If your lips feel constantly chapped, seem to be losing volume faster than the rest of your face, and need endless reapplication of balm, there’s actually a biological reason for it. Lip skin is ultra-vulnerable to aging factors, and most products just cover up the problem.
That's why we’re excited to introduce OS-01 LIP Mask, our latest innovation powered by our patented longevity science! After validating OS-01’s ability to reverse markers of skin aging, we wanted to apply that same science to our most vulnerable skin, the lips, and ask the obvious question: Could the same biology-first approach solve the everyday cycle of chapping, shrinking volume, and the constant need for reapplication?[1]
Why Focus on Lip Skin?
Lip tissue has limited natural oils and a thinner outer layer, so it loses moisture easily and shows lines sooner. Cumulative UV and daily stressors like pollution, which can easily damage that weaker barrier, create the perfect conditions for heightened premature skin aging and cellular senescence.[2]
With age, lips lose collagen, elastin, and hyaluronic acid. This leads to greater dehydration and a decline in volume, definition, and virbancy.[3,4] What's more, these changes can have significant impacts on overall facial appearance. In fact, lip volume is the strongest perceived attribute of facial aging.[5]
That is why your average lip balm won't cut it when it comes to addressing the signs of lip aging, and where OS-01 LIP Mask comes in.
Introducing OS-01 LIP Mask: A Ritual That Works While You Sleep
Your skin’s repair mechanisms don't take the night off. In fact, skin repair peaks during deep sleep as your circadian rhythm shifts into regenerative mode. This triggers increased DNA repair, collagen production, skin barrier recovery, and skin penetrability, making nighttime an optimal window for targeted interventions.[6]
OS-01 LIP Mask was intentionally formulated to align with this peak repair phase. While you sleep, the OS-01 Peptide™ works below the surface, supporting collagen and elastin production, promoting hyaluronic acid synthesis, and reducing markers of cellular aging—the result: lips that feel hydrated instantly and look smoother, fuller, and healthier over time.[7]
Lab Data
OS-01 LIP Mask was born in the OneSkin lab and underwent significant testing on ex vivo skin samples to determine efficacy. These results confirmed that OS-01 LIP Mask could significantly improve key biomarkers associated with hyaluronic acid, elastin, and collagen production. [1]
Because OS-01 LIP Mask targets the root causes of lip aging, it's a game-changer for maintaining lip health and combating gradual volume loss or the constant struggle of chapped, dry lips.
Consumer Perception Data
While every product starts in the lab to verify the safety and efficacy of our products on a cellular level, our products are designed for real life use. To verify that the cellular benefits observed in our lab would translate to effects observed in real life, we relied on our beta testers who used the product over 12 weeks and reported their experience. Luckily, OS-01 LIP Mask not only met but exceeded our expectations for improving lip hydration, volume, and wrinkles.[1]
Here's what those beta testers had to say about OS-01 LIP Mask:
“I love this product so much already. My lips already look better! And I love the way the product feels, love the packaging, etc.”
-Lauren A.
“One of the best overnight lip masks I’ve used. The product stays on and is not sticky. My lips feel great in the morning.”
-Astrid D
“This is a total game-changer! It keeps my lips so hydrated all day long, and I've noticed they look way more plump and youthful since I started using it. It's long-lasting, and the biggest win is that my fine lines are less noticeable, and the flaking is completely gone! I'm genuinely impressed!”
-Abbie W.
And the data backs it up, out of our testers:
- 98% agreed lips felt instantly hydrated and moisturized upon application
- 98% would recommend OS-01 LIP to friends and family
- 95%+ agreed lips felt smoother, softer, and deeply moisturized after 4 weeks
- 84% reported reduced fine lines and wrinkles on their lips after 8 weeks
- 81% reported improved fullness after 8 weeks
- 81% reported reduced fine lines and wrinkles around the lip border after 4 weeks
Conclusion
OS-01 LIP Mask represents a new standard in lip care—one rooted in longevity science, not surface-level fixes. Whether you’re looking to restore hydration, smooth fine lines, or support your skin’s long-term health, this nightly treatment makes it easy to wake up with lips that look and feel their best.
Key Takeaways
- Lip skin has a weaker barrier and fewer natural defenses, making it more vulnerable to dehydration and visible aging.
- OS-01 LIP Mask redefines lip care with a biology-first approach that helps restore your most fragile skin.
- By targeting cellular aging pathways and promoting collagen, elastin, and hyaluronic acid production, OS-01 LIP Mask restores healthier-looking lips over time.
References
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8251770/
- https://journals.lww.com/plasreconsurg/abstract/2019/02000/aging_of_the_upper_lip__part_i__a_retrospective.17.aspx
- https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.16317
- https://link.springer.com/rwe/10.1007/978-3-642-27814-3_91-2
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6777699/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7496161/
