OS-01 EYE CREAM
Hydrate and firm ultra-delicate skin with our daily eye cream, formulated with the highest concentration of the OS-01 Peptide™.01
- Improves texture, tone, and elasticity
- Increase collagen by an average of +130% in lab studies
- Dermatologist tested, fragrance-free, safe for sensitive skin
- Exclusive early access to new products
- Earn 2x points on all recurring orders
- Easily change, skip or cancel anytime
LIMITED TIME OFFER
Travel-size OS-01 BODY with your first subscription
✭ You’re earning 92 points with OneSkin Loyalty Program ✭
Free shipping on orders over
Try it risk-free for 30 days!
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BENEFITS
Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 03
Wrinkle reduction
Boosts collagen to visibly smooth lines and wrinkles.01
Firmness
Supports skin health for a firmer, more lifted appearance.01
Hydration
Strengthens the skin barrier to lock in moisture and keep skin hydrated.01
5-star reviews
See why customers love OS-01 EYE
“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.
"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.
"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.
"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
96
of participants reported improved texture and tone 01
91
of participants reported improved radiance 01
88
of participants showed improved hydration 01
86
of participants had improved elasticity 01
3 active ingredients complement the OS-01 peptide
Getting started with OS-01 EYE
Follow these easy steps for optimal results
- Dispense 1 pump onto tip of finger
- Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.05,06
All Ingredients
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
02 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
03 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
06 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
OS-01 EYE CREAM
- KNKerri N.Verified BuyerReviewingOS-01 EYE CREAMI recommend this productRated 4 out of 5 stars29 minutes agoNice
This eye cream is nice. Very hydrating. Haven’t seen any reduced wrinkles but I’m on my first bottle.
OneSkin4 minutes agoHi Kerri! Thank you so much for your wonderful 4-star feedback about OS-01 EYE CREAM! We're absolutely thrilled to hear that you're finding it so hydrating and nice to use - that kind of positive experience with the formulation really means the world to all of us at OneSkin!
We love that you're experiencing such great hydration benefits with your OS-01 EYE CREAM routine! Your observation about how hydrating it feels really shows how our science-backed OS-01 Peptide is working to support the delicate skin around your eyes. It's so wonderful that you're enjoying the daily application experience and finding the formula so pleasant to use as part of your skincare routine.
Your realistic perspective about timing with your first bottle really shows such a thoughtful approach to skincare! We completely understand that the most meaningful visible improvements often develop with continued use over time, and many of our customers find that changes around the eye area become more noticeable as they continue their routine. The fact that you're already experiencing such wonderful hydration is such a great foundation for that ongoing journey.
How exciting that you're finding OS-01 EYE CREAM so nice and hydrating while maintaining those realistic expectations about visible changes! The fact that you're enjoying the formula and how it feels really demonstrates that you're giving the delicate eye area exactly the kind of gentle, science-backed support it needs to thrive.
Stories like yours about loving the hydrating benefits while taking a patient approach to visible results are exactly why we're so passionate about what we do! Your satisfaction with how nice the eye cream feels while being realistic about the timeline really shows the thoughtful way you're approaching your eye care routine.
Thank you for taking the time to share such encouraging feedback about your OS-01 EYE CREAM experience - your 4-star review truly means so much to us!
- NKNatalie K.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 4 out of 5 starsYesterdayVery expensive for the amount you get but I like that it’s clean
It’s nearly impossible to find clean facial and body products so I’m glad to have something to use. I think it’s working but I don’t know if I see a huge difference yet.
OneSkinYesterdayHi Natalie!
Thank you so much for taking the time to share your honest feedback about the OS-01 EYE CREAM! — we really appreciate the 4 stars and are so glad you're finding value in having clean skincare options!
We completely understand your point about the price relative to the amount, and we know that investing in premium skincare is a real consideration. The concentrated nature of OS-01 EYE means a little goes a long way — typically just a small amount is needed for both eyes, so while the tube is compact, most customers find it lasts longer than they initially expect when used as directed.
We're thrilled to hear that you appreciate having clean products to use! We know how challenging it can be to find effective formulations that are also free from the ingredients you want to avoid, and that's exactly why we've worked so hard to create products that deliver results without compromise.
As for seeing results, we totally understand that eye area improvements can be subtle and take time to become noticeable. Most customers start seeing visible changes around the 4-6 week mark with consistent daily use, and the benefits continue to build over time as the OS-01 peptide works at the cellular level to target senescent cells around the delicate eye area.
Thank you for choosing OneSkin and for being so thoughtful in your review, Natalie — feedback like yours helps other customers know what to expect, and we're grateful you're giving our clean formulations a try!
- TKTamara K.Verified BuyerReviewingOS-01 EYE CREAMI recommend this productRated 5 out of 5 starsYesterdayDelightful!
Am pleased to report this cream not only helps noticeably with wrinkles and fine lines, but I’m wearing less concealer now too. Customer service from this company has been five star too. Bravo!
- HSHolly S.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 stars2 days agoBest eye cream ever!
This is my absolute favorite eye cream ever! It goes on so smoothly and absorbs quickly. The skin around my eyes is soft and supple!!! One bottle has lasted me 5 months so far (I usually only apply it once a day). I already ordered and received my 2nd bottle so I'm ready to refill when this one runs out!
- SCSandra C.Verified BuyerReviewingOS-01 EYE CREAMI recommend this productRated 5 out of 5 stars2 days agoFavorite
I have tried many eye creams. This is my favorite. It feels good going on and I really feel like it is helping the sking around my eyes be more healthy.
