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OS-01 LIP Mask, Recurring

4.8
4.8 out of 5
4.8 out of 5
(94)
Open compact with beige cream on a white background
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
Open compact with beige cream on a white background
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring
OS-01 LIP Mask, Recurring

A deeply hydrating overnight lip mask powered by the OS-01 Peptide™ to restore smoother, fuller, healthier lips.



  • Stimulates collagen, elastin, and hyaluronic acid production

  • 98% agreed their lips stayed hydrated for 8+ hours; 100% saw fewer wrinkles around the lips

  • Dermatologist tested, fragrance-free, safe for sensitive skin


*Applies clear, but due to natural ingredients, color in compact may vary slightly between products

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Clean + Safe Ingredients

Made with vegan, sustainably sourced ingredients. OS-01 LIP SPF is non-comedogenic (non-pore clogging), 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives, and solvents.

  • Accepted National Eczema Association logo

  • Leaping bunny certified logo

  • Accepted National Eczema Association logo

  • Leaping bunny certified logo

  • Accepted National Eczema Association logo

  • Leaping bunny certified logo

OneSkin

Benefits

Delivers immediate hydration and advanced protection from 3 types of aging for visibly healthier, more resilient lips.1

100% mineral protection

Non-nano zinc oxide prevents UV-induced damage including inflammation and collagen loss.1

Soothing + nourishing

92% agreed it feels instantly moisturizing upon application, keeping lips healthy and hydrated.1

Fuller, smoother lips

Boosts a key elastin production biomarker by +47%, helping preserve volume and minimizing the appearance of lines and wrinkles.1

5-star reviews

See why customers love OS-01 LIP SPF

“My lips appear plumper and deeper in color in an incredibly healthy and youthful appearance. I have tried high end and low end brands and nothing compares to the efficacy of this product.” – Caroline W.

"My lips have constantly felt softer. And I also had a special case because I had an eczema patch on my lips before I started using this product, and I was worried it would make it worse but it actually made it better! My eczema patch cleared up after a couple weeks of use. Huge fan of this product overall.” – Victoria Z.

“This definitely helped my chronically dry and chapped lips. I would make this my go to moving forward.” – Adam P.

CONSUMER PERCEPTION DATA

Real results that speak volumes

92%
agree it delivers immediate hydration and moisture 01
88%
agree it makes their lips feel soothed and protected 01
84%
agree their lips felt nourished after 2 weeks 01
78%
agree it provides long-lasting hydration and moisture 01

5 active ingredients that complement the OS-01 peptide

see all ingredients

Vitamin E

Provides protection against environmental stressors and barrier support, keeping lips soft and supple.

Vitamin C

A highly stable form of vitamin C (Tetrahexyldecyl Ascorbate), this antioxidant penetrates deeply to brighten and improve collagen production.

Bisabolol

A soothing anti-inflammatory active known to enhance the skin’s ability to heal—even in harsh conditions.

Centella Asiatica Extract

Helps repair and fortify the delicate lip barrier, promoting collagen synthesis for plumper, healthier-looking lips.

Sea Buckthorn Oil

Packed with antioxidants, Omega fatty acids, and vitamin C, this oil rejuvenates dry lips, restores elasticity, and helps protect against environmental damage.

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

Discover the Science

All ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive Ingredients: Simmondsia, Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Beta-Sitosterol, Squalene, Lactic Acid, Palmitic acid. *OS-01 Peptide

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

OS-01 LIP Mask, Recurring

Write a Review (Opens in a new window)
94 reviews
  • JS
    Jenna S.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    22 seconds ago
    Best there is

    From the first night onward, this lip mask is a game changer. My husband has made a habit of giving me a good night kiss AFTER I’ve put it on so he can steal a little. It’s basically the fountain of youth for your lips.

    Was this helpful?
  • MM
    Myrna M.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Very Happy

    First time user. It’s been 6 weeks since I’ve been using the lip mask and I’m very happy with it. My lips are moist and no longer are dry around them. I’ll continue to use this product.

    Was this helpful?
  • SK
    Susannah K.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    None better

    Lip mask is my outstanding product of a lifetime.

    This product has worked better for me than any other lip product, or face product for that matter, over my lifetime.

    Since middle school, I have spent decades using lip balms which I now know, probably started a cycle of dehydrating my lips.

    Three days into OneSkin lip mask, the cycle was broken, never to be restarted. I use sunscreen during the day, lip mask at night. And I no longer feel the constant need to apply lip balm.

    I would love a peek at my histology before and after this last year of use, but I’m guessing , there are verifiable positive changes.

    I hope it works this well for everyone.

    It’s the product I never thought was possible.

    Thanks OneSkin. (Women in science! Yay!)

    Was this helpful?
  • RG
    Renee G.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    It works

    Best I’ve tried so far!

    Was this helpful?
  • S
    selena
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    5 Stars

    A staple in my routine, love the way it glides on

    Was this helpful?
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Citations

1 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
2 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
3 Zonari A.,et al.Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation.J Cosmet Dermatol.2024; 23: 2135-2144. doi:10.1111/jocd.16242