How is OS-01 EYE different from OS-01 FACE?

4 min read

April 25,2023
ONESKIN PRODUCTS

How is OS-01 EYE different from OS-01 FACE?

4 min read

April 25,2023
ONESKIN PRODUCTS
Many of us have spent decades wondering if we really need any eye cream. How different can they actually be from the products we’re already using on the rest of the face? When we set out to formulate OS-01 EYE, it was important to us to create a product that was functionally different from OS-01 FACE – and specifically designed to treat the skin around the eyes. One thing both formulas have in common? OS-01, our breakthrough innovation and the first peptide proven to reduce skin’s biological age, support cellular repair, increase epidermal thickness, improve barrier function, and increase biomarkers associated with collagen production.[1, 2, 3] To understand how and why the two formulas are different, let’s take a closer look at the science.
Many of us have spent decades wondering if we really need any eye cream. How different can they actually be from the products we’re already using on the rest of the face? When we set out to formulate OS-01 EYE, it was important to us to create a product that was functionally different from OS-01 FACE – and specifically designed to treat the skin around the eyes. One thing both formulas have in common? OS-01, our breakthrough innovation and the first peptide proven to reduce skin’s biological age, support cellular repair, increase epidermal thickness, improve barrier function, and increase biomarkers associated with collagen production.[1, 2, 3] To understand how and why the two formulas are different, let’s take a closer look at the science.
01

How Is Eye-Area Skin Actually Different?

The skin around the eyes is very thin, with a stratum corneum that’s on average about 3 layers thick compared to 15+ layers on other areas.[4] This incredible skin thinness means your under eyes experience more exaggerated signs of collagen and elastin loss than the rest of your face–namely fine lines, sagging, and crepiness. [5,6]Eye-area skin has also been shown to actually age faster than the rest of our faces. In a study, scientists measured the biological age of eye skin and compared it to skin just inches away on the temple. What they found was that the skin under the eyes was biologically 22.25 years older. [6]This difference in biological age may be largely due to increased rates of cellular senescence around the eyes. In a study, scientists analyzed the expression of a key senescence marker, CDK2NA, in periocular skin. What they found was that periocular skin expressed significantly higher levels of cellular senescence than other areas of the face. [6]
01

How Is Eye-Area Skin Actually Different?

The skin around the eyes is very thin, with a stratum corneum that’s on average about 3 layers thick compared to 15+ layers on other areas.[4] This incredible skin thinness means your under eyes experience more exaggerated signs of collagen and elastin loss than the rest of your face–namely fine lines, sagging, and crepiness. [5,6]Eye-area skin has also been shown to actually age faster than the rest of our faces. In a study, scientists measured the biological age of eye skin and compared it to skin just inches away on the temple. What they found was that the skin under the eyes was biologically 22.25 years older. [6]This difference in biological age may be largely due to increased rates of cellular senescence around the eyes. In a study, scientists analyzed the expression of a key senescence marker, CDK2NA, in periocular skin. What they found was that periocular skin expressed significantly higher levels of cellular senescence than other areas of the face. [6]
02

How is OS-01 EYE Different from OS-01 FACE?

In order to address the significantly higher levels of cellular senescence around the eyes, we formulated OS-01 EYE with the highest concentration of our OS-01 peptide. In lab studies on human skin samples, the OS-01 peptide was shown to reduce the overall number of senescent cells.[1, 3] By powering OS-01 EYE with more OS-01 peptide, it is better equipped to help counteract the accelerated aging process that occurs around the eyes.In addition to different concentrations of the OS-01 peptide, OS-01 EYE and OS-01 FACE contain different supporting ingredients, carefully blended to be gentle on sensitive and problematic skin. As always, we chose scientifically validated ingredients that magnify the benefits of the OS-01 peptide, offering additional damage repair benefits, barrier support, and enhanced hydration.
02

How is OS-01 EYE Different from OS-01 FACE?

In order to address the significantly higher levels of cellular senescence around the eyes, we formulated OS-01 EYE with the highest concentration of our OS-01 peptide. In lab studies on human skin samples, the OS-01 peptide was shown to reduce the overall number of senescent cells.[1, 3] By powering OS-01 EYE with more OS-01 peptide, it is better equipped to help counteract the accelerated aging process that occurs around the eyes.In addition to different concentrations of the OS-01 peptide, OS-01 EYE and OS-01 FACE contain different supporting ingredients, carefully blended to be gentle on sensitive and problematic skin. As always, we chose scientifically validated ingredients that magnify the benefits of the OS-01 peptide, offering additional damage repair benefits, barrier support, and enhanced hydration.
03

What are the Supporting Ingredients in OS-01 EYE?

  • Moringa Oleifera Seed Extract: Extracted from the seeds of the moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging.
  • Vitamin E and Ubiquinone: Delivers high concentrations of antioxidants via coenzyme Q10 and vitamin E to shield against extrinsic aging factors.
  • Fucus Vesiculosus Algae Extract: This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.
  • Biomimetic Vegan Collagen: This biodesigned vegan collagen peptide is the first human mimetic and boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to penetrate the skin barrier.
  • Cystoseira Humilis Seaweed Extract: This antioxidant-packed seaweed extract is rich in bioactive moisturizers that improve firmness, hydration and skin protection.
  • Coffee Extract: Extracted from organic green coffee beans, this extract stimulates mitochondrial function to support skin cell regeneration.
  • Acetyl Hexapeptide-8 (Progeline): This peptide reduces the look of wrinkles by limiting the overproduction of neurotransmitters that control facial muscle contractions.
03

What are the Supporting Ingredients in OS-01 EYE?

  • Moringa Oleifera Seed Extract: Extracted from the seeds of the moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging.
  • Vitamin E and Ubiquinone: Delivers high concentrations of antioxidants via coenzyme Q10 and vitamin E to shield against extrinsic aging factors.
  • Fucus Vesiculosus Algae Extract: This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.
  • Biomimetic Vegan Collagen: This biodesigned vegan collagen peptide is the first human mimetic and boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to penetrate the skin barrier.
  • Cystoseira Humilis Seaweed Extract: This antioxidant-packed seaweed extract is rich in bioactive moisturizers that improve firmness, hydration and skin protection.
  • Coffee Extract: Extracted from organic green coffee beans, this extract stimulates mitochondrial function to support skin cell regeneration.
  • Acetyl Hexapeptide-8 (Progeline): This peptide reduces the look of wrinkles by limiting the overproduction of neurotransmitters that control facial muscle contractions.
04

What are the Supporting Ingredients in OS-01 FACE?

  • Pracaxi Oil: Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.
  • Andiroba Oil: A seed oil that promotes healthy collagen and minimizes the effects of inflammation.
  • Niacinamide: A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.
  • Oleic Pau Mulato extract: An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.
  • Allantoin: A skin-conditioning molecule that moisturizes and soothes irritated skin.
  • Hyaluronic acid: A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
04

What are the Supporting Ingredients in OS-01 FACE?

  • Pracaxi Oil: Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.
  • Andiroba Oil: A seed oil that promotes healthy collagen and minimizes the effects of inflammation.
  • Niacinamide: A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.
  • Oleic Pau Mulato extract: An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.
  • Allantoin: A skin-conditioning molecule that moisturizes and soothes irritated skin.
  • Hyaluronic acid: A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
05

How Does OS-01 EYE Specifically Benefit Skin Around the Eyes?

In a 12-week clincial study, OS-01 EYE significantly improved hydration, elasticity, and firmness, as measured by instrumental analysis to remain completely unbiased. In addition, OS-01 EYE improved skin barrier function by an average of +17%, also measured by instrumental analysis. 96% of users noticed an improvement in tone, texture, and overall appearance, and 92% noticed an improvement in radiance.
05

How Does OS-01 EYE Specifically Benefit Skin Around the Eyes?

In a 12-week clincial study, OS-01 EYE significantly improved hydration, elasticity, and firmness, as measured by instrumental analysis to remain completely unbiased. In addition, OS-01 EYE improved skin barrier function by an average of +17%, also measured by instrumental analysis. 96% of users noticed an improvement in tone, texture, and overall appearance, and 92% noticed an improvement in radiance.
06

How Does OS-01 FACE Specifically Benefit Skin On The Face?

In a 12-week clinical study, OS-01 FACE was shown to have visible benefits on the face. At least 90% of users saw an improvement in skin elasticity, evenness, radiance, pores and firmness. 87% of users saw a reduction in fine lines and wrinkles while 100% of users saw an improvement in skin smoothness and overall appearance. Plus, OS-01 FACE has been shown to improve skin barrier function by an average of +15%, helping to enhance the skin's ability to protect against environmental aggressors.
06

How Does OS-01 FACE Specifically Benefit Skin On The Face?

In a 12-week clinical study, OS-01 FACE was shown to have visible benefits on the face. At least 90% of users saw an improvement in skin elasticity, evenness, radiance, pores and firmness. 87% of users saw a reduction in fine lines and wrinkles while 100% of users saw an improvement in skin smoothness and overall appearance. Plus, OS-01 FACE has been shown to improve skin barrier function by an average of +15%, helping to enhance the skin's ability to protect against environmental aggressors.
07

How Should You Use OS-01 EYE With OS-01 FACE?

To get maximum benefits from both formulas, apply OS-01 EYE 2x daily to the skin around the eyes just after cleansing with PREP. Follow with OS-01 FACE on the rest of your face.
07

How Should You Use OS-01 EYE With OS-01 FACE?

To get maximum benefits from both formulas, apply OS-01 EYE 2x daily to the skin around the eyes just after cleansing with PREP. Follow with OS-01 FACE on the rest of your face.
Key Takeaways:
  • OS-01 EYE was formulated specifically for the thinner skin around the eyes, which shows higher rates of cellular senescence and accelerated aging.
  • To address this difference in eye skin, we infused OS-01 EYE with a higher concentration of our OS-01 peptide than what we use in OS-01 FACE.
  • In addition to different concentrations of the OS-01 peptide, OS-01 EYE and OS-01 FACE contain different supporting ingredients selected for their areas of focus.
  • To use OS-01 EYE and OS-01 FACE together, apply OS-01 EYE twice daily before applying OS-01 FACE.
Key Takeaways:
  • OS-01 EYE was formulated specifically for the thinner skin around the eyes, which shows higher rates of cellular senescence and accelerated aging.
  • To address this difference in eye skin, we infused OS-01 EYE with a higher concentration of our OS-01 peptide than what we use in OS-01 FACE.
  • In addition to different concentrations of the OS-01 peptide, OS-01 EYE and OS-01 FACE contain different supporting ingredients selected for their areas of focus.
  • To use OS-01 EYE and OS-01 FACE together, apply OS-01 EYE twice daily before applying OS-01 FACE.
References
References

Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin

Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.

Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin

Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.

Discover More

What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Tips and Tricks for a Youthful Neck
Woman applying sunscreen
Addressing the Need for Indoor Sun Protection
Sunburned skin
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
Pollution
Can Air Quality Affect Skin? Exploring the Impact ...
Close up of eye
Understanding the Relationship Between Sleep and U...
Woman not sleeping in bed
Exploring the Effects of Quality Sleep on Your Ski...
Gut microbiom illustration
How to Improve Gut Microbiome
Woman holding bowl of food
Exploring Caloric Restriction and Its Effects on A...
woman stretching in bed
What’s the Connection Between Quality Sleep and Lo...
Healthy foods
Unlocking the Skin Benefits of Intermittent Fastin...
woman exercising
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
The Microbiome Diet and Its Effects on Skin
cold water
Cold Exposure: Hype or Longevity Boosting?
healthy foods
Eat Better, Live Longer: Top Foods for Longevity
How Environmental Stressors Affect Skin
How to Protect Your Skin from Everyday Environment...
OS-01 BODY
Pressing the Pause Button on Aging Skin: OS-01 BOD...
lip treatment
Lip Balm Ingredients: What to Look for and What to...
earth
Exploring Blue Zones: How Can We Optimize Our Heal...
Sunburn
Sun Exposure and Your Skin: 6 Things You Need to K...
Lips
Nurturing Your Lips: How to Keep Them Moisturized ...
Lips
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care
How to Travel with Skin Care Products
SHIELD on arm
The Importance of Sunscreen: Why Should You Wear I...
Lip sunscreen
Lip Sunscreen: Do Lips Need SPF Protection?
heart hands
The Science of Gratitude
prep on shoulder
Removing Sunscreen: Tips for Clean and Healthy Ski...
freckled skin
Skin Explained: Is Skin An Organ?
UV Light and Skin
UV Light and Skin: Effects and Protection Strategi...
What is Epidermis
Understanding The Epidermis: Functions, Compositio...
Diving into dermis
Diving into Dermis: Functions and Significance
Why Do We Get Wrinkles
Unlocking the Science of Wrinkles: Causes, Formati...
Back skin
Why Skin Barrier is Important
bentonite clay
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
hypodermis function
Hypodermis: Exploring Its Vital Functions
oil-dropper-background-pink-dripping-cosmetic-product
The EU is Limiting Retinol in Skincare: Here’s Eve...
face+shield
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage
The Lip Lineage: Exploring the Why Behind Wrinkled...
A Journey Through the Skin: How UV Radiation Cause...
How to Address Stomach Wrinkles
How to Address Stomach Wrinkles For Smoother Skin
How to Get Rid of Wrinkly Skin on Arms
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
How Do Our Products Work Together?
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
What is Tinted Sunscreen?
two types of face wrinkles
2 Types of Wrinkles and Tips for Treating Them
 Zinc Oxide
The Top 5 Benefits of Zinc Oxide for Skin
Marionette Lines
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger