OS-01 HAIR
BENEFITS
Daily serum designed to nourish the scalp and reactivate your hair’s natural growth cycle01
Prevent a root cause of hair thinning
Prevents the accumulation of the cells that contribute to a disrupted hair growth cycle due to age, stress, and genetics.03-09
Scalp health
Safe for sensitive skin and promotes a healthy scalp microbiome, which can help foster healthy follicle function and hair density.01,09
Thicker, denser, fuller hair
Key ingredients complement the OS-01 peptide to promote strong, healthy hair.01
CLINICAL DATA
Visible results, scientifically validated
86.67
of participants showed an increase in hair density (average +39.62%) after 6 months 01
83.33
participants showed an increase in hair thickness (average +42.58%) after 6 months 01
80
of participants observed overall improvements in their hair after 3 months 01
76.67
of participants said the overall health of their hair improved after 6 months 01
5-STAR REVIEWS
See why customers love OS-01 HAIR
"Just fantastic regrowth in areas where I desperately needed it." — LaDonna L., Beta Tester
"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester
"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester
The proof is in the pictures
What makes OS-01 HAIR unique?
- Model
- Proprietary ingredient
- No harsh side effects
- Lightweight & non-greasy
- Drug-free
- No prescription
- Supports scalp health
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OS-01 HAIR
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Prescription Hair Treatments
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Leading Supplement
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- N/A
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Leading Hair Serum
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Invasive Treatments (PRP, hair transplant, etc.)
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DIY Oils
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The science behind OS-01 HAIR
Emerging research shows that senescence in hair follicles is linked to age-related thinning, stress-induced thinning, and pattern balding. 03-08
New research also shows that reducing senescent cells in hair follicles can stimulate regeneration.10,11 That's how our OS-01 peptide, proven to decrease cellular senescence in both hair and skin models, targets hair loss and thinning at its source.02,09
To test OS-01 HAIR’s ability to address senescence, our scientists treated senescence-induced cells with OS-01 HAIR. The results showed significantly reduced senescence levels, making OS-01 HAIR a promising candidate for addressing a key biological process linked to hair thinning and loss.03-09
6 active ingredients complement the OS-01 peptide
Getting started with OS-01 HAIR
Follow these easy steps for optimal results
- Apply 1 mL of serum (approximately 2 full droppers) directly to your scalp and massage in with fingertips
- Leave on, do not rinse
- Use up to 2 times daily
Your OS-01 HAIR questions answered
All Ingredients
Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.
OS-01 HAIR
- JJacquelynReviewingOS-01 HAIRI recommend this productRated 5 out of 5 stars3 minutes ago5 Stars
My hair feels healthier and stronger. Thicker also. Feels great
- LLLeigh L.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 starsYesterdayHuge difference already!!
I’ve only had this for a week but I feel like it’s already making a difference. And my hair seems fuller and my scalp less itchy.
OneSkinYesterdayThank you so much for your incredible feedback, Leigh! We are absolutely thrilled to hear that you're already noticing such amazing results with OS-01 HAIR after just one week - your enthusiasm is truly wonderful to read!
It's so rewarding to know that you're experiencing that fuller hair feeling and relief from scalp itchiness so quickly. Those early signs are exactly what we love to hear about, and it sounds like your scalp is responding beautifully to the serum!
We're honored that you decided to give our hair scalp serum a try, and we're so excited for you to continue experiencing these positive changes as you keep using it. Consistency is key and most users see consistent benefits and changes around the 3-6 month mark.
Thank you for taking the time to share such enthusiastic feedback with us - your experience truly means the world to us and we are always here to support you if you need anything!
- TTheresaVerified BuyerReviewingOS-01 HAIR SCALP SERUMRated 3 out of 5 stars2 days agoNot sure
I was really hopefully about this product for improving my hair, I’ve been using for at least a month now and while I can’t see a difference yet, I do appreciate that it needs time.. But I definitely have noticed it does have a residue which is very noticeable making my hair greasier than usual this makes it difficult to fit into schedule because I don’t want my hair to look like this all of the time while I’m going about my day with work and such so that’s a huge negative.
I’ll keep trying and hope for the best but I did want to share I do believe the “non residue/non greasy” claims are definitely not true for me.
OneSkinYesterdayHi Theresa!
Thank you so much for taking the time to share your experience with OS-01 HAIR and for your patience as you continue using it! We really appreciate your honest feedback about your first month of use.
We completely understand your frustration with the residue and greasiness you've been experiencing - that's definitely not the experience we want for our customers, especially when you're trying to fit the product into your daily routine with work and other commitments. We're so sorry to hear that the "non-greasy" claims haven't held true for your experience, and we totally get how disappointing that must be when you were hoping for something that would work seamlessly with your lifestyle.
Sometimes application technique and hair type can affect how the serum absorbs and feels on different people. A few tips that might help reduce the greasy feeling:
Try using a smaller amount - sometimes less product can absorb better than more
Apply to completely dry hair and scalp for better absorption
Focus the application mainly on your scalp rather than the hair strands themselves
Consider applying it at night before bed so it has time to absorb overnightWe really appreciate you giving OS-01 HAIR a try and for sharing your honest experience about both the timeline and the texture issues you've encountered. Your feedback helps us understand how our products work for different people and hair types, and we're grateful that you're willing to continue trying while sharing these important observations with us!
Hair growth follows a complex cycle—anagen (growth), catagen (transition), telogen (rest), and sometimes kenogen (lag)—and it takes time for follicles to regenerate and produce new strands.
In our 6-month clinical study with men and women experiencing hair thinning, participants using OS-01 HAIR (plus derma rolling) saw significant improvements:
+39.62% increase in hair count per cm² after 6 months (86.67% of participants)
+9.97% improvement in follicle spacing after 3 months (70% of participants)You can read more on the science here:
👉 Study Results
👉 Hair Growth & SenescenceConsistency is key so you may need some addition time to see results! We always recommend using OS-01 HAIR for at least 3 months to see if you start noticing changes.
Please reach out to us anytime if you need help or have questions. We are always here to support you!
- AHAlex H.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI do not recommend this productRated 2 out of 5 stars2 days agoVery unclear if it's helping.
It's been a few weeks; not much change; Hope it's not making things worse.
OneSkinYesterdayHi Alex!
Thank you for taking the time to share your feedback with us, and we understand your concern about not seeing much change after a few weeks of using OS-01 HAIR.
We know it can be frustrating when you're hoping to see results and aren't sure if the product is working for you yet. Hair and scalp health can take time to show visible improvements, and everyone's experience can vary based on individual factors.
Your feedback about the timeline and your concerns are really valuable to us as we work to help customers set appropriate expectations and have the best possible experience with our products.
A support team member will be reaching out to you shortly to discuss your experience further and provide some guidance on what to expect moving forward!
Thank you again for giving us the opportunity to address your concerns and for sharing your honest experience with us.
- SFSarah F.Verified BuyerReviewingOS-01 HAIRI recommend this productRated 5 out of 5 stars3 days agoResearch in progress
Only a few weeks in but immediate feed back is that this product feels weightless and doesn’t make hair look greasy
Related Articles
Citations
01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.
02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03 Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259
04 Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318
05 Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269
06 Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/
07 Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic
08Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext
09 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
10 Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/
11 Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/
12 Shown in a 3 month beta test (brand led consumer perception study) with 22 participants and daily application of OS-01 HAIR (no dermaroller).