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The only 24-hour system powered by the OS-01 Peptide™ to shield and restore healthy looking and feeling lips.


  • OS-01 LIP Shield SPF 15+ defends against the 3 main drivers of lip aging by day

  • OS-01 LIP Mask deeply hydrates and helps support smoother, fuller-looking lips at night

  • Dermatologist tested, fragrance-free, suitable for sensitive skin

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  • Accepted National Eczema Association logo
  • Leaping bunny certified logo

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Ingredients that complement the OS-01 PeptideTM


Bisabolol

A chamomile-derived antioxidant that soothes irritation, calms signs of inflammation, and enhances ingredient absorption.


Vitamin E
A potent antioxidant that helps neutralize oxidative stress and supports daily repair from UV and environmental exposure.


Hyaluronic acid
A highly bioavailable form that delivers immediate hydration and long-lasting moisture retention for skin prone to dryness due to a thinner barrier and lack of natural sebum production.

How it works

Powered by the OS-01 Senescence Peptide™

Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.

DAY + NIGHT LIP DUO

4.6
Rated 4.6 out of 5 stars
Based on 896 reviews
Total 5 star reviews: 701 Total 4 star reviews: 84 Total 3 star reviews: 50 Total 2 star reviews: 32 Total 1 star reviews: 29
88%would recommend these products
896 reviews
  • LV
    Leslie V. B.
    Verified Buyer
    Reviewing
    DAY + NIGHT LIP DUO
    I recommend this product
    Rated 5 out of 5 stars
    11 hours ago
    Absolutely love the lip mask!

    I admit I was a little skeptical of the lip mask. I mean, how special could it be? Pretty darned special! My lips look and feel so much better in just a couple weeks. I love it!

    The lip color gloss is good too-nice, smooth application and looks nice on my lips. I'd like a different color, though because it's too light for me. It does feel fantastic though.

    I'm looking forward to continued improvement of my dry lips with this duo.

  • SC
    Serena C.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    My fav

    Loving this lip potion!

  • HB
    Heidi B.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD SPF 15+
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Lip gloss

    I love the applicator as well as the way the lip gloss feels on my lips. I wish there were more colors.

  • IC
    Irene C.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    In Love

    This is absolutely the most amazing lip product ever. I am completely in love with it and have been using it solely since my first application almost 6 months ago. My lips feel and look lush and full. My lips are smooth and feel great. I highly recommend this lip mask!

  • LJ
    Lala J.
    Verified Buyer
    Reviewing
    DAY + NIGHT LIP DUO
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    Love this duo

    I love the day night duo. The day product gives me a hint of color with the zinc oxide and my lips. Feels great/not heavy or sticky.

    The night mask is awesome. It adds moisture as I live in Colorado-very low humidity and I rarely have to put my lip balm on during the night.

Full ingredient list

OS-01 LIP SPF ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive ingredients: Simmondsia Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae rhamnoides (Sea Buckthorn) Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Lactic Acid, Octyldodecanol, Sorbitan Oleate, Alumina, Magnesium Oxide, Palmitic Acid, Iron oxides (CI 77491, CI 77492, CI 77499), Titanium Dioxide (CI 77891), Red 33 Lake (CI 17200), Red 7 Lake (CI 15850).

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

OS-01 LIP MASK ingredients

Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan. *OS-01 Peptide™