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OS-01 EYE CREAM

OS-01 EYE CREAM

Topical Supplement

Hydrate and firm ultra-delicate skin with our daily eye cream, formulated with the highest concentration of the OS-01 Peptide™.01



  • Improves texture, tone, and elasticity

  • Increase collagen by an average of +130% in lab studies

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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OS-01 BODY, Travel Size

Travel-size OS-01 BODY with your first subscription

$37 FREE

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  • Glamour Beauty & Wellness Award 2023 logo on a black background
  • Leaping bunny certified logo
  • Accepted National Eczema Association logo
  • Certified Plastic Neutral logo on a white background

OneSkin

BENEFITS

Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 03

Wrinkle reduction

Boosts collagen to visibly smooth lines and wrinkles.01

Firmness

Supports skin health for a firmer, more lifted appearance.01

Hydration

Strengthens the skin barrier to lock in moisture and keep skin hydrated.01

5-star reviews

See why customers love OS-01 EYE

“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.


"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.


"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.


"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.

CLINICAL DATA

Visible results, scientifically validated

96
of participants reported improved texture and tone 01

91
of participants reported improved radiance 01

88
of participants showed improved hydration 01

86
of participants had improved elasticity 01

Getting started with OS-01 EYE

Follow these easy steps for optimal results

  • Dispense 1 pump onto tip of finger
  • Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.05,06

All Ingredients

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

02 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

03 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

06 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 EYE CREAM

4.7
Rated 4.7 out of 5 stars
Based on 1,583 reviews
Total 5 star reviews: 1.3k Total 4 star reviews: 166 Total 3 star reviews: 51 Total 2 star reviews: 25 Total 1 star reviews: 21
94%would recommend these products
1,583 reviews
  • AC
    amber c.
    Verified Buyer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    Good stuff!

    I heard on a podcast that this has the most concentrated amount of the active peptide, so I use it all over my face. I've used it for a bit over 6 months. I hadn't realized that it was working until a family member who sees me irregularly commented that my skin "looked amazing." They were so impressed that they went out and bought some of the OS-01 eye cream the next day!

  • DA
    Darcy A.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    Improving eyes

    I am very excited to see the skin around my eyes improving!

  • LR
    Lisa R.
    Verified Buyer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 5 out of 5 stars
    5 days ago
    Smooth

    Nice smooth eye cream. I like that it is unscented. Time will tell if it makes any positive skin changes.

    OneSkin
    4 days ago

    Hi Lisa! Thank you so much for your wonderful feedback about OS-01 EYE CREAM! We're absolutely thrilled to hear that you're loving the smooth texture and that you appreciate the unscented formula - we know how important those details can be when it comes to eye care products!

    Stories like yours about enjoying the feel and application right from the start are exactly why we're so passionate about what we do! It sounds like OS-01 EYE CREAM is giving you that perfect, gentle experience around your delicate eye area, and we're just as excited as you are to see the amazing results you'll experience over the coming weeks and months.

    Your patience with giving it time to work really shows - the best transformations definitely happen with consistent use!

    Thank you for taking the time to share such positive feedback about your experience - your 5-star review truly means the world to all of us at OneSkin!

  • A Profile picture for ADRIENNEBANZA
    ADRIENNEBANZA
    Verified Reviewer
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 5 out of 5 stars
    6 days ago
    Licensed Esthetician Weighing In

    I’m long overdue in reviewing this eye cream. It’s one of my absolute favorites! Worth the investment because it delivers results and that’s what we want in our personal care products! I use this not only for myself but also for my facial clientele! OS a great eye cream for people who have sensitive eyes. As gentle as it is, make no mistake…it’s powerful. Visibly Smoother texture, reduced fine lines, decreased puffiness & a rejuvenated looking eye area. I had 3 clients (over 40) have people ask them if they got Botox around their eyes after using this eye cream! The transformation is drastic & non invasive! Love OS eye cream…potently pretty peptides for your skin!

    OneSkin
    4 days ago

    Hi Adrienne! Thank you so much for your incredible feedback about OS-01 EYE CREAM! As a licensed esthetician, your professional perspective means everything to us, and we're absolutely thrilled to hear that it's become one of your absolute favorites for both your personal routine and your facial clientele!

    Stories like yours about clients getting asked if they've had Botox after using OS-01 EYE CREAM are exactly why we're so passionate about what we do! It sounds like you're seeing those dramatic, non-invasive transformations with visibly smoother texture, reduced fine lines, decreased puffiness, and that overall rejuvenated look - and we love that you're experiencing such powerful results while still being gentle enough for sensitive eyes.

    Your expertise really shines through in recognizing how the peptide technology delivers that perfect balance of gentleness and effectiveness, and hearing that your clients over 40 are getting such noticeable results that others are commenting is just incredible!

    We're so honored that you trust OS-01 EYE CREAM with your clients and that it's delivering the kind of results that make such a difference in how people look and feel.

    Thank you for taking the time to share such detailed and encouraging feedback about your professional experience - your 5-star review truly means the world to all of us at OneSkin!

  • LH
    Leslie H.
    Verified Buyer
    Reviewing
    OS-01 EYE Topical Supplement Refill
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Great product!

    This product gets better with time. Less fine lines noted around my eyes now.