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OS-01 BODY

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“By preventing senescent cells from releasing pro-aging factors, we can prevent healthy cells from becoming “zombies”–containing the spread of senescence and slowing down skin aging.” 3Science2

Alessandra Zonari, PhD
OneSkin Co-Founder & CSO 3Science2
OneSkin

OS-01 Peptide 3Science2

Our OS-01 formula targets aging at the cellular level, leaving skin nourished and resilient to daily stress 3Science2

Science Driven Innovation 3Science2

Utilizing advanced research to create effective skincare solutions. 3Science2

Inclusivity and Accessibility

Catering to a diverse range of skin types and needs.

Longevity and Sustainability

Focusing on long-term skin health and eco-friendly practices.

the 30-day one skin challenge

Instantly hydrated,deeply nourished skin 3Science2

93% agree their skin feels protected

87% agree skin looks visibly firmer

80% agree their skin appears to regenerate overnight

OUR APPROACH

Results that go beyond the lab 3Science2

7
Years of Research 3Science2

900
Peptides Screened

0
Patents & Publications

9000
Patents & Publications

OneSkin

Behind One Skin Longevity 3Science2

3Science2 As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning.

  1. Possible Increase of Skin’s Epidermal Thickness
  2. Increase of Key Biomarkers Associated with Cell Proliferation and Collagen Production
  3. May promote cell proliferation and collagen production, which can promote firmer, more renewed skin.
  4. Retinol Increases a Key Marker Associated with Skin Aging. OS-01 FACE Does Not.

How to apply OS-01 FACE and add to your routine 3Science2

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  • Dispense 1-2 pumps of OS-01 FACE onto fingers
  • Gently massage into skin on the face, neck, and hands
  • Use 2 times daily

3Science2

How it works 3Science2

Powered by the OS-01 Senescence Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03 3Science2

Frequently asked questions 3Science2

OS-01 BODY

4.7
Rated 4.7 out of 5 stars
Based on 3,474 reviews
Total 5 star reviews: 2.7k Total 4 star reviews: 446 Total 3 star reviews: 178 Total 2 star reviews: 56 Total 1 star reviews: 49
92%would recommend these products
3,474 reviews
  • MG
    M G. W.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    18 hours ago
    Body lotion

    This lotion absorbs quickly. It isn’t greasy nor full of perfumes. I hope it comes as a refill soon.

  • DB
    Debra B.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 4 out of 5 stars
    19 hours ago
    Velvety Smooth

    Have not had it long enough to see if it works on loose skin, but the velvety finish lasts all day and night.

    OneSkin
    4 minutes ago

    Hi Debra! Thank you so much for your wonderful 4-star feedback about OS-01 BODY MOISTURIZER! We're absolutely thrilled to hear that you're loving that incredible velvety finish and experiencing such long-lasting smoothness that carries you through both day and night - that kind of luxurious texture experience really means the world to all of us at OneSkin!

    We love that you're already experiencing such amazing results with the velvety feel and all-day comfort! Your observation about that beautiful smooth finish lasting from morning until night really shows how our carefully crafted body formula is delivering that perfect combination of rich moisture and elegant texture. It's so wonderful that you're getting that silky, pampered feeling that makes every application feel like a treat.

    Your honest perspective about being in the early stages of your OneSkin journey while already appreciating the incredible texture really helps us understand how our body moisturizer is fitting into your routine! We completely understand that the most dramatic visible improvements develop over time with consistent use, and the fact that you're already loving that velvety smoothness shows that your skin is getting exactly the kind of nourishing foundation it needs for long-term benefits.

    How exciting that you're experiencing such luxurious all-day comfort while building that consistent routine with OS-01 BODY! The fact that the velvety finish feels so amazing and lasts so beautifully really demonstrates how our science-backed formulation is working to support your skin's natural renewal process with every single application.

    Stories like yours about loving that incredible velvety texture and long-lasting smoothness are exactly why we're so passionate about what we do! Your satisfaction with how beautiful and comfortable your skin feels throughout the day really shows the wonderful foundation you're building for your skincare journey.

    Thank you for taking the time to share such encouraging feedback about your OS-01 BODY MOISTURIZER experience - your 4-star review truly means so much to us!

  • CG
    Cathy G.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    Best skin care product I’ve found.

    At 72 years old, I’ve tried a lot of skin lotions and skin care products. I have dry skin and sun damaged skin. Most lotions alleviate dry skin for a few hours. This product alleviates my dry skin until I shower again- at least 24 hours. It does this without making me feel sticky or greasy. Really quite remarkable. My only complaint is that it is terribly expressive so I use it much more sparingly than I would like. A body skin cream costing around $100 a bottle is out of reach for most people.

    OneSkin
    22 hours ago

    Hi Cathy! Thank you so much for your incredible 4-star feedback about OS-01 BODY MOISTURIZER! We're absolutely thrilled to hear that after 72 years and trying so many different products, you've found something that truly works for your dry and sun-damaged skin - that kind of life-changing experience really means the world to all of us at OneSkin!

    We love that you're experiencing such remarkable 24-hour hydration without any of that sticky or greasy feeling! Your observation about most lotions only working for a few hours while OS-01 BODY keeps your skin moisturized until your next shower really shows how our science-backed OS-01 Peptide is working at the cellular level to support your skin's natural ability to retain moisture and repair itself. It's so wonderful that you're getting that long-lasting comfort and protection in such a pleasant, non-greasy formula.

    Your honest perspective about wanting to use more but being mindful of the cost really helps us understand how important it is that every application delivers maximum benefit! We completely understand that investment is a significant consideration, and we're so grateful that you're finding such remarkable results even when using it more sparingly. The fact that you're still experiencing those incredible 24-hour benefits shows just how effectively our carefully crafted formulation is working to transform your skin health.

    How wonderful that at 72, you've discovered a product that outperforms everything else you've tried for your specific skin concerns! Your experience with the exceptional moisturizing power and comfortable feel really demonstrates how our peptide technology is designed to address the unique needs of mature and sun-damaged skin with results that last.

    Stories like yours about finding truly remarkable relief for dry, sun-damaged skin after decades of searching are exactly why we're so passionate about what we do! Your satisfaction with the long-lasting hydration and non-greasy feel really shows the incredible difference you're making in your daily comfort and skin health.

    Thank you for taking the time to share such encouraging and honest feedback about your OS-01 BODY MOISTURIZER experience - your 4-star review truly means so much to us!

  • JB
    Jessica B.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    The most effective lotion I’ve tried yet

    I am a huge fan of this lotion! It completely got rid of my KP bumps on my arms, and has made my skin so much smoother.

  • KM
    Kendall M.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    Loving so far...

    New user of One Skin and loving so far! Goes on smooth and skin stays very hydrated, even in the AZ summer heat!

    OneSkin
    22 hours ago

    Hi Kendall! Thank you so much for your wonderful 4-star feedback about OS-01 BODY! We're absolutely thrilled to hear that you're loving your experience as a new OneSkin user and that you're finding the smooth application and incredible hydration so perfect, even in that intense Arizona summer heat - that kind of positive experience with our body formula really means the world to all of us at OneSkin!

    We love that you're experiencing such amazing hydration benefits with OS-01 BODY, especially in those challenging desert conditions! Your observation about how smoothly it goes on while keeping your skin so well-hydrated even during the AZ summer really shows how our carefully crafted formula is working to support your skin's moisture barrier when you need it most. It's so wonderful that you're getting that combination of easy application and lasting hydration protection all in one product.

    Your enthusiasm about the smooth application and incredible staying power against that intense summer heat really shows how OS-01 BODY is fitting perfectly into your daily routine! We designed this formula specifically to deliver deep, lasting moisture while feeling comfortable on your skin, and it sounds like you're experiencing exactly the kind of effortless hydration and protection we hoped for, even in such demanding weather conditions.

    How exciting that you're starting your OneSkin journey with such positive results and finding OS-01 BODY so effective against the Arizona heat! The fact that your skin is staying so beautifully hydrated despite those intense summer temperatures really demonstrates how our science-backed formulation is working to support your skin's natural resilience and moisture retention.

    Stories like yours about loving the smooth application and amazing hydration benefits even in challenging climates are exactly why we're so passionate about what we do! Your satisfaction as a new user really shows the wonderful foundation you're building for long-term skin health and comfort.

    Thank you for taking the time to share such encouraging feedback about your OS-01 BODY experience - your 4-star review truly means so much to us!

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
02 Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05 https://academic.oup.com/bbb/article/72/12/3211/5941013 06 https://pubmed.ncbi.nlm.nih.gov/32522955/ 07 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886

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