OS-01 HAIR SCALP SERUM
OS-01 HAIR SCALP SERUM
Topical Supplement
- Nourishes the scalp, and promotes visibly thicker, fuller, denser hair01
- 81% showed a +40% improvement in visible hair density after 6 months01
- Dermatologist tested, fragrance-free, suitable for sensitive skin
1 month supply delivered every 1 month.
3 month supply delivered every 3 months.
6 month supply delivered every 6 months.
Free OneSkin Travel bag + EYE travel size + 2 dermarollers
- Plastic neutral refillable packaging
- Exclusive early access to new products
- Earn 2x points for free products on all recurring orders
- Easily change, skip or cancel anytime
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BENEFITS
Daily scalp serum designed to nourish the scalp and support visibly healthier and younger-looking hair.
Promote hair longevity
Addresses visible hair changes associated with age and stress.
Hair health starts at the scalp
Suitable for sensitive skin and supports a healthy scalp microbiome to support healthy hair.
Support thicker, denser, fuller-looking hair
Key ingredients complement the OS-01 Peptide to promote strong, healthy-looking hair for progressive improvements in visible density and thickness.
CLINICAL DATA
Visible results, scientifically validated
81
of participants showed an increase in visible hair density (average +40%) after 6 months 01
78
of participants showed an increase in hair visible thickness (average +43%) after 6 months01
81
of participants observed overall improvements in their hair after 3 months 01
78
of participants said the overall health of their hair improved after 6 months 01
5-STAR REVIEWS
See why customers love OS-01 HAIR
"Just fantastic growth in areas where I desperately needed it." — LaDonna L., Beta Tester
"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester
"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester
The proof is in the pictures
What makes OS-01 HAIR unique?
- Model
- Proprietary ingredient
- No harsh side effects
- Lightweight & non-greasy
- Drug-free
- No prescription
- Supports scalp health
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OS-01 HAIR
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Prescription Hair Treatments
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Leading Supplement
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- N/A
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Leading Hair Serum
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Invasive Treatments (PRP, hair transplant, etc.)
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DIY Oils
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6 active ingredients complement the OS-01 peptide
How to Apply OS-01 HAIR
- We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
- Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose. Apply the serum directly to your scalp, starting at your natural part or hairline.
- Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
- Massage the serum into your scalp with your fingertips to ensure even distribution.
- Do not rinse. Style as usual.
- Use daily on dry or damp hair.
A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.
Your OS-01 HAIR questions answered
All Ingredients
Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.
OS-01 HAIR SCALP SERUM
- NWNick W.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars3 hours agoHair Serum
Packaging is really nice. Still waiting to see if it works. only been a couple of weeks
- MWMargaret W.Verified BuyerReviewingOS-01 HAIRI recommend this productRated 4 out of 5 stars2 days agoHair tonic
Just started using this product and have not noticed any difference in my hair, hopping to see a difference in a few weeks.
OneSkin8 hours agoHi Margaret!
Thank you so much for taking the time to share your initial experience with OS-01 HAIR and for giving it a try! We completely understand that you haven't noticed any changes yet — and honestly, that's totally normal and expected at this early stage. Your optimism about seeing results in the coming weeks is exactly the right mindset.
Here's what's happening behind the scenes: OS-01 HAIR works at the cellular level to target senescent cells in hair follicles that accumulate over time and disrupt the natural hair growth cycle. Because it's addressing the root cause of hair thinning and loss, the improvements build gradually as your follicles reactivate and your scalp environment becomes healthier and more supportive of dense hair growth.
In our clinical study, participants began seeing visible improvements around the 90-day mark, with significant results continuing to build over time. By 6 months, 81% of participants showed an average improvement of +40% in visible hair density. So while it requires patience, the science shows that consistent daily use really does lead to meaningful, lasting changes.
For the best results, make sure you're applying 1mL directly to your scalp 1-2 times daily and massaging it in with your fingertips — no need to rinse. Consistency is absolutely key with OS-01 HAIR.
We're genuinely excited for you to experience what's possible with continued use, Margaret. Thank you for trusting OneSkin with your hair goals, and please don't hesitate to reach out to us at support@oneskin.co if you have any questions along the way!
- KWKristin W.Verified BuyerReviewingOS-01 HAIRI recommend this productRated 4 out of 5 stars2 days agoToo soon to tell
1 1/2 bottles in. Possible new growth, but early to tell.
OneSkin8 hours agoHi Kristin!
Thank you so much for taking the time to share your honest experience with OS-01 HAIR SCALP SERUM — we genuinely appreciate your patience and commitment to giving it a real try. It sounds like you're being thoughtfully observant about any changes, and we completely understand that at 1.5 bottles in, you may still be waiting to see more definitive results.
The good news is that what you're noticing could very well be the beginning of real progress. Here's the science behind why it takes time: hair follicles accumulate senescent — or "zombie" — cells over time that disrupt the natural hair growth cycle, leading to thinning and loss. OS-01 HAIR is specifically designed to target that cellular senescence at the root, reactivating the hair growth cycle and improving the scalp environment that supports healthy, dense hair. Because this works at the cellular level, visible changes build gradually rather than appearing overnight.
Our clinical study found that participants showed significant improvements in hair density at both 3 and 6 months — with results continuing to improve over time. By 6 months, 81% of participants showed an average improvement of +40% in visible hair density. The product page also notes that visible results can appear within as little as 90 days with consistent use — so if you're around that mark, you may be right at the threshold where things start to become more noticeable.
A couple of things that can help maximize your results:
• Consistency is key: Apply 1mL directly to the scalp 1-2x daily and massage in with your fingertips. Do not rinse.
• Add the dermaroller: Using a dermaroller on a clean scalp before application has been shown to enhance absorption and can meaningfully support results.We're truly rooting for you, Kristin — and we're here if you have any questions or want to talk through your routine. Please don't hesitate to reach out to us at support@oneskin.co!
- CFCamilla F.Verified BuyerReviewingOS-01 HAIRI recommend this productRated 5 out of 5 stars1 week agoSo grateful
At age 50, I began to have significant thinning at my temples. I haven’t wanted to go the monoxonil route because of side effects, so I’ve tried so many alternative products with okay results. Since I have used peptides for my eyelashes for years, when I came across this peptide hair serum I decided to experiment despite it being pricey. After only a few months of use, at age 56, I finally have nice thick regrowth at my temple areas. So grateful.
- PRPatrick R.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars1 week agoawesome
Great product. Recommend greatly.
Related Articles
Citations
01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.
02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
More Scientific Resources
Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259
Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318
Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269
Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/
Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic
Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext
Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/
Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/