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OS-01 EYE CREAM

20 mL / .67 fl oz

Hydrate and firm ultra-delicate skin with our daily eye cream, formulated with the highest concentration of the OS-01 Peptide™.01



  • Improves texture, tone, and elasticity

  • Increase collagen by an average of +130% in lab studies

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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White tube of 'ONE SKIN' topical supplement on a beige background

LIMITED TIME OFFER

Travel-size OS-01 BODY with your first subscription

$37 FREE

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  • Glamour Beauty & Wellness Award 2023 logo on a black background
  • Leaping bunny certified logo
  • Accepted National Eczema Association logo
  • Certified Plastic Neutral logo on a white background

OneSkin

BENEFITS

Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 03

Wrinkle reduction

Boosts collagen to visibly smooth lines and wrinkles.01

Firmness

Supports skin health for a firmer, more lifted appearance.01

Hydration

Strengthens the skin barrier to lock in moisture and keep skin hydrated.01

5-star reviews

See why customers love OS-01 EYE

“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.


"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.


"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.


"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.

CLINICAL DATA

Visible results, scientifically validated

96
of participants reported improved texture and tone 01

91
of participants reported improved radiance 01

88
of participants showed improved hydration 01

86
of participants had improved elasticity 01

Getting started with OS-01 EYE

Follow these easy steps for optimal results

  • Dispense 1 pump onto tip of finger
  • Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.05,06

All Ingredients

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

02 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

03 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

06 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 EYE CREAM

4.7
Rated 4.7 out of 5 stars
Based on 1,722 reviews
Total 5 star reviews: 1.4k
Total 4 star reviews: 183
Total 3 star reviews: 55
Total 2 star reviews: 26
Total 1 star reviews: 24
94%would recommend these products
1,722 reviews
  • CT
    catherine t.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 5 out of 5 stars
    15 hours ago
    Great

    Great

  • AF
    Angie F.
    Verified Buyer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 4 out of 5 stars
    22 hours ago
    Eye cream

    it feels nice and light and doesn't make my eyes water when I use it.

    OneSkin
    5 minutes ago

    Hi Angie! Thank you so much for your wonderful 4-star feedback about OS-01 EYE! We're really glad to hear that you're enjoying how light and comfortable it feels - that kind of positive experience really means the world to all of us at OneSkin!

    We really appreciate you sharing that the eye cream works so well for your eyes without any irritation. The fact that it feels nice and light while being gentle on your delicate eye area is exactly the kind of everyday performance we hope our customers experience.

    Thank you for taking the time to leave a review about OS-01 EYE - your feedback truly means so much to us!

  • MA
    Mark A.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    Give it a Try

    The OS-01 Eye lotion provides eye dryness care. The price is high but the application and lotion are great.

    OneSkin
    4 minutes ago

    Hi Mark! Thank you so much for your wonderful 4-star feedback about OS-01 EYE! We're absolutely thrilled to hear that you're enjoying the application and the lotion itself - that kind of positive experience really means the world to all of us at OneSkin!

    We really appreciate your honesty about the price point. We're glad that despite the investment, you're finding the quality of both the application and the product itself to be worth it. That kind of feedback helps us know we're delivering real value to our customers.

    Thank you for taking the time to share your thoughts about your OS-01 EYE experience - your 4-star review truly means so much to us!

  • MN
    Margaret N.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    OS-01 EYE Refill

    I love this no fuss, no force, easy screw-in refill... 2 seconds 2 go!

    The content, of course, is next level.

    Grateful.

    OneSkin
    2 days ago

    Hi Margaret! Thank you so much for your wonderful 5-star feedback about OS-01 EYE! We're absolutely thrilled to hear that you're loving the refill system - that kind of enthusiastic response really means the world to all of us at OneSkin!

    It's fantastic that you appreciate how simple and convenient the refill design is! The fact that you're getting it done in just 2 seconds shows exactly how we hoped the no-fuss, easy screw-in refill would work in real life - making it effortless to keep your routine going without any hassle.

    And we're so grateful for your appreciation of the content itself! Knowing that you find it next level and that you're experiencing such great results with OS-01 EYE is exactly the kind of feedback that shows how our science-backed approach to the delicate eye area really delivers.

    Your combination of loving both the convenience of the refill system and the quality of the product itself is exactly the kind of thoughtful approach to skincare that we hoped our refill option would support!

    Thank you for taking the time to share such encouraging feedback about your OS-01 EYE Refill experience - your 5-star review truly means so much to us!

  • CR
    Christine R.
    Verified Buyer
    Reviewing
    OS-01 EYE Topical Supplement Refill
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    Great eye supplement

    Very soothing and easy to apply.