A CLINICAL STUDY
Split Face Study to Evaluate the Effects of OS-01 FACE and the OS-01 Peptide
A third-party research organization with no affiliation to OneSkin conducted a 12-week split-face double-blind clinical study to evaluate the effects of OS-01 FACE and the OS-01 peptide, which has been published in the Journal of Cosmetic Dermatology.
The Findings
OS-01 FACE significantly improves skin barrier function, texture, and radiance, and reduces the appearance of fine lines and wrinkles. Participants also perceived improvements in skin hydration, smoothness, radiance, and overall appearance.
The OS-01 peptide significantly improves skin barrier function and skin texture.
Shattering industry norms (in other words, business as usual)
3 unique attributes of the study:
Given that OS-01 FACE is packed with bioactive ingredients that have their own benefits, comparing it against an identical, peptide-free version really put OS-01 in the spotlight. This method isn’t something you see every day in the skin care industry, making our study not only rigorous, but also quite unique.
- Model
- OS-01 Peptide
- Pracaxi Oil
- Andiroba Oil
- Oleic Pau Mulato Extract
- Naicinamide
- Allantoin
- 3 sizes of hyalronic acid
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OS-01 FACE
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VEHICLE FORMULATION
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Methods of Analysis
Three methods of analysis
1. Instrumental analysis:
- Vapometer to measure skin barrier function
- Antera 3D to measure skin texture and wrinkles
- VISIA imaging software to measure skin radiance
2. Expert clinical grade evaluation: Blinded experts (who don’t know which areas of the skin received OS-01 FACE or the vehicle formulation) grade high resolution images of participants’ skin before and after treatment
3. Self-perception questionnaire: Participants report the effects they observed before and after treatmentInstrumental analyses were used whenever possible, which unlike expert clinical evaluation and self-perception offer completely objective results. Of course, some results can’t be measured and the way people feel about their skin matters too. That’s why we included expert analysis and personal perception results as well.
Split Face Study to Evaluate the Effects of OS-01 FACE and the OS-01 Peptide
Smoother, more radiant skin with a stronger barrier—all from the OS-01 peptide
By comparing improvements between skin treated withOS-01 FACEversus the vehicle formulation, the investigators found that the OS-01 peptide:
- Significantly improves barrier function and protects the skin from dehydration
- Significantly improves skin texture
- Improves skin radiance and reduces the appearance of fine lines and wrinkles
Cinical Efficacy Meets Scientific ProofThe improvement in barrier function is consistent with data that our scientists have collected in the lab, showing that the OS-01 peptide increases skin’s epidermal thickness — a key factor in barrier strength and function. (01)Additionally, the improvement in skin texture aligns with what’s happening at the cellular level, since our scientists have determined that the OS-01 peptide increases key biomarkers associated with collagen and hyaluronic acid production (01), which contribute to more even skin texture.Finally, improvements in radiance and wrinkles were likely due to the fact that the OS-01 peptide has been shown to reduce the levels of senescence in skin, a central hallmark of aging. (01)(01)Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
Real life results beyond the lab
Real results, zero editing
The OS-01 peptide is proven to help improve texture, enhance radiance, and reduce the appearance of fine lines and wrinkles.
1. Wrinkles
2. Texture
3. Radiance
