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OS-01 Face Topical Supplement, 15ml

4.7
4.7 out of 5
4.7 out of 5
(6,502)
Skincare bottle labeled 'ONE SKIN' on a beige background
Skincare bottle labeled 'ONE SKIN' on a beige background

OS-01 FACE Topical Supplement, 15 mL (Limited Edition) 


While supplies last


The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.




  •  Developed by longevity scientists


  •  Safe and clean


  •  For all skin types


  •  Vegan & Cruelty-Free


  • Flagrance free Fragrance-Free

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Free shipping on orders $79+

Try it risk-free for 30 days!

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OS-01 Face Topical Supplement, 15ml includes:
  • Slip Pillow Case Slip Pillow Case
  • Slip Scrunchie Slip Scrunchie
  • White bottle with black pump and 'One Skin' logo on a beige background OS-01 BODY MOISTURIZER
  • Skincare bottle labeled 'One Skin' on a beige background OS-01 FACE MOISTURIZER
  • Clear bottle with black pump and 'One Skin' label on a light beige background OS-01 EYE CREAM
  • An open black One Skin cushion foundation compact, showing the warm beige foundation powder and the built-in mirror inside the lid, set against a clean off-white background. OS-01 LIP MASK
Clean + Safe Ingredients

Our products are non-comedogenic (non pore-clogging), 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives, and solvents. We prioritize the use of key ingredients that ensure a safe and effective formulation, delivering the best results for your skin needs.

“By preventing senescent cells from releasing pro-aging factors, we can prevent healthy cells from becoming “zombies”–containing the spread of senescence and slowing down skin aging.” 3Science2

Alessandra Zonari, PhD
OneSkin Co-Founder & CSO 3Science2
OneSkin

OS-01 Peptide™ 3Science2

Our OS-01 formula targets aging at the cellular level, leaving skin nourished and resilient to daily stress 3Science2

Science Driven Innovation 3Science2

Utilizing advanced research to create effective skincare solutions. 3Science2

Inclusivity and Accessibility

Catering to a diverse range of skin types and needs.

Longevity and Sustainability

Focusing on long-term skin health and eco-friendly practices.

the 30-day one skin challenge

Instantly hydrated,deeply nourished skin 3Science2

93% agree their skin feels protected

87% agree skin looks visibly firmer

80% agree their skin appears to regenerate overnight

OUR APPROACH

Results that go beyond the lab 3Science2

7+
Years of Research 3Science2
900+
Peptides Screened
0%
Patents & Publications
9000
Patents & Publications
OneSkin

Behind One Skin Longevity 3Science2

3Science2 As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning.

  1. Possible Increase of Skin’s Epidermal Thickness
  2. Increase of Key Biomarkers Associated with Cell Proliferation and Collagen Production
  3. May promote cell proliferation and collagen production, which can promote firmer, more renewed skin.
  4. Retinol Increases a Key Marker Associated with Skin Aging. OS-01 FACE Does Not.

3Science2

6 active ingredients that complement the OS-01 Peptide™ 3Science2

3Science2

Pracaxi Oil 3Science2

Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial 3Science2

Andiroba Oil

A seed oil that promotes healthy collagen and minimizes the effects of inflammation

Niacinamide

A form of vitamin B that improves skin texture by promoting

Oleic Pau Mulato Extract

An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports

Allantoin

A skin-conditioning molecule that moisturizes and soothes irritated skin

Hyaluronic Acid

A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin

How to apply OS-01 FACE and add to your routine 3Science2

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  • Dispense 1-2 pumps of OS-01 FACE onto fingers
  • Gently massage into skin on the face, neck, and hands
  • Use 2 times daily

3Science2

How it works 3Science2

Powered by the OS-01 Senescence Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03 3Science2

Frequently asked questions 3Science2

How long will my Topical Supplement last?

We estimate the 50 ml bottle of OS-01 FACE will last approximately 1-3 months when used as directed. 

How does OS-01 FACE compare to retinol?

This is an example of a response that you might give. It's good to be as thorough as possible in responses as that has a tendency to improve trust overall.

How should retinol be used with OS-01 FACE?

This is an example of a response that you might give. It's good to be as thorough as possible in responses as that has a tendency to improve trust overall.

How do I assemble my FACE refill once I receive it?

This is an example of a response that you might give. It's good to be as thorough as possible in responses as that has a tendency to improve trust overall.

OS-01 Face Topical Supplement, 15ml

6,502 reviews
  • CG
    Catherine G.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Excellent refill

    Very clever refill packaging which is very easy to insert into original container.

  • EH
    Ericka H.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Lovely results with consistency

    I've been using the Oneskin face cream on and off since it came out. I noticed AMAZING results within the first 90 days of using it every day. My skin looked more refined, pores looked smaller, skin looked firmer and I had less fine lines overall. I only have 2 negatives that have kept me from using it during the day and consistently. First, it's not moisturizing enough for my more mature, dry skin to be used on it's own. I always have to load up on humectants or moisturizing serums prior to use and I always have to top it with another moisturizer. Second, my last shipment started to pill or ball up on my skin after it had been absorbed. I have not changed any of the skincare I use with it but I even tried it just on its own and still had the same pilling. Because of these two reasons, I only use it at night now and do swap it out with a prescription retinoid every other night. I'm really hoping this newest refill does not pill!

  • CB
    Catherine B.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Worth it.

    Liked it enough to subscribe, which I almost never do with any product. One Skin is awesome.

  • MO
    Magdalen O.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Face Refill

    Less bulky without the shell. Good product.

  • LB
    Lyndsay B.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Great moisturizer

    My skin is so much healthier than when I started using OS FACE. I don't have dry skin issues anymore, and the moisturizer works well under powder makeup. People tell me all the time that I look younger than I am--can't say it's just from my moisturizer, but I think that's helping!

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
02 Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05 https://academic.oup.com/bbb/article/72/12/3211/5941013 06 https://pubmed.ncbi.nlm.nih.gov/32522955/ 07 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886

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