This is a carousel. Use Next and Previous buttons to navigate

This is a carousel. Use Next and Previous buttons to navigate

Save 15% on limited edition sets. Shop now.

Subscribe & save 15%

Free shipping on orders over $79.00 USD

OS-01 BODY MOISTURIZER

Size: 250 mL

Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 PeptideTM and OneSkin Longevity ScienceTM.01



  • Improves skin texture, appearance, and hydration

  • Strengthens the skin barrier by up to +41%

  • Dermatologist tested, fragrance-free, safe for sensitive skin

SAVE 15% EVERY ORDER
  • Exclusive early access to new products
  • Earn 2x points on all recurring orders
  • Easily change, skip or cancel anytime
White cylindrical container with black lid labeled 'One Skin' on a beige background

LIMITED TIME OFFER

Travel-size OS-01 EYE with your first subscription

$38 FREE

✭ You’re earning 89 points with OneSkin Loyalty Program ✭

OneSkin

Free shipping on orders over $79.00 USD

OneSkin

Try it risk-free for 30 days!

OneSkin

You’re earning [potential_points] points with the OneSkin Loyalty Program

  • Certified Plastic Neutral logo on a white background
  • Leaping bunny certified logo
  • Accepted National Eczema Association logo

OneSkin

BENEFITS

Nourishing body moisturizer and targeted treatment for thin, crepey skin

Smooth texture

Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01

Deep hydration

Replenishes and locks in hydration to keep skin soft, plump, and nourished.01

Barrier support

Fortifies the skin barrier to protect against daily stressors and moisture loss.01

5-STAR REVIEWS

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

CLINICAL DATA

Visible results, scientifically validated

93
of participants reported improved hydration 01

70
of participants reported improved appearance 01

70
of participants reported improved texture 01

41
Improvement in skin barrier function was measured 01

Getting started with OS-01 BODY

Follow these easy steps for optimal results

  • Apply to arms, legs, chest, back, and stomach
  • Massage until absorbed
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

All Ingredients

Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide

Citations

01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 BODY MOISTURIZER

4.7
Rated 4.7 out of 5 stars
Based on 3,657 reviews
Total 5 star reviews: 2.9k
Total 4 star reviews: 456
Total 3 star reviews: 189
Total 2 star reviews: 63
Total 1 star reviews: 58
92%would recommend these products
3,657 reviews
  • PC
    Pamela C.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    OS-O1 Body Moisturizer

    Love it so far. Want to give it 12 weeks to see if it improves the crepey texture on my arms and legs. But I love that it’s easy to use non greasy and unscented!!!

  • JW
    Jori w.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    18 hours ago
    Body cream

    I definitely notice when I forget to apply this cream daily.

    I’m an older client but can attest to a reduction of wrinkles on my arms and legs .

    5 star

  • AM
    Anna M. D.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Yep - it’s really good

    I was skeptical - I was proven wrong! Awesome body cream. Go for it!

  • C
    Claire
    Verified Reviewer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    Pretty good

    I like the product, do not like the delivery. Plastic container, and it stops pumping out with about 1/4th left in the bottle, so I have to

    Leave it open and upside down to get the rest out.

    Please make a jar instead that is of glass.

    OneSkin
    1 hour ago

    Hi Claire!

    Thank you so much for taking the time to share your feedback about OS-01 BODY MOISTURIZER — we're glad to hear that you're enjoying the product itself!

    We completely hear you on the packaging frustration. It's disappointing when you're unable to access the full amount of product you've purchased, and we understand how annoying it must be to have to work around the pump design to get those last bits out. Your suggestion about a glass jar format is really valuable feedback, and we appreciate you taking the time to share what would work better for you.

    Your input about packaging preferences genuinely helps us understand what our customers are looking for, and we'll make sure this gets passed along to our team as we continue to develop our product offerings.

    Thank you for choosing OneSkin, and we're sorry the delivery format didn't fully meet your expectations!

  • SW
    Sandy W.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Love it!

    Perfect consistency. Body Moisturizer is not thick or sticky.