OS-01 EYE CREAM
Hydrate and firm ultra-delicate skin with our daily eye cream, formulated with the highest concentration of the OS-01 Peptide™.01
- Improves texture, tone, and elasticity
- Increase collagen by an average of +130% in lab studies
- Dermatologist tested, fragrance-free, safe for sensitive skin
- Exclusive early access to new products
- Earn 2x points on all recurring orders
- Easily change, skip or cancel anytime
LIMITED TIME OFFER
Travel-size OS-01 BODY with your first subscription
✭ You’re earning 92 points with OneSkin Loyalty Program ✭
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Try it risk-free for 30 days!
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BENEFITS
Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 03
Wrinkle reduction
Boosts collagen to visibly smooth lines and wrinkles.01
Firmness
Supports skin health for a firmer, more lifted appearance.01
Hydration
Strengthens the skin barrier to lock in moisture and keep skin hydrated.01
5-star reviews
See why customers love OS-01 EYE
“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.
"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.
"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.
"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
96
of participants reported improved texture and tone 01
91
of participants reported improved radiance 01
88
of participants showed improved hydration 01
86
of participants had improved elasticity 01
3 active ingredients complement the OS-01 peptide
Getting started with OS-01 EYE
Follow these easy steps for optimal results
- Dispense 1 pump onto tip of finger
- Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.05,06
All Ingredients
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
02 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
03 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
06 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
OS-01 EYE CREAM
- NKNatalie K.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 4 out of 5 stars2 hours agoVery expensive for the amount you get but I like that it’s clean
It’s nearly impossible to find clean facial and body products so I’m glad to have something to use. I think it’s working but I don’t know if I see a huge difference yet.
OneSkin7 minutes agoHi Natalie!
Thank you so much for taking the time to share your honest feedback about the OS-01 EYE CREAM! — we really appreciate the 4 stars and are so glad you're finding value in having clean skincare options!
We completely understand your point about the price relative to the amount, and we know that investing in premium skincare is a real consideration. The concentrated nature of OS-01 EYE means a little goes a long way — typically just a small amount is needed for both eyes, so while the tube is compact, most customers find it lasts longer than they initially expect when used as directed.
We're thrilled to hear that you appreciate having clean products to use! We know how challenging it can be to find effective formulations that are also free from the ingredients you want to avoid, and that's exactly why we've worked so hard to create products that deliver results without compromise.
As for seeing results, we totally understand that eye area improvements can be subtle and take time to become noticeable. Most customers start seeing visible changes around the 4-6 week mark with consistent daily use, and the benefits continue to build over time as the OS-01 peptide works at the cellular level to target senescent cells around the delicate eye area.
Thank you for choosing OneSkin and for being so thoughtful in your review, Natalie — feedback like yours helps other customers know what to expect, and we're grateful you're giving our clean formulations a try!
- TKTamara K.Verified BuyerReviewingOS-01 EYE CREAMI recommend this productRated 5 out of 5 stars3 hours agoDelightful!
Am pleased to report this cream not only helps noticeably with wrinkles and fine lines, but I’m wearing less concealer now too. Customer service from this company has been five star too. Bravo!
- HSHolly S.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 stars22 hours agoBest eye cream ever!
This is my absolute favorite eye cream ever! It goes on so smoothly and absorbs quickly. The skin around my eyes is soft and supple!!! One bottle has lasted me 5 months so far (I usually only apply it once a day). I already ordered and received my 2nd bottle so I'm ready to refill when this one runs out!
- SCSandra C.Verified BuyerReviewingOS-01 EYE CREAMI recommend this productRated 5 out of 5 starsYesterdayFavorite
I have tried many eye creams. This is my favorite. It feels good going on and I really feel like it is helping the sking around my eyes be more healthy.
- KFKathleen F. C.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 starsYesterdayOne skin
My skin feels good after using for only 2 months. Visibly it’s difficult to a difference yet. I just got my first refill so time will tell.
OneSkin3 minutes agoHi Kathleen!
Thank you so much for taking the time to share your experience with the OS-01 EYE CREAM and for the wonderful 5-star rating! We're thrilled to hear that your skin is already feeling good after just 2 months of use — that's such a positive sign that the OS-01 peptide is working at the cellular level.
We completely understand that visible changes around the eye area can take time to become noticeable, and you're absolutely right that time will tell! Most customers start seeing more visible improvements around the 4-6 week mark, and the benefits continue to build with consistent use as the formula works to target senescent cells in that delicate area. Since you're already feeling a difference in how your skin feels, you're likely well on your way to seeing those visual results too.
We're so glad you're staying consistent with your first refill — that ongoing commitment to your routine is really what makes the difference with cellular-level skincare. The fact that your skin feels good is already telling us that OS-01 EYE is working its magic, and we're excited for you to continue experiencing those benefits as you move forward.
Thank you for choosing OneSkin and for being so thoughtful about giving the process time to work, Kathleen — we appreciate your patience and trust in our products!
