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HAIR
BENEFITS
Daily serum designed to nourish the scalp and reactivate your hair’s natural growth cycle1
Prevent a root cause of hair thinning
Prevents the accumulation of the cells that contribute to a disrupted hair growth cycle due to age, stress, and genetics.03-09
Scalp health
Safe for sensitive skin and promotes a healthy scalp microbiome, which can help foster healthy follicle function and hair density.01,09
Thicker, denser, fuller hair
Key ingredients complement the OS-01 Peptide™ to promote strong, healthy hair.1
CLINICAL DATA
Visible results, scientifically validated
5-STAR REVIEWS
See why customers love OS-01 HAIR
"Just fantastic regrowth in areas where I desperately needed it." — LaDonna L., Beta Tester
"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester
"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester
The proof is in the pictures
What makes OS-01 HAIR unique?
- Model
- Proprietary ingredient
- No harsh side effects
- Lightweight & non-greasy
- Drug-free
- No prescription
- Supports scalp health
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OS-01 HAIR
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✓
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✓
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✓
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✓
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Prescription Hair Treatments
- ✓
- X
- X
- X
- X
- X
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Leading Supplement
- X
- ✓
- N/A
- ✓
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- X
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Leading Hair Serum
- X
- ✓
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Invasive Treatments (PRP, hair transplant, etc.)
- X
- X
- N/A
- ✓
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- N/A
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DIY Oils
- X
- ✓
- X
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6 active ingredients complement the OS-01 peptide
Panax Ginseng Root extract
Stimulates blood flow and improves circulation to the scalp, providing hair follicles with better access to nutrients.
Fisetin
A naturally occurring flavonoid with strong antioxidant and anti-inflammatory properties, which can help protect hair follicles from oxidative stress and inflammation—two factors that contribute to hair thinning and loss.
Oryza Sativa (rice) bran water
A nutrient and antioxidant rich extract used to strengthen and smooth hair, and enhance shine and manageability. It may also provide mild exfoliation to the scalp, helping promote a healthy environment for hair growth.
Sunflower Sprout extract
Rich in antioxidants and nutrients such as vitamins A, D, and E to help protect the hair and scalp from UV-induced oxidative stress, and maintain hair density, vitality, and overall health.
Biotin
Well-known for its ability to support keratin production, strengthen the hair shaft, and reduce breakage, promoting fuller, thicker hair.
Inulin and Alpha-Glucan Oligosaccharide
Prebiotic ingredients that support scalp health, essential for strong, resilient hair growth. Also improves scalp hydration, enhancing moisture retention and reducing dryness and irritation.
Getting started with OS-01 HAIR
Follow these easy steps for optimal results
- Apply 1 mL of serum (approximately 2 full droppers) directly to your scalp and massage in with fingertips
- Leave on, do not rinse
- Use up to 2 times daily
Your OS-01 HAIR questions answered
Can I use this serum alongside minoxidil or other hair treatments and products?
OS-01 HAIR complements other medical-grade treatments and can be used alongside other products as well. We always recommend applying OS-01 HAIR first and patch-testing when using other products to ensure the combination of all products works well for you.
If you are currently using a product containing Minoxidil please DO NOT completely stop use of that product or treatment. We recommend using OS-01 HAIR in combination with the product containing Minoxidil. You can start using OS-01 HAIR immediately, but do not stop Minoxidil abruptly. If you plan to discontinue Minoxidil, we recommend tapering off gradually over a few weeks or months to minimize excessive shedding. Please contact your physician for individual recommendations on how to safely discontinue the use of Minoxidil.
Can I use this serum if I have sensitive skin or a sensitive scalp?
Absolutely! OS-01 HAIR was formulated to be safe for sensitive skin and scalps.
Is this serum suitable for all hair types?
Definitely! OS-01 HAIR is suitable for all hair types, including oily hair, and integrates easily into any hair care routine with visible results within as little as 90 days.
Is this safe for use during pregnancy or breastfeeding?
All OneSkin products are free of sulfates, parabens, and phthalates. Additionally, we post the full ingredient list of each product on the description pages. We recommend consulting with your doctor if you have any concerns about starting new products while pregnant or breastfeeding, as they know your particular needs best! As always, we recommend pregnant and breastfeeding women consult their physician with any questions or concerns.
Do I apply this before washing my hair or can I leave it on?
OS-01 HAIR should be left on and not rinsed. Apply 1mL of OS-01 HAIR serum 1-2x daily (AM or PM) directly to your scalp and massage in with your fingertips. Leave on, and do not rinse. For enhanced absorption, use a dermaroller on a clean scalp before application.
All Ingredients
Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.
OS-01 HAIR
- NWNicole W.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 4 out of 5 stars1 hour agoHealthy Scalp
I honestly don’t know if my hair is longer or thicker but I have seen a huge improvement in my scalp health. I didn’t even realize how dry and itchy my scalp was until this serum made it go away! No redness!
OneSkin3 minutes agoHi Nicole! Thank you so much for your wonderful 4-star feedback about our OS-01 HAIR SCALP SERUM! We're absolutely thrilled to hear that you're loving it - that kind of enthusiastic response really means the world to all of us at OneSkin!
It's fantastic that you've experienced such a meaningful improvement in your scalp health! The fact that the dryness and itchiness have gone away, and that you're noticing no redness is exactly the kind of tangible difference we hope our science-backed approach delivers. It's amazing how much better your scalp feels when it's actually getting the care it needs!
We're so grateful that you chose OS-01 HAIR SCALP SERUM for your routine, and we really appreciate you taking the time to share your experience. Your 4-star review truly means so much to us!
- DSDeborah S.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars3 days agoLove the title. Says exactly what it is.
Enjoying the product. After using my scalp no longer feels tight and itchy
- TETaylor E.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars2 weeks agoExcited to see results
I’ve only been using for a couple weeks but the serum is easy to apply and massages in well. I don’t think I’ve seen results yet, but this product is giving me hope after I noticed postpartum hair loss. At the very least I feel like I’m nourishing my hair and scalp.
- MLMargarette L.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars2 weeks agoDermaroller and Scalp Serum are a perfect combination
I have been using one Skin scalp serum with the DermaRoller for 3 weeks and already noticed a difference. I also enjoy the soothing massage.
- MWMe W.Verified ReviewerReviewingOS-01 HAIR SCALP SERUMI do not recommend this productRated 1 out of 5 stars3 weeks agoWhat about the unsafe ingredients
What about phenoxyethanol? Why would a banned ingredient be banned in other countries but not the USA? Please clarify this or I’m sending it back
OneSkin3 weeks agoHi!
We love that you're paying close attention to what's in your skincare! Ingredient and formulation transparency is incredibly important to us, so let's walk through this together.
First, some good news: phenoxyethanol is not banned in the United States, the European Union, or Japan. What differs between regions is how each one regulates it, not whether it's considered safe. In the EU and Japan, phenoxyethanol is legally capped at concentrations of 1% or less in cosmetic products. In the U.S., the FDA has reviewed phenoxyethanol and considers it safe for cosmetic use at that same general range, relying on an ongoing expert safety review process rather than a fixed legal percentage. So while the regulatory approach differs by country, the safety conclusion lines up everywhere: this ingredient is considered safe at low concentrations.
We also wanted to note that phenoxyethanol is not an ingredient in the formula for OS-01 HAIR!
For our other products, phenoxyethanol wasn't a default choice for us — it was a deliberate one, backed by our own testing. We included phenoxyethanol to ensure the stability of our formula, at a concentration significantly below the 1% safety cutoff recognized internationally. We chose it specifically because we ran extensive safety testing to confirm it would be gentle enough for sensitive skin while effectively preventing microbial growth within the formula — which matters just as much for your safety as the ingredients we leave out. OS-01 FACE is already formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum, phthalates, and PFAs, and phenoxyethanol was selected as one of the most thoroughly studied, well-tolerated preservative options available today, used at a concentration well within the range experts consider safe.
We know how much thought goes into choosing what you put on your skin, and we're genuinely glad you asked rather than just wondering. Our goal is for you to feel fully confident — not just comfortable, but excited — about every ingredient in your routine.
Related Articles
Citations
1 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.
2 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
3 Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259
4 Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318
5 Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269
6 Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/
7 Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic
8Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext
9 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
10 Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/
11 Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/
12 Shown in a 3 month beta test (brand led consumer perception study) with 22 participants and daily application of OS-01 HAIR (no dermaroller).