OS-01 HAIR SCALP SERUM
- Nourishes the scalp, and promotes visibly thicker, fuller, denser hair01
- 81% showed a +40% improvement in visible hair density after 6 months01
- Dermatologist tested, fragrance-free, suitable for sensitive skin
1 month supply delivered every 1 month.
3 month supply delivered every 3 months.
6 month supply delivered every 6 months.
- Plastic neutral refillable packaging
- Exclusive early access to new products
- Earn 2x points for free products on all recurring orders
- Easily change, skip or cancel anytime
✭ You’re earning 62 points with OneSkin Loyalty Program ✭
Free shipping on orders over
Try it risk-free for 30 days!
You’re earning [potential_points] points with OneSkin Loyalty Program
BENEFITS
Daily scalp serum designed to nourish the scalp and support visibly healthier and younger-looking hair.
Promote hair longevity
Addresses visible hair changes associated with age and stress.
Hair health starts at the scalp
Suitable for sensitive skin and supports a healthy scalp microbiome to support healthy hair.
Support thicker, denser, fuller-looking hair
Key ingredients complement the OS-01 Peptide to promote strong, healthy-looking hair for progressive improvements in visible density and thickness.
CLINICAL DATA
Visible results, scientifically validated
81
of participants showed an increase in visible hair density (average +40%) after 6 months 01
78
of participants showed an increase in hair visible thickness (average +43%) after 6 months01
81
of participants observed overall improvements in their hair after 3 months 01
78
of participants said the overall health of their hair improved after 6 months 01
5-STAR REVIEWS
See why customers love OS-01 HAIR
"Just fantastic growth in areas where I desperately needed it." — LaDonna L., Beta Tester
"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester
"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester
The proof is in the pictures
What makes OS-01 HAIR unique?
- Model
- Proprietary ingredient
- No harsh side effects
- Lightweight & non-greasy
- Drug-free
- No prescription
- Supports scalp health
-
OS-01 HAIR
-
✓
-
✓
-
✓
-
✓
-
✓
-
✓
-
-
Prescription Hair Treatments
- ✓
- X
- X
- X
- X
- X
-
-
Leading Supplement
- X
- ✓
- N/A
- ✓
- ✓
- X
-
-
Leading Hair Serum
- X
- ✓
- ✓
- ✓
- ✓
- ✓
-
-
Invasive Treatments (PRP, hair transplant, etc.)
- X
- X
- N/A
- ✓
- ✓
- N/A
-
-
DIY Oils
- X
- ✓
- X
- ✓
- ✓
- ✓
-
6 active ingredients complement the OS-01 peptide
How to Apply OS-01 HAIR
- We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
- Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose. Apply the serum directly to your scalp, starting at your natural part or hairline.
- Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
- Massage the serum into your scalp with your fingertips to ensure even distribution.
- Do not rinse. Style as usual.
- Use daily on dry or damp hair.
A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.
Your OS-01 HAIR questions answered
All Ingredients
Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.
OS-01 HAIR SCALP SERUM
- MHMasey H.Verified BuyerReviewingOS-01 HAIRI recommend this productRated 5 out of 5 stars2 days agoEasy Application and Great Results
This product os easy to use without any sort of residue. With consistent use the results are visible. My hairdresser consistently remarks on my new growth each visit.
- SKSheila K.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars5 days agoHair serum
I have been using it for 2 weeks so far. My hair feels healthier and softer. Too soon to understand if new hair growth. Easy to apply and does not ruin your styled hair.
- DCDebbie C. P.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 4 out of 5 stars6 days agoWorks good
This has helped some but not as much as I thought. I was of course hoping for results like the pictures on the website. I have been using most days for 3 months. I plan to keep using for the 12 weeks and then decide whether I will continue.
OneSkin11 minutes agoHi Debbie!
Thank you so much for taking the time to share your experience with the OS-01 HAIR SCALP SERUM and for the thoughtful 4-star review! We're glad to hear that you're seeing some positive changes after 3 months of consistent use — that's exactly what we like to see as the OS-01 peptide works at the cellular level to support scalp health.
We completely understand that you were hoping to see more dramatic results like those featured on our website, and we know it can feel a bit discouraging when progress feels more gradual than expected. Hair and scalp improvements can be subtle at first and often build over time, which is why we recommend that full 12-week commitment you're planning to complete.
You're absolutely doing the right thing by sticking with your routine through the 12-week mark! 3 months is when, on average, customers start seeing results! Consistency is key here! Since you're already seeing some benefits at the 3-month point, you're likely building toward even better results.
We really appreciate your honesty about the timeline and your realistic expectations — feedback like yours helps other customers understand what the journey looks like and sets appropriate expectations for their own experience.
Thank you for choosing OneSkin and for being so dedicated to giving the full process time to work, Debbie — we're hopeful that those next few weeks will bring you even more of the results you're looking for!
- OSOlivia S.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI do not recommend this productRated 1 out of 5 stars6 days agodoesnt work
after trying consistently for months, i did not notice a difference in terms of growth, density, or breakage. definitely should not believed the hype about this product from any "influencer." everyone's hair/scalp is so different so you just do what works for you.
because oneskin products are marketed so heavily on certain tag/google search words, i wouldn't trust their other products either to help with "cellular" aging.
OneSkin4 minutes agoHi Olivia!
Thank you so much for taking the time to share your honest feedback about OS-01 HAIR SCALP SERUM — we genuinely appreciate you letting us know about your experience after using it consistently for months, and we're truly sorry to hear that you didn't see the improvements you were hoping for in growth, density, or breakage.
We completely understand how disappointing and frustrating it must be to commit to a hair routine for months without noticing the changes you were looking for. That's absolutely not the experience we want for anyone, and your concerns are completely valid.
You're absolutely right that everyone's hair and scalp is so different, and what works for some people doesn't always work for others. Hair growth and health can be influenced by so many factors — genetics, hormones, stress, diet, and underlying scalp conditions.
We completely respect your skepticism about influencer recommendations and understand your concerns about marketing in the hair care space. Your experience is your own, and we appreciate you sharing it honestly so other customers can make informed decisions based on real experiences like yours.
Regarding your concerns about our other products and cellular aging claims — we understand your hesitation, and we want you to feel confident in any products you choose to try. Your feedback about marketing and expectations is really valuable for us to hear.
We'd love to connect with you personally to better understand your experience and see if there's anything we can do to help. Please feel free to reach out to support@oneskin.co if you'd like to discuss this further.
Thank you for choosing OneSkin and for sharing this important feedback with us, Olivia!
- CWCharles W.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars1 week agoI like it
I like it.. non greasy, low odor. Too early to tell if it works, but I’m hopeful.
Related Articles
Citations
01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.
02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
More Scientific Resources
Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259
Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318
Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269
Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/
Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic
Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext
Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/
Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/