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OS-01 LIP Mask, Recurring

4.8
4.8 out of 5
4.8 (78)

A deeply hydrating overnight lip mask powered by the OS-01 Peptide™ to restore smoother, fuller, healthier lips.



  • Stimulates collagen, elastin, and hyaluronic acid production

  • 98% agreed their lips stayed hydrated for 8+ hours; 100% saw fewer wrinkles around the lips

  • Dermatologist tested, fragrance-free, safe for sensitive skin


*Applies clear, but due to natural ingredients, color in compact may vary slightly between products

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  • Accepted National Eczema Association logo
  • Leaping bunny certified logo

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Benefits

Delivers immediate hydration and advanced protection from 3 types of aging for visibly healthier, more resilient lips.01

100% mineral protection

Non-nano zinc oxide prevents UV-induced damage including inflammation and collagen loss.01

Soothing + nourishing

92% agreed it feels instantly moisturizing upon application, keeping lips healthy and hydrated.01

Fuller, smoother lips

Boosts a key elastin production biomarker by +47%, helping preserve volume and minimizing the appearance of lines and wrinkles.01

5-star reviews

See why customers love OS-01 LIP SPF

“My lips appear plumper and deeper in color in an incredibly healthy and youthful appearance. I have tried high end and low end brands and nothing compares to the efficacy of this product.” – Caroline W.

"My lips have constantly felt softer. And I also had a special case because I had an eczema patch on my lips before I started using this product, and I was worried it would make it worse but it actually made it better! My eczema patch cleared up after a couple weeks of use. Huge fan of this product overall.” – Victoria Z.

“This definitely helped my chronically dry and chapped lips. I would make this my go to moving forward.” – Adam P.

CONSUMER PERCEPTION DATA

Real results that speak volumes

92
agree it delivers immediate hydration and moisture 01

88
agree it makes their lips feel soothed and protected 01

84
agree their lips felt nourished after 2 weeks 01

78
agree it provides long-lasting hydration and moisture 01

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

All ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive Ingredients: Simmondsia, Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Beta-Sitosterol, Squalene, Lactic Acid, Palmitic acid. *OS-01 Peptide

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

OS-01 LIP Mask, Recurring

4.8
Rated 4.8 out of 5 stars
Based on 78 reviews
Total 5 star reviews: 67 Total 4 star reviews: 8 Total 3 star reviews: 1 Total 2 star reviews: 1 Total 1 star reviews: 1
96%would recommend this product
78 reviews
  • LC
    Leslee C. P.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    21 seconds ago
    Does it hydrate?

    Yes it does!!! I’ve been experiencing autoimmune issues and it affected my lips and surrounding skin. I’ve been using this product for two months and am very pleased!

  • IC
    Irene C.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    In Love

    This is absolutely the most amazing lip product ever. I am completely in love with it and have been using it solely since my first application almost 6 months ago. My lips feel and look lush and full. My lips are smooth and feel great. I highly recommend this lip mask!

  • LG
    lori g.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Finally No Dry Lipd

    I've been trying different lip stuff for my lips for decades. Finally tried the os-01 lip mask and got relief. My lips are moist and even thru the horrible winter of 25-26 didn't get chapped.

  • HM
    H M.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    The absolute best lip mask!

    I've been using this lip mask for 2 months every night before I go to bed. I've not used a better lip mask that is thick enough that stays on my lips all night. I have not had one chapped lip, dryness or cracked lips since I've been using this product. I have it on auto delivery and never want to run out. I also use their moisturizing cream and it is excellent as well.

  • KF
    Kelly F.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    One Skin has the best 2 lip products.

    I literally can’t live without their OS-01 peptide lip mask. I use lip liner and lipstick all day, every day and my lips hurt at night. Just a bit of their lip mask or lip spf (which I use in the sun and at night) and my lips feel great! I’ll always have both products in my purse or beach bag.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
02 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03 Zonari A.,et al.Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation.J Cosmet Dermatol.2024; 23: 2135-2144. doi:10.1111/jocd.16242