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OS-01 HAIR | 1 Month Supply Refill

4.2
4.2 out of 5
4.2 (46)
Up to 85% off

OS-01 HAIR | 1 Month Supply Refill

4.2
4.2 out of 5
4.2 (46)
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A breakthrough for thicker, denser, healthier hair.
01 Introducing the first scalp serum powered by OS-01, proven to target cellular senescence, a key contributor of hair loss and thinning.
02,03,06,07,08

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“By preventing senescent cells from releasing pro-aging factors, we can prevent healthy cells from becoming “zombies”–containing the spread of senescence and slowing down skin aging.” 3Science2

Alessandra Zonari, PhD
OneSkin Co-Founder & CSO 3Science2
OneSkin

OS-01 Peptide 3Science2

Our OS-01 formula targets aging at the cellular level, leaving skin nourished and resilient to daily stress 3Science2

Science Driven Innovation 3Science2

Utilizing advanced research to create effective skincare solutions. 3Science2

Inclusivity and Accessibility

Catering to a diverse range of skin types and needs.

Longevity and Sustainability

Focusing on long-term skin health and eco-friendly practices.

the 30-day one skin challenge

Instantly hydrated,deeply nourished skin 3Science2

93% agree their skin feels protected

87% agree skin looks visibly firmer

80% agree their skin appears to regenerate overnight

OUR APPROACH

Results that go beyond the lab 3Science2

7
Years of Research 3Science2

900
Peptides Screened

0
Patents & Publications

9000
Patents & Publications

OneSkin

Behind One Skin Longevity 3Science2

3Science2 As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning.

  1. Possible Increase of Skin’s Epidermal Thickness
  2. Increase of Key Biomarkers Associated with Cell Proliferation and Collagen Production
  3. May promote cell proliferation and collagen production, which can promote firmer, more renewed skin.
  4. Retinol Increases a Key Marker Associated with Skin Aging. OS-01 FACE Does Not.

How to apply OS-01 FACE and add to your routine 3Science2

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  • Dispense 1-2 pumps of OS-01 FACE onto fingers
  • Gently massage into skin on the face, neck, and hands
  • Use 2 times daily

3Science2

How it works 3Science2

Powered by the OS-01 Senescence Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03 3Science2

Frequently asked questions 3Science2

OS-01 HAIR | 1 Month Supply Refill

4.2
Rated 4.2 out of 5 stars
Based on 46 reviews
Total 5 star reviews: 30 Total 4 star reviews: 4 Total 3 star reviews: 8 Total 2 star reviews: 1 Total 1 star reviews: 3
72%would recommend this product
46 reviews
  • AH
    Amy H.
    Verified Buyer
    Reviewing
    OS-01 HAIR | 1 Month Supply Refill
    I recommend this product
    Rated 5 out of 5 stars
    23 seconds ago
    Working

    I feel that after 3 months of daily use, I’m seeing some results.

  • BN
    Brittany N.
    Verified Buyer
    Reviewing
    OS-01 HAIR | 1 Month Supply Refill
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    Awesome product!

    Helped with my postpartum hair loss!

  • HR
    Harley R.
    Verified Buyer
    Reviewing
    OS-01 HAIR | 1 Month Supply Refill
    I do not recommend this product
    Rated 1 out of 5 stars
    5 days ago
    Not that impressed

    I've been using your product for 9 months now and I don't really see any improvement,you boasted about a 85% rate of visible density and coverage...I just don't see it, it's not a cheap product Comparing with other products on the market..not sure if they work either.I will see the year out to maximise your recommendations to test the product entirely, I've used the product to a strict routine and had higher hopes,sadly do not see any improvement.. being a costly exercise.

    Harley .

    OneSkin
    3 days ago

    Hi Harley,Hi Harley,

    Thank you so much for taking the time to share such honest and detailed feedback after 9 months with OS-01 HAIR SCALP SERUM. We truly mean it when we say we appreciate your patience, your commitment to a strict routine, and your willingness to see the full year through. That kind of dedication says a lot about you, and we genuinely don't take it for granted.

    We can hear how frustrating and disheartening this has been — especially when you've invested so much, financially and personally, with such high hopes. Please know that your experience matters deeply to us, and we want to do everything we can to help before you reach that one-year mark.

    We do want to gently clarify one small thing: our clinical results show that 81% of participants saw a +40% improvement in visible hair density — the figure you may have seen quoted as 85% is a slight misremembering, but we completely understand how these numbers blur together! More importantly, those results came from a 6-month double-blind, independent, third-party clinical study where participants used OS-01 HAIR twice daily alongside a dermaroller once daily. Both elements together — the serum and the dermaroller — were part of the protocol that produced those impressive results. If the dermaroller hasn't been a consistent part of your routine, that could genuinely be a meaningful missing piece, as it helps the OS-01 peptide absorb more deeply into the scalp and has been shown to significantly optimize results.

    We also want to be honest with you: OS-01 HAIR is specifically designed to target cellular senescence in hair follicles — one of the key drivers of age-related hair thinning — but hair loss can have multiple contributing factors, and individual responses do vary. That doesn't mean we're giving up on finding something that works for you — quite the opposite.

    We would love to personally connect with you before your year is up. Whether it's reviewing your application technique, discussing the dermaroller, or just making sure you feel fully supported, we want to be in your corner. Please reach out to us at support@oneskin.co — we're here for you and we genuinely want your investment to feel worthwhile.

  • LF
    Lauren F.
    Verified Buyer
    Reviewing
    OS-01 HAIR | 1 Month Supply Refill
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Wonder Worker

    This product has helped to regrow my hair loss due to perimenopause.

  • JR
    Jennifer R.
    Verified Buyer
    Reviewing
    OS-01 HAIR | 1 Month Supply Refill
    Rated 3 out of 5 stars
    1 week ago
    Hair Serum

    I have been using the hair serum for 6 months, and the jury is still out! My hair is growing well, and strands seem a bit thicker, but not much regrowth on top where it is the thinnest. I did experience some shedding about month 4, but that has subsided.

    I will continue onward as I realize this is a long process!

    OneSkin
    6 days ago

    Hi Jennifer,

    Six months of consistency is no small thing — thank you for sticking with it and for sharing such an honest, detailed update. Your patience and self-awareness about this being a long process genuinely means a lot to us.

    The growth and strand thickness you're noticing are real, meaningful signs that the OS-01 peptide is doing its work at the follicle level. Early clinical results show that after 3 months, OS-01 HAIR increased hair density and thickness — so what you're feeling in the strands is consistent with what the science predicts. As for the crown area, we hear you, and we want to be honest with you: the top of the scalp, where hair is often the thinnest, tends to be the last area to respond visibly because follicle activity there has typically been suppressed the longest. That doesn't mean it won't come — it just means it's working on a longer timeline than the areas where growth was already closer to the surface.

    One thing worth mentioning: the clinical study was conducted with participants using OS-01 HAIR twice daily alongside a daily dermaroller, which significantly improves peptide absorption into the scalp. If you're not already using a dermaroller, it may be worth exploring — it could meaningfully accelerate the results you're working toward, particularly in that crown area.

    We'd love to connect with you directly to talk through your routine and make sure you're set up for the best possible outcome. Please feel free to reach out at support@oneskin.co — you've invested six months in this, and we want to make every one of them count.

    Thank you for trusting us, Jennifer. We're rooting for you.

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
02 Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05 https://academic.oup.com/bbb/article/72/12/3211/5941013 06 https://pubmed.ncbi.nlm.nih.gov/32522955/ 07 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886

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