% had more hydrated skin
  • 97% reported improved overall appearance
  • 90% reported more nourished skin with improved skin quality
  • +37% improvement in skin smoothness
  • 83% agree their skin looks, feels, and acts more youthful
  • 81% saw reduced visible redness and irritation
  • +13% increase in barrier strength

Safety studies

OS-01 FACE RICH CREAM and OS-01 EYE CREAM are non-comedogenic, dermatologist tested, suitable for sensitive skin, fragrance-free, and formulated without parabens, sulfates, phthalates, or other common irritants. Based on their formulas and clinical testing, they have been awarded the National Eczema Association Seal of Acceptance™.

Our commitment to the scientific process

OneSkin products are validated with a rigorous process from the lab to the clinic: Lab testing on human skin to evaluate the effect on the cellular level, consumer testing with real users to ensure optimal texture and feel, and third-party clinical studies to evaluate the effect on the human level over time.
Ingredients

Formulated without
Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.

OS-01 RICH CREAM

Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii (Shea) Nut Extract, Lauryl Olivate, Cetearyl Olivate, Euterpe Oleracea Fruit Oil, Squalane, C10-18 Triglycerides, Glyceryl Stearate SE, Linoleic/Oleic/Palmitic Triglyceride, Saccharide Isomerate, Sorbitan Olivate, Coconut Alkanes, 1,2-Hexanediol, Panthenol, Butyrospermum Parkii (Shea) Butter, Sodium PCA, Collagen Amino Acids, Ectoin, Citrullus Lanatus (Watermelon) Fruit Extract, Ceramide NP, Haematococcus Pluvialis Extract, Lens Esculenta (Lentil) Fruit Extract, Betaine, Coco-Caprylate/Caprate, Pyrus Malus (Apple) Fruit Extract, Moringa Oleifera Seed Oil, Decapeptide-52,* Hexapeptide-9, Tamarindus Indica Seed Polysaccharide, Limnanthes Alba (Meadowfoam) Seed Oil, Macadamia Integrifolia Seed Oil, Phytosphingosine, Sodium Lactate, Tremella Fuciformis Sporocarp Extract, Citric Acid, Sodium Citrate, Caprylyl Glycol, Phaeodactylum Tricornutum Extract, Cholesterol, Lecithin, Caprylhydroxamic Acid, Tocopherol, Propanediol, Sorbitan Oleate, Sorbitan Palmitate, Cetyl Palmitate, Dilinoleic Acid/Propanediol Copolymer, Sodium Phytate, Xanthan Gum, Cetearyl Alcohol, Hydroxyacetophenone, Sodium Benzoate.
*OS-01 Peptide™

OS-01 EYE CREAM:

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. 
*OS-01 Peptide™

This set includes

Clear bottle with black pump and 'One Skin' label on a light beige background

STEP 1

OS-01 EYE CREAM

Nourishing hydration that improves elasticity + firmness.

Size

20 mL / .67 fl oz

How to use

Gently tap 1⁄2-1 pump around each eye.

OS-01 FACE RICH CREAM

STEP 2

OS-01 FACE RICH CREAM

Clinically proven to deeply hydrate and visibly firm over time.

Size

50 mL / 1.7 fl oz

How to use

Smooth a generous layer onto clean, dry skin on the face, neck, and chest. Use 2x daily, morning and evening. Results require consistency.

OS-01 Peptide logo featuring a solid orange square on the left, followed by the text 'OS-01' in black and 'PEPTIDE' in bold black letters, with a small trademark symbol.

Engineered to reverse skin’s visible biological age.4

Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid and barrier strength. The result: skin that looks, feels, and acts younger over time.

Explore the science →

Clinically validated results that build over time

93%

saw improved visible firmness and elasticity after 12 weeks1

+37%

improvement in skin smoothness after 12 weeks1

Clinically validated results that build over time

Week 1

Deep, replenishing hydration

  • The OS-01 Peptide™ gets to work immediately
  • Bioactive humectants draw hydration deep into skin
  • Skin-identical lipids seal the moisture barrier
Week 6

Firmer, more resilient skin

  • 100% saw improved hydration1
  • 93% agreed their skin retains hydration better over time1
  • 97% saw a reduced appearance of fine lines and wrinkles1
  • 93% saw improved visible firmness1
Week 12

Smoother, more youthful skin

  • +38% increase in skin’s hydration1
  • +37% smoother skin1
  • 97% reported improved overall appearance1
  • 90% reported more nourished skin with improved skin quality1
  • 83% agree their skin looks, feels, and acts more youthful1

Key ingredients

OS-01 Peptide™

Proven to reverse skin's visible biological age by reversing the visible effects of senescent (dysfunctional, aging) cells.

Palmless™ torula oil

An antioxidant-packed emollient that boosts barrier strength + reduces the appearance of fine lines and wrinkles.

Tremella fuciformis mushroom extract

A naturally derived extract that helps skin hold more hydration while supporting antioxidant defense.

Vegan collagen amino acids

Spermidine-rich upcycled microalgae shown to visibly boost collagen synthesis and volumize skin’s matrix.

All ingredients

Formulated without
Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.

OS-01 RICH CREAM

Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii (Shea) Nut Extract, Lauryl Olivate, Cetearyl Olivate, Euterpe Oleracea Fruit Oil, Squalane, C10-18 Triglycerides, Glyceryl Stearate SE, Linoleic/Oleic/Palmitic Triglyceride, Saccharide Isomerate, Sorbitan Olivate, Coconut Alkanes, 1,2-Hexanediol, Panthenol, Butyrospermum Parkii (Shea) Butter, Sodium PCA, Collagen Amino Acids, Ectoin, Citrullus Lanatus (Watermelon) Fruit Extract, Ceramide NP, Haematococcus Pluvialis Extract, Lens Esculenta (Lentil) Fruit Extract, Betaine, Coco-Caprylate/Caprate, Pyrus Malus (Apple) Fruit Extract, Moringa Oleifera Seed Oil, Decapeptide-52,* Hexapeptide-9, Tamarindus Indica Seed Polysaccharide, Limnanthes Alba (Meadowfoam) Seed Oil, Macadamia Integrifolia Seed Oil, Phytosphingosine, Sodium Lactate, Tremella Fuciformis Sporocarp Extract, Citric Acid, Sodium Citrate, Caprylyl Glycol, Phaeodactylum Tricornutum Extract, Cholesterol, Lecithin, Caprylhydroxamic Acid, Tocopherol, Propanediol, Sorbitan Oleate, Sorbitan Palmitate, Cetyl Palmitate, Dilinoleic Acid/Propanediol Copolymer, Sodium Phytate, Xanthan Gum, Cetearyl Alcohol, Hydroxyacetophenone, Sodium Benzoate.
*OS-01 Peptide™

OS-01 EYE CREAM:

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. 
*OS-01 Peptide™

OneSkin Longevity Protocol

RICH + EYE DUO

Write a Review (Opens in a new tab)
2,352 reviews
  • SS
    Stephanie S.
    Verified Buyer
    Reviewing
    OS-01 FACE RICH CREAM
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Just what I wanted

    I have been using a One Skin skin care regimen for years now with excellent results. I enjoy 4 seasons a year where I live and I noticed in the driest winter months I needed a little extra moisture to keep all my hydration from evaporating so I was using face oil on top to keep my skin from drying out. I kept thinking it would be nice to have a more emollient version of OS and here it is! Coupled with the dispenser which prevents contamination, I could not be more happy with this simple swap in my routine when winter dry weather comes calling - thanks a ton One Skin.

    Was this helpful?
  • CM
    Catherine M.
    Verified Buyer
    Reviewing
    OS-01 FACE RICH CREAM
    I recommend this product
    Rated 5 out of 5 stars
    1 hour ago
    Firmer cheeks

    While I loved my Grannie's soft, loose, lily of the valley scented cheeks when I was a young child, I'd much rather my own cheeks not be lax. In well under a month of twice daily use, my own cheeks are firm and bouncy.

    Was this helpful?
  • MW
    Maria w.
    Verified Buyer
    Reviewing
    RICH + EYE DUO
    I recommend this product
    Rated 5 out of 5 stars
    11 hours ago
    Rich - eye duo

    Loving it so far

    Was this helpful?
  • R
    rosie
    Reviewing
    OS-01 FACE RICH CREAM
    I recommend this product
    Rated 5 out of 5 stars
    12 hours ago
    5 Stars

    Love the cream beautiful

    Do Not like the packaging because having any type of packaging that is made to look bigger & is actually small amount of product inside is misleading & annoying.

    Was this helpful?
  • SS
    shelly s.
    Verified Buyer
    Reviewing
    OS-01 FACE RICH CREAM
    Rated 3 out of 5 stars
    14 hours ago
    Just ok. Not amazing

    This cream is just OK. For what you get in the terrible packaging. I think it’s too expensive.

    Was this helpful?
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Citations

  1. Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025.) 
  2. Based on a third-party 12-month clinical study with 23 participants aged 47–60. 
  3. Based on a double-blind, third-party 12-week clinical study with 29 participants aged 43-65.
  4. Visible biological age defined as signs of aging such as smoothness and barrier strength. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)