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Invasive Vs. Non-Invasive Skincare: How to Choose the Right Path for You
6 min read
DEC 5, 2022 - Annie moberg
SKIN CARE
Our store
Invasive Vs. Non-Invasive Skincare: How to Choose the Right Path for You
6 min read
DEC 5, 2022 - Annie moberg
SKIN CARE
As we age, many of us wish we could turn back the hands of time, or at least look like we have. While aging is something worth embracing and celebrating, our feelings about it aren’t always that simple. We want to look our best and feel our best–no matter our age–which means that many of us may have at least considered procedures and treatments that combat visible signs of aging. If you yourself have reached this point, you know that there are two primary types of treatments available: invasive and non-invasive. Not sure how far you’re willing to go? Let’s look at the risks and benefits of many common skin care treatments to get a better understanding of what’s available.
As we age, many of us wish we could turn back the hands of time, or at least look like we have. While aging is something worth embracing and celebrating, our feelings about it aren’t always that simple. We want to look our best and feel our best–no matter our age–which means that many of us may have at least considered procedures and treatments that combat visible signs of aging. If you yourself have reached this point, you know that there are two primary types of treatments available: invasive and non-invasive. Not sure how far you’re willing to go? Let’s look at the risks and benefits of many common skin care treatments to get a better understanding of what’s available.
01
What is invasive skin care?
The most commonly accepted definition of an invasive procedure is one where a trained professional–usually a plastic surgeon–penetrates the skin with an incision to make structural changes to the skin. Generally, invasive procedures require time for recuperation and are accompanied by the same significant risks as any surgery. Pros of Invasive ProceduresFor people looking for a dramatic change, invasive procedures can seem appealing. Take, for instance, one of the most popular invasive skincare treatments: the facelift. Also referred to as “rhytidectomy” by plastic surgeons, facelifts are an effective way to tighten sagging skin and eliminate wrinkles quickly. This surgical procedure lifts the skin on one or both sides of the neck or face, tightening facial muscles and readjusting how skin falls over the face.[2]Other procedures, like thread lifts, are considered only “minimally” invasive procedures by the American Society of Plastic Surgeons. Sometimes called a “lunchtime lift,” a thread lift places absorbable barbed sutures under the skin to create tautness in the face and neck. Thread lifts are ideal for small, contained areas like the eyebrows, neck, or temples.[3]Cons of Invasive ProceduresGoing “under the knife” can be a monumental commitment with a hefty price tag: the average cost of a facelift, excluding anesthesia and recovery, is about $8,000.[7]While invasive skin procedures offer noticeable results, they can come with lengthy healing time and potentially serious health risks. The recovery period for invasive procedures may take weeks and commonly include pain, swelling, and bruising. Results are usually permanent unless corrected by more surgery. Other possible adverse effects worth considering include::
- Nerve injury resulting in temporary weakness or numbness in the skin. In some cases, nerve changes may be permanent.[4]
- Invasive surgical procedures often require local or general anesthesia, which carries its own risk of adverse reaction.[4]
- Significant hematomas —more commonly known as bruises — can result in prolonged discoloration.[5]
- People who have pre-existing conditions, like diabetes, or who are chronic smokers may experience a longer healing process than usual.[4]
- Scarring can differ from person to person. Individuals who tend to develop keloid scars may require further treatments to manage scarring. Keloid scars are raised and much more noticeable than typical scars, and can result in uncomfortable itching.[5]
- Temporary or permanent hair loss may occur at the sites of the incision. Hair transplantation can regrow hair in areas where hair loss is permanent.[6]
01
What is invasive skin care?
The most commonly accepted definition of an invasive procedure is one where a trained professional–usually a plastic surgeon–penetrates the skin with an incision to make structural changes to the skin. Generally, invasive procedures require time for recuperation and are accompanied by the same significant risks as any surgery. Pros of Invasive ProceduresFor people looking for a dramatic change, invasive procedures can seem appealing. Take, for instance, one of the most popular invasive skincare treatments: the facelift. Also referred to as “rhytidectomy” by plastic surgeons, facelifts are an effective way to tighten sagging skin and eliminate wrinkles quickly. This surgical procedure lifts the skin on one or both sides of the neck or face, tightening facial muscles and readjusting how skin falls over the face.[2]Other procedures, like thread lifts, are considered only “minimally” invasive procedures by the American Society of Plastic Surgeons. Sometimes called a “lunchtime lift,” a thread lift places absorbable barbed sutures under the skin to create tautness in the face and neck. Thread lifts are ideal for small, contained areas like the eyebrows, neck, or temples.[3]Cons of Invasive ProceduresGoing “under the knife” can be a monumental commitment with a hefty price tag: the average cost of a facelift, excluding anesthesia and recovery, is about $8,000.[7]While invasive skin procedures offer noticeable results, they can come with lengthy healing time and potentially serious health risks. The recovery period for invasive procedures may take weeks and commonly include pain, swelling, and bruising. Results are usually permanent unless corrected by more surgery. Other possible adverse effects worth considering include::
- Nerve injury resulting in temporary weakness or numbness in the skin. In some cases, nerve changes may be permanent.[4]
- Invasive surgical procedures often require local or general anesthesia, which carries its own risk of adverse reaction.[4]
- Significant hematomas —more commonly known as bruises — can result in prolonged discoloration.[5]
- People who have pre-existing conditions, like diabetes, or who are chronic smokers may experience a longer healing process than usual.[4]
- Scarring can differ from person to person. Individuals who tend to develop keloid scars may require further treatments to manage scarring. Keloid scars are raised and much more noticeable than typical scars, and can result in uncomfortable itching.[5]
- Temporary or permanent hair loss may occur at the sites of the incision. Hair transplantation can regrow hair in areas where hair loss is permanent.[6]
02
In-Office Non-invasive Skin Tightening Techniques
If you’re considering a non-invasive treatment, you have plenty of options. Here are some of the most popular in-office treatments. Ablative Laser TreatmentsAblative laser treatments, also called laser resurfacing, remove the outer layers of damaged skin to encourage the creation of new skin cells. Ablative lasers use intense light wavelengths to slightly wound the skin. This triggers the skin’s healing response, stimulating new collagen formation to help repair the damage. As the skin heals, damaged skin is sloughed away, revealing smoother and tighter-looking skin beneath it. This can be especially helpful for deep textural imperfections including wrinkles and acne scarring. In fact, JAMA Dermatology recognizes ablative laser treatments as an effective form of scar treatment.[11]Ablative laser treatments require considerable pre-treatment and post-treatment attention. A physician may prescribe an antiviral medication before and after the procedure as a precaution if you are prone to infections. Some treatments may require sedation, depending on the type of ablation and the treated area. After treatment, you can expect pain, swelling and discomfort for up to two weeks. You’ll also need to avoid unprotected sun exposure to prevent serious skin damage. [12]Non-Ablative Laser TreatmentUnlike standard ablative laser treatments, non-ablative laser treatments for skin tightening stimulate collagen production to improve skin texture without wounding the skin. Because this non-invasive skin resurfacing procedure is gentler on the skin, the recovery time is much shorter and less painful. Non-ablative skin tightening skin treatments may not offer the same level of results as ablative laser procedures, but over time they can result in smoother skin and a more even skin tone.Ultrasound for Skin TighteningMost of us are familiar with ultrasound's use in medical diagnostics and obstetrics, but ultrasound energy is also beneficial for keeping the skin firm and smooth. Ultrasound targets the lower layers of skin below the epidermis. During the procedure, ultrasound is transmitted through the skin to heat the skin at depths of up to 5mm. The gentle heat stimulates collagen production, resulting in firmer-looking skin. Targeting specific areas, ultrasound skin tightening rejuvenation treatments can improve elasticity in places where it’s often needed the most — the middle and lower face. When used on sagging skin in these areas, ultrasound treatments can offer a viable alternative to a mini-facelift.[13]In fact, a 2018 study published in the journal Plastic and Reconstructive Surgery evaluated the effectiveness of focused ultrasound on 50 adults with lower and mid-face sagging. After six months, participants were assessed by third-party evaluators and also by a self-assessment questionnaire. The evaluators saw improvements in 93% of the participants. About 85% of participants themselves saw positive changes in their skin, according to the self-assessment questionnaires.[14]The side effects of ultrasound treatments for skin tightening are often temporary. During the procedure, clients may experience some discomfort. Afterwards, redness, numbness, and slight bruising may occur for a short period.[15]Radiofrequency (RF) treatmentsLike ultrasound treatments, radiofrequency (RF) energy can be used to heat the skin in order to boost collagen production. RF treatments concentrate heat onto the upper layers of skin to reduce wrinkling and tighten minor sagging. A 2018 study published in the Annals of Dermatology found that three RF energy treatments performed over six weeks [16] on older adults resulted in significant wrinkle reduction. Another small study focused on the use of RF energy for facial contouring. Of the 11 participants in the study, 73% saw improvements in facial contours when RF was combined with electromagnetic treatments.[17]Radiofrequency treatments are available for use on the face, neck, and body and are performed in-office. Treatments can also be combined with other non-invasive aesthetic procedures, like microneedling and ultrasound to target multiple layers of skin. Because RF energy heats skin layers, side effects include burning and temporary pain.[18]LED Light TherapyThe sun’s ultraviolet rays are dangerous for unprotected skin, but not all light rays are harmful. In fact, light rays of different frequencies can actually have healing properties. LED light therapy harnesses red, blue, and near-infrared light to safely renew and firm damaged skin. LED light therapy not only stimulates collagen but also kills acne-causing bacteria that can trigger breakouts. Interestingly, NASA initially used LED light therapy aboard space shuttle missions to promote wound healing. In fact, a published study indicated that LED light therapy promoted skin healing in 40% of its participants.[20] Soon, researchers noticed that skin that was exposed to the therapy also appeared smoother. [19] Side effects are minimal when LED treatments are conducted in a dermatology office. Chemical PeelsChemical peels, also called chemexfoliation or derma-peeling, utilize a variety of chemical agents to exfoliate skin cells on the mid to outer layers of skin, encouraging new cell development and collagen synthesis. [21] Chemical peels fall into three categories based on strength:[22]
- Superficial peels that use mild acids to penetrate the outermost layers of skin.
- Medium peels use glycolic acid or trichloroacetic to remove the outer layers of skin and those right beneath the top layer.
- Deep peels that reach the middle layer of skin, using phenol or trichloroacetic acid to remove damaged cells.
02
In-Office Non-invasive Skin Tightening Techniques
If you’re considering a non-invasive treatment, you have plenty of options. Here are some of the most popular in-office treatments. Ablative Laser TreatmentsAblative laser treatments, also called laser resurfacing, remove the outer layers of damaged skin to encourage the creation of new skin cells. Ablative lasers use intense light wavelengths to slightly wound the skin. This triggers the skin’s healing response, stimulating new collagen formation to help repair the damage. As the skin heals, damaged skin is sloughed away, revealing smoother and tighter-looking skin beneath it. This can be especially helpful for deep textural imperfections including wrinkles and acne scarring. In fact, JAMA Dermatology recognizes ablative laser treatments as an effective form of scar treatment.[11]Ablative laser treatments require considerable pre-treatment and post-treatment attention. A physician may prescribe an antiviral medication before and after the procedure as a precaution if you are prone to infections. Some treatments may require sedation, depending on the type of ablation and the treated area. After treatment, you can expect pain, swelling and discomfort for up to two weeks. You’ll also need to avoid unprotected sun exposure to prevent serious skin damage. [12]Non-Ablative Laser TreatmentUnlike standard ablative laser treatments, non-ablative laser treatments for skin tightening stimulate collagen production to improve skin texture without wounding the skin. Because this non-invasive skin resurfacing procedure is gentler on the skin, the recovery time is much shorter and less painful. Non-ablative skin tightening skin treatments may not offer the same level of results as ablative laser procedures, but over time they can result in smoother skin and a more even skin tone.Ultrasound for Skin TighteningMost of us are familiar with ultrasound's use in medical diagnostics and obstetrics, but ultrasound energy is also beneficial for keeping the skin firm and smooth. Ultrasound targets the lower layers of skin below the epidermis. During the procedure, ultrasound is transmitted through the skin to heat the skin at depths of up to 5mm. The gentle heat stimulates collagen production, resulting in firmer-looking skin. Targeting specific areas, ultrasound skin tightening rejuvenation treatments can improve elasticity in places where it’s often needed the most — the middle and lower face. When used on sagging skin in these areas, ultrasound treatments can offer a viable alternative to a mini-facelift.[13]In fact, a 2018 study published in the journal Plastic and Reconstructive Surgery evaluated the effectiveness of focused ultrasound on 50 adults with lower and mid-face sagging. After six months, participants were assessed by third-party evaluators and also by a self-assessment questionnaire. The evaluators saw improvements in 93% of the participants. About 85% of participants themselves saw positive changes in their skin, according to the self-assessment questionnaires.[14]The side effects of ultrasound treatments for skin tightening are often temporary. During the procedure, clients may experience some discomfort. Afterwards, redness, numbness, and slight bruising may occur for a short period.[15]Radiofrequency (RF) treatmentsLike ultrasound treatments, radiofrequency (RF) energy can be used to heat the skin in order to boost collagen production. RF treatments concentrate heat onto the upper layers of skin to reduce wrinkling and tighten minor sagging. A 2018 study published in the Annals of Dermatology found that three RF energy treatments performed over six weeks [16] on older adults resulted in significant wrinkle reduction. Another small study focused on the use of RF energy for facial contouring. Of the 11 participants in the study, 73% saw improvements in facial contours when RF was combined with electromagnetic treatments.[17]Radiofrequency treatments are available for use on the face, neck, and body and are performed in-office. Treatments can also be combined with other non-invasive aesthetic procedures, like microneedling and ultrasound to target multiple layers of skin. Because RF energy heats skin layers, side effects include burning and temporary pain.[18]LED Light TherapyThe sun’s ultraviolet rays are dangerous for unprotected skin, but not all light rays are harmful. In fact, light rays of different frequencies can actually have healing properties. LED light therapy harnesses red, blue, and near-infrared light to safely renew and firm damaged skin. LED light therapy not only stimulates collagen but also kills acne-causing bacteria that can trigger breakouts. Interestingly, NASA initially used LED light therapy aboard space shuttle missions to promote wound healing. In fact, a published study indicated that LED light therapy promoted skin healing in 40% of its participants.[20] Soon, researchers noticed that skin that was exposed to the therapy also appeared smoother. [19] Side effects are minimal when LED treatments are conducted in a dermatology office. Chemical PeelsChemical peels, also called chemexfoliation or derma-peeling, utilize a variety of chemical agents to exfoliate skin cells on the mid to outer layers of skin, encouraging new cell development and collagen synthesis. [21] Chemical peels fall into three categories based on strength:[22]
- Superficial peels that use mild acids to penetrate the outermost layers of skin.
- Medium peels use glycolic acid or trichloroacetic to remove the outer layers of skin and those right beneath the top layer.
- Deep peels that reach the middle layer of skin, using phenol or trichloroacetic acid to remove damaged cells.
03
At-Home Non-Invasive Skin Tightening Devices
Want to skip a trip to the dermatologist’s office? Some non-invasive treatments can be performed with at-home devices. LED Light TherapyAt-home LED light therapy devices come in various forms, from handheld wands to masks that fit over the entire face. Wands typically work well for targeting specific areas while LED masks work well for treating the full face. Instructions vary but most devices require consistent use for best results. The quality of devices can vary significantly so look for reviews and scientific data to validate your purchase. Some LED light can have negative impacts on your eyesight, so be sure to follow all safety instructions and wear protective eyewear. [28]MicroneedlingThe thought of at-home microneedling may give you pause, but at-home derma rollers are gentler and do not puncture the skin as deeply as in-office microneedling treatments. At-home derma rollers feature very short needles–usually about 0.15mm–compared to the larger 1.5mm needles you’re likely to see in office.[29] When these needles puncture the skin, they activate the skin’s natural healing response–telling the skin it’s time to make more collagen and new, fresh skin cells. This can help diminish signs of aging like fine lines and hyperpigmentation. As with most at-home cosmetic devices, quality can vary greatly between devices and manufacturers. Some needles, for example, are too short and barely penetrate past the first layer of skin. Additionally, because most devices roll across the face instead of vertically puncturing the skin like a stamp, using them incorrectly or too aggressively may result in injury. Cleaning your device thoroughly between uses is critical to preventing bacterial contamination. Microneedling may cause bleeding, bruising, and — though rare — can cause infection, swollen lymph nodes, and hyperpigmentation.[30]MicroneedlingThe thought of at-home microneedling may give some people pause. Luckily, the devices for at-home treatments are gentler than those meant for in-office use—an at-home microneedling device for skin-tightening looks akin to a miniature paint roller. The roller portion of the device contains tiny, delicate needles that gently penetrate the skin. A study into micro needling indicates that a 1.5mm needle works best, but this optimal size is typically reserved for in-office visits. For comfort, safety, and effectiveness at home, a 0.15mm is recommended.[29] When it comes to microneedling, a larger needle doesn’t necessarily produce better results.As with most at-home cosmetic devices, quality can vary greatly between devices and manufacturers. Some needles, for example, are too short and barely penetrate past the first layer of skin. Additionally, most devices roll across the face, the motion of which may cause excessive injury compared to in-office microneedling in which the needles are inserted and removed from the skin head-on. Microneedling may cause bleeding, bruising, and — though rare — can cause infection, swollen lymph nodes, and hyperpigmentation.[30]
03
At-Home Non-Invasive Skin Tightening Devices
Want to skip a trip to the dermatologist’s office? Some non-invasive treatments can be performed with at-home devices. LED Light TherapyAt-home LED light therapy devices come in various forms, from handheld wands to masks that fit over the entire face. Wands typically work well for targeting specific areas while LED masks work well for treating the full face. Instructions vary but most devices require consistent use for best results. The quality of devices can vary significantly so look for reviews and scientific data to validate your purchase. Some LED light can have negative impacts on your eyesight, so be sure to follow all safety instructions and wear protective eyewear. [28]MicroneedlingThe thought of at-home microneedling may give you pause, but at-home derma rollers are gentler and do not puncture the skin as deeply as in-office microneedling treatments. At-home derma rollers feature very short needles–usually about 0.15mm–compared to the larger 1.5mm needles you’re likely to see in office.[29] When these needles puncture the skin, they activate the skin’s natural healing response–telling the skin it’s time to make more collagen and new, fresh skin cells. This can help diminish signs of aging like fine lines and hyperpigmentation. As with most at-home cosmetic devices, quality can vary greatly between devices and manufacturers. Some needles, for example, are too short and barely penetrate past the first layer of skin. Additionally, because most devices roll across the face instead of vertically puncturing the skin like a stamp, using them incorrectly or too aggressively may result in injury. Cleaning your device thoroughly between uses is critical to preventing bacterial contamination. Microneedling may cause bleeding, bruising, and — though rare — can cause infection, swollen lymph nodes, and hyperpigmentation.[30]MicroneedlingThe thought of at-home microneedling may give some people pause. Luckily, the devices for at-home treatments are gentler than those meant for in-office use—an at-home microneedling device for skin-tightening looks akin to a miniature paint roller. The roller portion of the device contains tiny, delicate needles that gently penetrate the skin. A study into micro needling indicates that a 1.5mm needle works best, but this optimal size is typically reserved for in-office visits. For comfort, safety, and effectiveness at home, a 0.15mm is recommended.[29] When it comes to microneedling, a larger needle doesn’t necessarily produce better results.As with most at-home cosmetic devices, quality can vary greatly between devices and manufacturers. Some needles, for example, are too short and barely penetrate past the first layer of skin. Additionally, most devices roll across the face, the motion of which may cause excessive injury compared to in-office microneedling in which the needles are inserted and removed from the skin head-on. Microneedling may cause bleeding, bruising, and — though rare — can cause infection, swollen lymph nodes, and hyperpigmentation.[30]
04
At-Home Topical Products
Connective tissue cells called fibroblasts produce skin tightening proteins, like collagen and elastin, which give skin its flexibility and bounce. Fibroblasts also produce glycosaminoglycans (GAGs) such as hyaluronates, like hyaluronic acid, which maintain moisture within the skin, reinforcing skin’s flexibility and elasticity.[31],[32]Over time, fibroblasts slowly decrease their production of collagen, elastin, and hyaluronates. As this production slows, skin can become drier and lose its resilience and elasticity. In fact, after the age of 30, we lose approximately 1% of our natural collagen each year. With less collagen and hyaluronates, skin begins to wrinkle and sag.[33]Most at-home topical products for skin tightening aim to add or boost the production of these beneficial skin cell proteins in the hope of returning elasticity to the skin.[34]Retinol TopicalsRetinol, a form of vitamin A, is widely known for its wrinkle-reducing effects. Retinoids, the broader class of chemicals that retinol is part of, effectively reduce fine lines by boosting the skin’s natural collagen production. This results in a smoother skin texture, fewer visible lines, and tighter-looking skin. Retinol also encourages cell turnover, which rids the skin of damaged cells and reveals the newer cells underneath. [35] However, retinol has side effects that some people find difficult to tolerate, including severe skin dryness, significant irritation, and increased skin sensitivity. Most retinol products are not recommended for people who are pregnant or breastfeeding.[35]Creams and MoisturizersWhile anti-aging creams and moisturizers are non-invasive, cost-effective and easy to use, many fall short on their skin-tightening claims. A vast majority of creams and moisturizers on the market only hydrate the uppermost layers of skin, causing temporary hydration and wrinkle reduction. Unfortunately, they fail to penetrate the deeper layers of skin, which means they cannot make a long-term difference in skin firmness and elasticity. OneSkin’s OS-01 Topical SupplementsUnlike other creams and moisturizers, OneSkin’s Topical Supplements are powered by OS-01, a proprietary peptide that extends skin health at the molecular level. OneSkin’s Topical Supplements are tested for ingredient penetration, ensuring that the OS-01 peptide makes it beyond the skin surface to the areas of the skin that need it most. When compared to retinol in laboratory tests on human skin samples, OS-01 FACE increased the activity of biomarkers associated with collagen and hyaluronic acid production at similar levels, while reducing inflammation and aging biomarkers that retinol increased. [36] OS-01 FACE is clinically validated to improve barrier function*, while retinol may degrade the skin barrier and cause flaking, skin sensitivity, and irritation.Unlike aggressive or invasive skin tightening procedures, OS-01 Topical Supplements require no downtime or recovery period. In fact, the OS-01 peptide’s benefits are cumulative, so consistent use of OneSkin’s Topical Supplements over time results in continuous improvements in skin’s health. That’s because the OS-01 peptide is scientifically proven to reduce the accumulation of senescent cells** [36]–aged cells at the end of their life cycle that are a key trigger of skin aging. By reducing the accumulation of these cells, the OS-01 peptide targets the root cause of aging rather than just the surface symptoms, allowing it to deliver long-term results.OneSkin’s Topical Supplements offer measurable visible results, similar to many invasive and non-invasive skin tightening procedures, without any of the side effects. In a 12 week clinical study, OS-01 FACE improved skin elasticity in 90% of participants. Even better, OS-01 FACE was shown to improve firmness by 95.5%.**Shown in a 12-week clinical study**Shown in lab studies on human skin samples and/or cells
04
At-Home Topical Products
Connective tissue cells called fibroblasts produce skin tightening proteins, like collagen and elastin, which give skin its flexibility and bounce. Fibroblasts also produce glycosaminoglycans (GAGs) such as hyaluronates, like hyaluronic acid, which maintain moisture within the skin, reinforcing skin’s flexibility and elasticity.[31],[32]Over time, fibroblasts slowly decrease their production of collagen, elastin, and hyaluronates. As this production slows, skin can become drier and lose its resilience and elasticity. In fact, after the age of 30, we lose approximately 1% of our natural collagen each year. With less collagen and hyaluronates, skin begins to wrinkle and sag.[33]Most at-home topical products for skin tightening aim to add or boost the production of these beneficial skin cell proteins in the hope of returning elasticity to the skin.[34]Retinol TopicalsRetinol, a form of vitamin A, is widely known for its wrinkle-reducing effects. Retinoids, the broader class of chemicals that retinol is part of, effectively reduce fine lines by boosting the skin’s natural collagen production. This results in a smoother skin texture, fewer visible lines, and tighter-looking skin. Retinol also encourages cell turnover, which rids the skin of damaged cells and reveals the newer cells underneath. [35] However, retinol has side effects that some people find difficult to tolerate, including severe skin dryness, significant irritation, and increased skin sensitivity. Most retinol products are not recommended for people who are pregnant or breastfeeding.[35]Creams and MoisturizersWhile anti-aging creams and moisturizers are non-invasive, cost-effective and easy to use, many fall short on their skin-tightening claims. A vast majority of creams and moisturizers on the market only hydrate the uppermost layers of skin, causing temporary hydration and wrinkle reduction. Unfortunately, they fail to penetrate the deeper layers of skin, which means they cannot make a long-term difference in skin firmness and elasticity. OneSkin’s OS-01 Topical SupplementsUnlike other creams and moisturizers, OneSkin’s Topical Supplements are powered by OS-01, a proprietary peptide that extends skin health at the molecular level. OneSkin’s Topical Supplements are tested for ingredient penetration, ensuring that the OS-01 peptide makes it beyond the skin surface to the areas of the skin that need it most. When compared to retinol in laboratory tests on human skin samples, OS-01 FACE increased the activity of biomarkers associated with collagen and hyaluronic acid production at similar levels, while reducing inflammation and aging biomarkers that retinol increased. [36] OS-01 FACE is clinically validated to improve barrier function*, while retinol may degrade the skin barrier and cause flaking, skin sensitivity, and irritation.Unlike aggressive or invasive skin tightening procedures, OS-01 Topical Supplements require no downtime or recovery period. In fact, the OS-01 peptide’s benefits are cumulative, so consistent use of OneSkin’s Topical Supplements over time results in continuous improvements in skin’s health. That’s because the OS-01 peptide is scientifically proven to reduce the accumulation of senescent cells** [36]–aged cells at the end of their life cycle that are a key trigger of skin aging. By reducing the accumulation of these cells, the OS-01 peptide targets the root cause of aging rather than just the surface symptoms, allowing it to deliver long-term results.OneSkin’s Topical Supplements offer measurable visible results, similar to many invasive and non-invasive skin tightening procedures, without any of the side effects. In a 12 week clinical study, OS-01 FACE improved skin elasticity in 90% of participants. Even better, OS-01 FACE was shown to improve firmness by 95.5%.**Shown in a 12-week clinical study**Shown in lab studies on human skin samples and/or cells
Key Takeaways:
- Skin loses its elasticity over time, causing sagging and wrinkles.
- Invasive treatments for skin tightening — like facelifts — offer dramatic results, but the procedure comes with major risks, like nerve injury and infection.
- Creams and lotions can moisturize the skin, but most formulas don’t reach deeper skin layers for prolonged skin tightening effects.
- OneSkin’s Topical Supplements are gentle on skin, safe, and use a proprietary peptide to tighten skin and renew skin’s elasticity.
- OneSkin’s Topical Supplements offers many of the benefits of non-invasive in-office treatments, but with no downtime.
Key Takeaways:
- Skin loses its elasticity over time, causing sagging and wrinkles.
- Invasive treatments for skin tightening — like facelifts — offer dramatic results, but the procedure comes with major risks, like nerve injury and infection.
- Creams and lotions can moisturize the skin, but most formulas don’t reach deeper skin layers for prolonged skin tightening effects.
- OneSkin’s Topical Supplements are gentle on skin, safe, and use a proprietary peptide to tighten skin and renew skin’s elasticity.
- OneSkin’s Topical Supplements offers many of the benefits of non-invasive in-office treatments, but with no downtime.
References
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- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678000/
- https://www.plasticsurgery.org/cosmetic-procedures/thread-lift
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- [8] https://www.asds.net/skin-experts/skin-treatments/non-invasive-skin-tightening-treatments
- https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical-procedures/skin-tightening/
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- https://jamanetwork.com/journals/jamadermatology/article-abstract/1787836
- https://www.mayoclinic.org/tests-procedures/laser-resurfacing/about/pac-20385114
- https://pubmed.ncbi.nlm.nih.gov/24267423/
- https://journals.lww.com/prsgo/fulltext/2019/12000/use_of_micro_focused_ultrasound_for_skin.1.aspx
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695420/
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- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360959/
- https://www.americanboardcosmeticsurgery.org/are-radiofrequency-treatments-really-safe/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148276/
- https://pubmed.ncbi.nlm.nih.gov/11776448/
- https://www.aad.org/public/cosmetic/younger-looking/chemical-peels-overview
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122508/
- https://www.cdc.gov/botulism/general.html
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874868/
- https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/guide-botox-type-injectables/
- https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/guide-botox-type-injectables/
- https://www.fda.gov/consumers/consumer-updates/filling-wrinkles-safely
- https://www.health.harvard.edu/staying-healthy/led-lights-are-they-a-cure-for-your-skin-woes
- https://www.ncbi.nlm.nih.gov/pubmed/22256622
- https://www.fda.gov/medical-devices/aesthetic-cosmetic-devices/microneedling-devices#risks
- https://www.genome.gov/genetics-glossary/Fibroblast
- https://www.genome.gov/genetics-glossary/Fibroblast
- https://www.sciencedirect.com/science/article/pii/S0022202X15
- https://parjournal.net/article/view/3863
- https://www.health.harvard.edu/staying-healthy/do-retinoids-really-reduce-wrinkles
- Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
References
- https://www.asds.net/skin-experts/skin-treatments
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678000/
- https://www.plasticsurgery.org/cosmetic-procedures/thread-lift
- https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/facelift
- https://www.mayoclinic.org/tests-procedures/face-lift/about/pac-20394059
- https://www.mayoclinic.org/tests-procedures/face-lift/about/pac-20394059
- https://www.plasticsurgery.org/cosmetic-procedures/facelift/cost
- [8] https://www.asds.net/skin-experts/skin-treatments/non-invasive-skin-tightening-treatments
- https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical-procedures/skin-tightening/
- https://www.sciencedirect.com/topics/materials-science/cosmetics
- https://jamanetwork.com/journals/jamadermatology/article-abstract/1787836
- https://www.mayoclinic.org/tests-procedures/laser-resurfacing/about/pac-20385114
- https://pubmed.ncbi.nlm.nih.gov/24267423/
- https://journals.lww.com/prsgo/fulltext/2019/12000/use_of_micro_focused_ultrasound_for_skin.1.aspx
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695420/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929946/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360959/
- https://www.americanboardcosmeticsurgery.org/are-radiofrequency-treatments-really-safe/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148276/
- https://pubmed.ncbi.nlm.nih.gov/11776448/
- https://www.aad.org/public/cosmetic/younger-looking/chemical-peels-overview
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122508/
- https://www.cdc.gov/botulism/general.html
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874868/
- https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/guide-botox-type-injectables/
- https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/guide-botox-type-injectables/
- https://www.fda.gov/consumers/consumer-updates/filling-wrinkles-safely
- https://www.health.harvard.edu/staying-healthy/led-lights-are-they-a-cure-for-your-skin-woes
- https://www.ncbi.nlm.nih.gov/pubmed/22256622
- https://www.fda.gov/medical-devices/aesthetic-cosmetic-devices/microneedling-devices#risks
- https://www.genome.gov/genetics-glossary/Fibroblast
- https://www.genome.gov/genetics-glossary/Fibroblast
- https://www.sciencedirect.com/science/article/pii/S0022202X15
- https://parjournal.net/article/view/3863
- https://www.health.harvard.edu/staying-healthy/do-retinoids-really-reduce-wrinkles
- Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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