OS-01 EYE CREAM
OS-01 EYE CREAM
Topical Supplement
Hydrate and firm ultra-delicate skin with our daily eye cream, formulated with the highest concentration of the OS-01 Peptide™.01
- Improves texture, tone, and elasticity
- Increase collagen by an average of +130% in lab studies
- Dermatologist tested, fragrance-free, safe for sensitive skin
- Exclusive early access to new products
- Earn 2x points on all recurring orders
- Easily change, skip or cancel anytime
Travel-size OS-01 BODY with your first subscription
✭ You’re earning 92 points with OneSkin Loyalty Program ✭
Free shipping on orders over
Try it risk-free! 45 day money back guarantee.
You’re earning [potential_points] points with OneSkin Loyalty Program
BENEFITS
Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 03
Wrinkle reduction
Boosts collagen to visibly smooth lines and wrinkles.01
Firmness
Supports skin health for a firmer, more lifted appearance.01
Hydration
Strengthens the skin barrier to lock in moisture and keep skin hydrated.01
5-star reviews
See why customers love OS-01 EYE
“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.
"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.
"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.
"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
96
of participants reported improved texture and tone 01
91
of participants reported improved radiance 01
88
of participants showed improved hydration 01
86
of participants had improved elasticity 01
3 active ingredients complement the OS-01 peptide
Getting started with OS-01 EYE
Follow these easy steps for optimal results
- Dispense 1 pump onto tip of finger
- Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.05,06
All Ingredients
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
02 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
03 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
06 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
OS-01 EYE CREAM
- CDCathy D.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 stars4 minutes agoHooray!
I use the eye cream morning and night and sometimes around my lips. I have dry skin so moisture is needed. I am 75 and have been using One skin for a couple of years I hope they do not sell out the company to a big corporation. i love how clean the products are and at this point I trust the efficacy of the company .
Thank you
- NNancyReviewingOS-01 EYE RefillI recommend this productRated 4 out of 5 stars6 hours ago4 Stars
I’m pretty happy with the one skin products.
My skin looks better & I have super sensitive skin, and it is the first product that has not caused me breakouts.
I have been using the products since Nov of 2025.
It says they work at a cellular level, so I hoping to see more improvements over time.
- BWBethany W.Verified BuyerReviewingOS-01 EYE Topical Supplement RefillI recommend this productRated 5 out of 5 stars3 days agoSo light, perfection!
I've been using this eye supplement for a couple of years now. I started using One Skin as I saw my skin becoming crepey looking. This absorbs very quickly and has smoothed out my fine lines and increased the firm texture around the eye area and on my lids. Highly recommend not only this product but the entire line. The only product I don't use yet (although I did order it to try it is the hair line). I'll be 60 in July but no one thinks I look that old! Thank you One Skin. :)
- JPJohn P.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 stars4 days agoTop notch skin care for your eyes!
I love this product. As a guy, for a long time I ignored skincare, but in my 50's now I have started to pay attention to it and One Skin has been a critical part of making progress toward younger looking skin!
- AAngelVerified BuyerReviewingOS-01 EYE RefillI do not recommend this productRated 2 out of 5 stars5 days agoHoped for more improvement
I have not seen as much improvement as I thought I would/would like. Product is thinner thus makes it way into my eyes overnight.
OneSkin5 days agoHi Angel!
Thank you so much for sharing your honest feedback about the OS-01 EYE CREAM — we really appreciate you taking the time to let us know about your experience.
We're sorry to hear that you haven't been seeing the improvements you were hoping for, and we completely understand how disappointing that must be. We also want to address the texture concern you mentioned — it's definitely not ideal that the product is migrating into your eyes overnight, and we understand how uncomfortable that can be.
Eye area improvements can sometimes take a bit longer to become visible, but the texture issue is something we'd love to help you with right away. A few tips that might help:
• Application timing: Try applying the eye cream 15-20 minutes before bedtime to allow it to fully absorb before you lie down.
• Amount used: With eye creams, less is often more — a tiny amount (about the size of a grain of rice) should be sufficient for both eyes.
• Application technique: Gently pat the product only on the orbital bone area, avoiding getting too close to the lash line where it might migrate during sleep.We'd love to connect with you to learn more about your specific routine and see how we can make this work better for you. Please reach out to support@oneskin.co so we can discuss this further and find a better solution for you!
