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OS-01 EYE CREAM

OS-01 EYE CREAM

Topical Supplement

Hydrate and firm ultra-delicate skin with our daily eye cream, formulated with the highest concentration of the OS-01 Peptide™.01



  • Improves texture, tone, and elasticity

  • Increase collagen by an average of +130% in lab studies

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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OS-01 BODY, Travel Size

Travel-size OS-01 BODY with your first subscription

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  • Glamour Beauty & Wellness Award 2023 logo on a black background
  • Leaping bunny certified logo
  • Accepted National Eczema Association logo
  • Certified Plastic Neutral logo on a white background

OneSkin

BENEFITS

Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 03

Wrinkle reduction

Boosts collagen to visibly smooth lines and wrinkles.01

Firmness

Supports skin health for a firmer, more lifted appearance.01

Hydration

Strengthens the skin barrier to lock in moisture and keep skin hydrated.01

5-star reviews

See why customers love OS-01 EYE

“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.


"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.


"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.


"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.

CLINICAL DATA

Visible results, scientifically validated

96
of participants reported improved texture and tone 01

91
of participants reported improved radiance 01

88
of participants showed improved hydration 01

86
of participants had improved elasticity 01

Getting started with OS-01 EYE

Follow these easy steps for optimal results

  • Dispense 1 pump onto tip of finger
  • Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.05,06

All Ingredients

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

02 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

03 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

06 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 EYE CREAM

4.7
Rated 4.7 out of 5 stars
Based on 1,618 reviews
Total 5 star reviews: 1.3k Total 4 star reviews: 171 Total 3 star reviews: 52 Total 2 star reviews: 26 Total 1 star reviews: 21
94%would recommend these products
1,618 reviews
  • A
    Alma
    Reviewing
    OS-01 EYE CREAM
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    5 Stars

    Soft and smooth and hopefully effective

  • EE
    Emme E.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Eye Topical Supplement

    Incredible improvement with tone, laxity and reduced lines.

  • CC
    Catherine C.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Perfect for aging eyes

    I’ve noticed a softening of those little lines at the outside of my eyes as well as a bit more plumpness on the eyelids. So far, your products have come through.

  • CM
    Charlotte M.
    Verified Buyer
    Reviewing
    OS-01 EYE Topical Supplement Refill
    I recommend this product
    Rated 4 out of 5 stars
    Yesterday
    Recycling

    I love the recycling

    OneSkin
    5 hours ago

    Hi Charlotte! Thank you so much for your wonderful 4-star feedback about OS-01 EYE CREAM! We're absolutely thrilled to hear that you love the recycling aspect - that enthusiasm for our sustainable packaging approach is exactly what gets us so excited about making skincare choices that are good for both your skin and the planet!

    We love that you're appreciating how the refill system lets you continue your eye care routine while making an environmentally conscious choice! Your decision to choose the refill option really shows how you can maintain the amazing benefits of our OS-01 Peptide while reducing waste and supporting sustainability. It's so wonderful that you've found a way to care for your delicate eye area while also caring for the environment.

    The fact that you're loving the recycling aspect of OS-01 EYE speaks volumes about how our refill program is delivering on both effective skincare and environmental responsibility! Your experience of appreciating that sustainable approach really shows how we can make choices that feel good on multiple levels - great for your skin health and great for your values.

    Stories like yours about loving the recycling benefits while continuing your skincare routine are exactly why we're so passionate about offering these sustainable options! Your enthusiasm for the environmental aspect really shows the confidence you have in making choices that align with both your skin goals and your commitment to reducing waste.

    Thank you for taking the time to share such encouraging feedback about your experience - your 4-star review truly means the world to all of us at OneSkin!

  • MM
    Michele M.
    Verified Buyer
    Reviewing
    OS-01 EYE Refill
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Better skin around eyes

    As a physician who studies anti-aging medicine, I came across this company 5 years ago. I now use so many of their products. I understand how it works and can see the difference! Highly recommend.