This is a carousel. Use Next and Previous buttons to navigate

This is a carousel. Use Next and Previous buttons to navigate

Free shipping on orders over $79.00 USD

OS-01 FACE Refill Pouch

OS-01 FACE Refill Pouch

OS-01 FACE Refill Pouch, 50 mL


**Reusable plastic shell not included**


The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.

SAVE 15%
  • Exclusive early access to new products
  • Earn 2x points on all recurring orders
  • Easily change, skip or cancel anytime

✭ You’re earning 99 points with OneSkin Loyalty Program ✭

OneSkin

Try it risk-free! 45 day money back guarantee.

OneSkin

Get free standard shipping on all US orders with code FREESHIP. Terms apply.

OneSkin

You’re earning [potential_points] points with OneSkin Loyalty Program

“By preventing senescent cells from releasing pro-aging factors, we can prevent healthy cells from becoming “zombies”–containing the spread of senescence and slowing down skin aging.” 3Science2

Alessandra Zonari, PhD
OneSkin Co-Founder & CSO 3Science2
OneSkin

OS-01 Peptide 3Science2

Our OS-01 formula targets aging at the cellular level, leaving skin nourished and resilient to daily stress 3Science2

Science Driven Innovation 3Science2

Utilizing advanced research to create effective skincare solutions. 3Science2

Inclusivity and Accessibility

Catering to a diverse range of skin types and needs.

Longevity and Sustainability

Focusing on long-term skin health and eco-friendly practices.

the 30-day one skin challenge

Instantly hydrated,deeply nourished skin 3Science2

93% agree their skin feels protected

87% agree skin looks visibly firmer

80% agree their skin appears to regenerate overnight

OUR APPROACH

Results that go beyond the lab 3Science2

7
Years of Research 3Science2

900
Peptides Screened

0
Patents & Publications

9000
Patents & Publications

OneSkin

Behind One Skin Longevity 3Science2

3Science2 As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning.

  1. Possible Increase of Skin’s Epidermal Thickness
  2. Increase of Key Biomarkers Associated with Cell Proliferation and Collagen Production
  3. May promote cell proliferation and collagen production, which can promote firmer, more renewed skin.
  4. Retinol Increases a Key Marker Associated with Skin Aging. OS-01 FACE Does Not.

How to apply OS-01 FACE and add to your routine 3Science2

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aenean dapibus ac erat in consequat.

  • Dispense 1-2 pumps of OS-01 FACE onto fingers
  • Gently massage into skin on the face, neck, and hands
  • Use 2 times daily

3Science2

How it works 3Science2

Powered by the OS-01 Senescence Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03 3Science2

Frequently asked questions 3Science2

OS-01 FACE Refill Pouch

4.7
Rated 4.7 out of 5 stars
Based on 6,222 reviews
Total 5 star reviews: 5k Total 4 star reviews: 789 Total 3 star reviews: 253 Total 2 star reviews: 72 Total 1 star reviews: 62
94%would recommend these products
6,222 reviews
  • CB
    Cristina B.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    5 hours ago
    Amazing

    A wonderful product, reduces fine lines.

  • M
    Mary
    Verified Buyer
    Reviewing
    OS-01 FACE MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Great moisturizer, subtle results

    I've been using this product 1-2x/day for about a year now (I think), and I really like it. It sinks in easily, and my skin feels nicely moisturized after, and really soft. It is a light lotion, so when the weather is cold and dry, I sometimes will wear a heavier moisturizer over the top, but otherwise I don't need more.

    As for results, I have had some visible changes, but they are subtle, and to be honest, I didn't really notice until I compared my skin now to pictures from a year ago. There is definitely softening of lines around the mouth and forehead. Nothing earth-shattering, but honestly, I don't expect earth-shattering results from skincare. I did get a comment from a dermatologist that my skin is thicker than average for my age--whether that's this lotion, genes, or both I have no idea, but I was happy to hear it. :)

  • TD
    Toni D.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    My one and only

    I love one skin face moisturizer. I can't seem to live without it. It is my go-to day and night. How long with a few other regimes? I also use the eye cream which I love and the lip balm. I would recommend them to anybody that wanted smoother healthier skin

  • R
    Ryan
    Verified Reviewer
    Reviewing
    OS-01 FACE MOISTURIZER
    I do not recommend this product
    Rated 1 out of 5 stars
    4 days ago
    Nope

    I have used many medical grade skin care products, and this moisturizer is sticky and even makeup primer and/or tinted moisturizer will go on smoothly over it. I had such high hopes!

    OneSkin
    4 days ago

    Hi Ryan! Thank you so much for taking the time to share your honest feedback about OS-01 FACE MOISTURIZER. We really appreciate you giving it a try, especially with your experience using medical grade skincare products!

    We're so sorry to hear that the texture didn't work well for you and that it felt sticky under your makeup primer and tinted moisturizer.

    Everyone's skin is so unique, and what works beautifully for some doesn't always work for others - even with the most carefully formulated products. Your feedback about the texture and how it layers with other products is really valuable and helps us understand different experiences people have.

    We'd love to share one little tip that might make all the difference: OS-01 FACE is designed to be applied as the very first step after cleansing, so the OS-01 peptide can absorb deeply into the skin before anything else goes on top. Giving it just a few minutes to fully sink in before layering your primer or tinted moisturizer can really change how everything sits and feels.

    Thank you for sharing your honest experience with your 1-star review - all feedback, including experiences like yours, truly matters to all of us at OneSkin!

  • NH
    Natalie H.
    Verified Buyer
    Reviewing
    OS-01 FACE Topical Supplement Refill
    I recommend this product
    Rated 5 out of 5 stars
    5 days ago
    Great face cream

    I will only buy this cream for the foreseeable future. It feels great going on and is not greasy (big criteria for me).

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
02 Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05 https://academic.oup.com/bbb/article/72/12/3211/5941013 06 https://pubmed.ncbi.nlm.nih.gov/32522955/ 07 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886

Grid item

Perfect for lookbooks and editorial photography

Grid item

Perfect for lookbooks and editorial photography

Rich text

Use this text area to share information about your brand with your customers. Describe a product, share announcements, or welcome customers to your store.

  • Use this text area to share information about your brand with your customers. Describe a product, share announcements, or welcome customers to your store.
  • Use this text area to share information about your brand with your customers. Describe a product, share announcements, or welcome customers to your store.

App section