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OS-01 LIP Duo

The only 24-hour system powered by the OS-01 Peptide™ to shield and restore your lips at the cellular level01.



  • OS-01 LIP SPF protects against UV and cellular aging by day

  • OS-01 LIP Mask promotes collagen, elastin, and hyaluronic acid at night


  • Dermatologist tested, fragrance-free, safe for sensitive skin


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OS-01 LIP SPF

Daytime:

Gently squeeze a small amount of OS-01 LIP SPF onto the applicator tip and apply a thin layer directly to lips prior to sun exposure.

OS-01 LIP Mask

Nighttime:

Using the metal applicator, apply a generous layer of OS-01 LIP Mask onto clean, dry lips before bed and leave on overnight.

*Applies clear. Due to natural ingredients, color in compact may vary slightly.

HOW OS-01 WORKS

The science to unlock your healthiest skin

Backed by over a decade of longevity research, the OS-01 Peptide™ targets the cells that speed up the visible signs of aging.02

OS-01 is scientifically proven to:

  • Support repair by reducing the buildup of senescent “zombie” cells
  • Improve how skin behaves, stimulating collagen and hyaluronic acid production
  • Build resilience, keeping your skin healthy and youthful as you age

Full ingredient list

OS-01 LIP SPF ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive Ingredients: Simmondsia, Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Beta-Sitosterol, Squalene, Lactic Acid, Palmitic acid. *OS-01 Peptide™

OS-01 LIP ingredients

Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan. *OS-01 Peptide™

OS-01 LIP Duo

4.8
Rated 4.8 out of 5 stars
Based on 111 reviews
Total 5 star reviews: 93 Total 4 star reviews: 12 Total 3 star reviews: 6 Total 2 star reviews: 0 Total 1 star reviews: 0
95%would recommend this product
111 reviews
  • DJ
    Dr Jo
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    5 Stars

    Perfect combo and so compact

  • CL
    Connie L.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    20 hours ago
    I love the way my lips feel

    After using for only 1 month, my lips are much more moisturized and are getting some fullness back. I love the way this feels!

  • LH
    Leila H.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    I’m loving this lip duo so far!

    I’ve only been using it for a week and I can feel a difference in hydration, firmness and fullness. Hoping for continued success! 🤞🏻

  • C
    Connie
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    5 Stars

    After only 1 month I can see a significant increase in moisture and plumpness

  • LL
    Laurie L.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 4 out of 5 stars
    5 days ago
    Lip Duo

    The Nighttime lip mask is outstanding and really helps moisturize my lips over night but I am disappointed with the spf lip treatment as it seems to dry out my lips very quickly.

    OneSkin
    19 hours ago

    Hi Laurie!

    Thank you so much for taking the time to share your experience with OS-01 LIP DUO! We're absolutely thrilled to hear that the nighttime lip mask is outstanding and really helping to moisturize your lips overnight - that's exactly what we hoped for when we developed this product to provide deep restoration while you sleep.

    Sometimes SPF formulations can feel drying, especially if lips are already dehydrated or if the climate is particularly harsh. Since you're already getting such great results from the nighttime mask, you might find that using it consistently helps create a better base for the OS-01 LIP SPF during the day. Some of our customers also find that applying the OS-01 LIP SPF in a thinner layer or reapplying it throughout the day rather than using one thick application helps maintain moisture.

    We're so grateful that OS-01 LIP RESTORE MASK is working so well for you, and we really value your honest feedback about the OS-01 LIP SPF. Your insights about how both products perform in your daily routine help us understand what's working and what we can continue to improve.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
02 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1