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Free shipping on orders over $79.00 USD

OS-01 LIP Mask

A deeply hydrating overnight lip mask powered by the OS-01 Peptide™ to restore smoother, fuller, healthier lips.01



  • Stimulates collagen, elastin, and hyaluronic acid production

  • 98% agreed their lips stayed hydrated for 8+ hours; 81% saw fewer wrinkles around the lips

  • Dermatologist tested, fragrance-free, safe for sensitive skin


*Applies clear. Due to natural ingredients, color in compact may vary slightly.

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For recurring orders, please keep your metal applicator and mirrored compact to use with future refills.

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How to apply OS-01 LIP

Using the metal applicator, apply a generous layer onto clean, dry lips as needed.

For a deep treatment, apply before bed and leave on overnight.

HOW OS-01 WORKS

The science to unlock your healthiest skin

Backed by over a decade of longevity research, the OS-01 Peptide™ targets the cells that speed up the visible signs of aging.02

OS-01 is scientifically proven to:

  • Support repair by reducing the buildup of senescent “zombie” cells
  • Improve how skin behaves, stimulating collagen and hyaluronic acid production
  • Build resilience, keeping your skin healthy and youthful as you age

Full ingredient list

Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan. *OS-01 PeptideTM

Your OS-01 LIP questions answered

OS-01 LIP Mask

4.6
Rated 4.6 out of 5 stars
Based on 125 reviews
Total 5 star reviews: 100 Total 4 star reviews: 9 Total 3 star reviews: 6 Total 2 star reviews: 8 Total 1 star reviews: 2
87%would recommend this product
125 reviews
  • BS
    Bhavani S.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask
    I recommend this product
    Rated 5 out of 5 stars
    18 seconds ago
    So far, so good!

    All the products I’ve tried from OneSkin are not “instant” in their benefits. Yet slowly but surely I like what I see and feel; & I believe in the science & integrity behind them. When I use this Lip Mask at night, my lips feel moisturized and soft - even when I wake. In the winter, I often get chapped lips, yet not this winter! And perhaps continuing may postpone a bit of aging for this already senior woman!

  • TN
    Trish N.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask
    I recommend this product
    Rated 5 out of 5 stars
    5 hours ago
    So far so good!

    Just started using the lip mask and my very dry lips already have a noticeable improvement after a few days. Would be interested in trying their skincare after this positive experience!

  • A
    Amy
    Reviewing
    OS-01 LIP Mask
    I recommend this product
    Rated 5 out of 5 stars
    13 hours ago
    5 Stars

    Absolutely amazing! My lips feel so much more hydrated. Would definitely buy again

  • JB
    Joanna B.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask
    Rated 3 out of 5 stars
    13 hours ago
    OS-01 Lip Mask

    This product is super moisturizing and creamy for the lips - love it.

    OneSkin
    5 hours ago

    Thank you so much for your wonderful feedback, Joanna! We are absolutely thrilled to hear that you're loving how super moisturizing OS-01 LIP Mask feels! It's so great that you're finding it gives your lips that perfect level of hydration and smoothness. We truly appreciate you taking the time to share your experience with us!

  • S
    Stacy
    Reviewing
    OS-01 LIP Mask
    I do not recommend this product
    Rated 2 out of 5 stars
    Yesterday
    2 Stars

    It is a nice consistency, but there were no instructions on how to use it as a mask and it doesn’t say whether it’s gluten-free or not

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
02 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1