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OS-01 HAIR SCALP SERUM

4.4
4.4 out of 5
4.4 (231)

OS-01 HAIR SCALP SERUM

Topical Supplement

4.4
4.4 out of 5
4.4 (231)
The first daily scalp serum powered by the OS-01 PeptideTM to help support fuller, thicker-looking hair with age and stress.



  • Nourishes the scalp, and promotes visibly thicker, fuller, denser hair01

  • 81% showed a +40% improvement in visible hair density after 6 months01

  • Dermatologist tested, fragrance-free, suitable for sensitive skin


Disclaimer: Dermaroller is for cosmetic use only. Not intended to diagnose, treat, cure, or prevent any disease.
SAVE 10% EVERY ORDER
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1 month supply delivered every 1 month.

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3 month supply delivered every 3 months.

SAVE 25% EVERY ORDER
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6 month supply delivered every 6 months.

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BENEFITS

Daily scalp serum designed to nourish the scalp and support visibly healthier and younger-looking hair.

Promote hair longevity

Addresses visible hair changes associated with age and stress.

Hair health starts at the scalp

Suitable for sensitive skin and supports a healthy scalp microbiome to support healthy hair.

Support thicker, denser, fuller-looking hair

Key ingredients complement the OS-01 Peptide to promote strong, healthy-looking hair for progressive improvements in visible density and thickness.

CLINICAL DATA

Visible results, scientifically validated

81
of participants showed an increase in visible hair density (average +40%) after 6 months 01

78
of participants showed an increase in hair visible thickness (average +43%) after 6 months01

81
 of participants observed overall improvements in their hair after 3 months 01

78
of participants said the overall health of their hair improved after 6 months 01

5-STAR REVIEWS

See why customers love OS-01 HAIR

"Just fantastic growth in areas where I desperately needed it." — LaDonna L., Beta Tester

"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester

"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester

What makes OS-01 HAIR unique?

  • Proprietary ingredient
  • No harsh side effects
  • Lightweight & non-greasy
  • Drug-free
  • No prescription
  • Supports scalp health
    • OS-01 HAIR

    • Prescription Hair Treatments

    • X
    • X
    • X
    • X
    • X
    • Leading Supplement

    • X
    • N/A
    • X
    • Leading Hair Serum

    • X
    • Invasive Treatments (PRP, hair transplant, etc.)

    • X
    • X
    • N/A
    • N/A
    • DIY Oils

    • X
    • X

How to Apply OS-01 HAIR

  1. We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
  2. Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose.  Apply the serum directly to your scalp, starting at your natural part or hairline.
  3. Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
  4. Massage the serum into your scalp with your fingertips to ensure even distribution.
  5. Do not rinse. Style as usual.
  6. Use daily on dry or damp hair.

A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.

Your OS-01 HAIR questions answered

HOW IT WORKS

Powered by the OS-01 Senescence Blocking Peptide™

Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin, scalp, and hair aging, for skin and hair that looks and feels younger and healthier over time.02

All Ingredients

Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.

OS-01 HAIR SCALP SERUM

4.4
Rated 4.4 out of 5 stars
Based on 231 reviews
Total 5 star reviews: 154 Total 4 star reviews: 42 Total 3 star reviews: 22 Total 2 star reviews: 6 Total 1 star reviews: 7
85%would recommend these products
231 reviews
  • K
    Kelli
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    5 Stars

    I really like the hair product... It makes my hair feel refreshed and it even helps when I Wake up with bad hair day. It makes my scalp feel invigorated. It forces me to give myself a little head massage, which I know is good for my brain health.

  • RN
    Rebecca N.
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    Regrew my hair after chemo!

    This product was very important in the process to regrow some of the hair I lost after chemo ..amazing product!

  • DM
    Deana M.
    Verified Buyer
    Reviewing
    OS-01 HAIR
    I recommend this product
    Rated 4 out of 5 stars
    3 days ago
    Great for Eyebrows

    I've been using this for almost a year. I use it on my hair, but where I found it has really made a difference is with my eyebrows. They were very thin from low thyroid function. I got that resolved, but my outer eyebrows were almost non-existent. Within a month I could tell a difference, and now three months later, they are almost completely grown in and a nice, dark color!

    OneSkin
    8 hours ago

    Hi Deana! Thank you so much for your wonderful 4-star feedback about OS-01 HAIR! We're absolutely thrilled to hear that you've been using it for almost a year and that you've discovered such amazing benefits for your eyebrows - that kind of creative application and incredible results really means the world to all of us at OneSkin!

    We love that you found OS-01 HAIR to be so effective for addressing the thinning eyebrows from your thyroid function challenges! Your experience with seeing a difference within just a month and then achieving almost complete regrowth with beautiful dark color after three months really shows how our science-backed OS-01 Peptide is working to support healthy hair growth in ways that go beyond what you might initially expect. It's so wonderful that you're getting that dual benefit of using it on your hair while also discovering this fantastic solution for your eyebrow concerns.

    Your story about the transformation from almost non-existent outer eyebrows to full, nicely colored brows really shows such an inspiring journey with OS-01 HAIR! We completely understand how challenging it can be when thyroid issues affect hair growth, and the fact that you're seeing such remarkable improvement in both thickness and color demonstrates how effectively our carefully crafted formula is supporting your hair follicles' natural renewal process.

    How exciting that you've been able to address both your hair and eyebrow needs with one product while building such consistent results over the past year! Your dedication to using OS-01 HAIR regularly and your patience in allowing the peptide technology to work really shows the wonderful foundation you've built for long-term hair health.

    Stories like yours about discovering unexpected benefits and achieving such dramatic eyebrow transformation are exactly why we're so passionate about what we do! Your persistence with the product and excitement about the amazing regrowth results really demonstrates the confidence you've developed in the OS-01 HAIR experience.

    Thank you for taking the time to share such encouraging and detailed feedback about your OS-01 HAIR journey - your 4-star review truly means so much to us!

  • NW
    Nick W.
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Hair Serum

    Packaging is really nice. Still waiting to see if it works. only been a couple of weeks

  • MW
    Margaret W.
    Verified Buyer
    Reviewing
    OS-01 HAIR
    I recommend this product
    Rated 4 out of 5 stars
    1 week ago
    Hair tonic

    Just started using this product and have not noticed any difference in my hair, hopping to see a difference in a few weeks.

    OneSkin
    1 week ago

    Hi Margaret!

    Thank you so much for taking the time to share your initial experience with OS-01 HAIR and for giving it a try! We completely understand that you haven't noticed any changes yet — and honestly, that's totally normal and expected at this early stage. Your optimism about seeing results in the coming weeks is exactly the right mindset.

    Here's what's happening behind the scenes: OS-01 HAIR works at the cellular level to target senescent cells in hair follicles that accumulate over time and disrupt the natural hair growth cycle. Because it's addressing the root cause of hair thinning and loss, the improvements build gradually as your follicles reactivate and your scalp environment becomes healthier and more supportive of dense hair growth.

    In our clinical study, participants began seeing visible improvements around the 90-day mark, with significant results continuing to build over time. By 6 months, 81% of participants showed an average improvement of +40% in visible hair density. So while it requires patience, the science shows that consistent daily use really does lead to meaningful, lasting changes.

    For the best results, make sure you're applying 1mL directly to your scalp 1-2 times daily and massaging it in with your fingertips — no need to rinse. Consistency is absolutely key with OS-01 HAIR.

    We're genuinely excited for you to experience what's possible with continued use, Margaret. Thank you for trusting OneSkin with your hair goals, and please don't hesitate to reach out to us at support@oneskin.co if you have any questions along the way!

Citations

01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.

02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

More Scientific Resources

Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259

Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318

Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269 

Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/

Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic 

Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext 

Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/ 

Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/