OS-01 HAIR peptide scalp serum
Reduce shedding and reactivate the hair growth cycle with our daily scalp serum, powered by the OS-01 Peptide™.01
- Nourishes the scalp, and promotes thicker, fuller, denser hair
- 81% showed a +40% improvement in hair density after 6 months
- Dermatologist tested, fragrance-free, safe for sensitive skin
1 month supply delivered every 1 month.
3 month supply delivered every 3 months.
6 month supply delivered every 6 months.
include dermaroller?
Free Coral Travel Bag + Travel OS-01 EYE with your first subscription
SUBSCRIPTION EXCLUSIVES
- Plastic neutral refillable packaging
- Exclusive early access to new products
- Earn 2x points for free products on all recurring orders
- Easily change, skip or cancel anytime
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Free shipping on orders over
Try it risk-free! 45 day money back guarantee.
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BENEFITS
Daily serum designed to nourish the scalp and reactivate your hair’s natural growth cycle01
Prevent a root cause of hair thinning
Prevents the accumulation of the cells that contribute to a disrupted hair growth cycle due to age, stress, and genetics.03-09
Scalp health
Safe for sensitive skin and promotes a healthy scalp microbiome, which can help foster healthy follicle function and hair density.01,09
Thicker, denser, fuller hair
Key ingredients complement the OS-01 peptide to promote strong, healthy hair.01
Not sure what type of hair loss you're experiencing? Take the quiz to find out how OS-01 HAIR might help.
CLINICAL DATA
Visible results, scientifically validated
81
of participants showed an increase in hair density (average +40%) after 6 months 01
78
participants showed an increase in hair thickness (average +43%) after 6 months 01
81
of participants observed overall improvements in their hair after 3 months 01
78
of participants said the overall health of their hair improved after 6 months 01
5-STAR REVIEWS
See why customers love OS-01 HAIR
"Just fantastic regrowth in areas where I desperately needed it." — LaDonna L., Beta Tester
"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester
"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester
The proof is in the pictures
What makes OS-01 HAIR unique?
- Model
- Proprietary ingredient
- No harsh side effects
- Lightweight & non-greasy
- Drug-free
- No prescription
- Supports scalp health
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OS-01 HAIR
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Prescription Hair Treatments
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Leading Supplement
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Leading Hair Serum
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Invasive Treatments (PRP, hair transplant, etc.)
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DIY Oils
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The science behind OS-01 HAIR
The science behind OS-01 HAIR
Your scalp ages just like the rest of your skin. But instead of lines and wrinkles, the accumulation of senescent cells impairs how your hair follicles function, leading to thinner, weaker strands over time.03-05
OS-01 HAIR was developed to target this issue at the root. It’s the first and only scalp serum powered by the OS-01 peptide, scientifically proven to reduce cellular senescence—a key driver of age-related hair thinning.02,09
When tested on senescence-induced cells in the lab, OS-01 HAIR significantly reduced senescence, reinforcing OS-01 HAIR’s potential to address one of the core biological processes behind age-related thinning and hair loss.03-09
Just like healthy skin supports better texture and tone, a healthier scalp sets the stage for stronger, fuller hair.
6 active ingredients complement the OS-01 peptide
How to Apply OS-01 HAIR
- We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
- Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose. Apply the serum directly to your scalp, starting at your natural part or hairline.
- Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
- Massage the serum into your scalp with your fingertips to ensure even distribution.
- Do not rinse. Style as usual.
- Use daily on dry or damp hair.
A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.
Your OS-01 HAIR questions answered
All Ingredients
Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.
OS-01 HAIR peptide scalp serum
- SAStephani A.Verified BuyerReviewingOS-01 HAIR peptide scalp serumI recommend this productRated 5 out of 5 stars2 days agoFeeling good
Do feel like I’ve noticed less “baldy” areas. Still too soon to tell.
- CCarlaReviewingOS-01 HAIRI recommend this productRated 5 out of 5 stars1 week ago5 Stars
A new OneSkin night time lip balm was on my wish list. Thanks.
- MJM J. D.Verified BuyerReviewingOS-01 HAIR peptide scalp serumI recommend this productRated 4 out of 5 stars1 week agoPatience & consistency
OS-01 seems to be helping hair growth a bit already (started 10-21-25). I see hairs filling in the "big nothing"!
Best results I had so far - this is third hair growth type of product I've tried. I'm sticking with it!!!
OneSkin1 week agoThat’s amazing to hear — thank you so much for sharing your experience! 🌱 We’re thrilled that OS-01 is helping you see progress already, especially after trying other products in the past. Consistency is key, and it sounds like you’re on a great track. Keep us posted on your journey — we love hearing updates like this!
- PPPatricia P.Verified BuyerReviewingOS-01 HAIRI recommend this productRated 4 out of 5 stars1 week agoI like it!
It seems like a very nice consistency and doesn't make my hair oily so it's possible to use it daily even though I only wash my hair twice a week. The only reason I didn't give it 5 stars is I have only used it for a week so I don't see any difference yet as it's too early to tell...but I do like it on my scalp and hair!
OneSkin1 week agoThank you for sharing your early experience with OS-01 HAIR, Patricia! 🌱 We’re so glad you’re enjoying the consistency and how lightweight it feels — that’s exactly what we aimed for so it can be used daily without weighing hair down.
It’s still early in your journey, but you’re off to a great start. In our clinical study, participants began noticing visible improvements around the 3-month mark, with 75% reporting new hair growth and 72% feeling their scalp was more nourished. After 6 months, 81% saw increased hair density and 78% saw greater hair thickness, alongside reduced shedding and fuller volume.
Consistency really pays off — the OS-01 peptide works beneath the surface to reactivate the natural hair growth cycle and support a healthier scalp microbiome over time. We can’t wait for you to see those results with continued use!
- KKKaren K.Verified BuyerReviewingOS-01 HAIRRated 3 out of 5 stars2 weeks agokeeping fingers crossed
really hoping to get the promised result. too early to tell yet, but am happy with the product so far.
OneSkin1 week agoHi Karen! Thank you for sharing your experience with OS-01 HAIR! We’re happy to hear you’re enjoying it so far and completely understand that visible results can take time. In our clinical studies, 81% of participants saw increased hair density and 78% experienced thicker hair after 6 months, with many also noticing fuller, healthier hair over time.
Consistency is key, and we’re excited for you to keep going and see those results build in the coming months.
Related Articles
Citations
01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.
02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03 Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259
04 Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318
05 Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269
06 Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/
07 Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic
08Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext
09 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
10 Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/
11 Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/
12 Shown in a 3 month beta test (brand led consumer perception study) with 22 participants and daily application of OS-01 HAIR (no dermaroller).