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OS-01 BODY MOISTURIZER

250 mL / 8.45 fl oz

OS-01 BODY MOISTURIZER

Topical Supplement

250 mL / 8.45 fl oz

Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 PeptideTM and OneSkin Longevity ScienceTM.01



  • Improves skin texture, appearance, and hydration

  • Strengthens the skin barrier by up to +41%

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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Skincare bottle labeled 'ONE SKIN' on a beige background

LIMITED TIME OFFER

Travel-size OS-01 FACE with your first subscription

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  • Certified Plastic Neutral logo on a white background
  • Leaping bunny certified logo
  • Accepted National Eczema Association logo

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BENEFITS

Nourishing body moisturizer and targeted treatment for thin, crepey skin

Smooth texture

Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01

Deep hydration

Replenishes and locks in hydration to keep skin soft, plump, and nourished.01

Barrier support

Fortifies the skin barrier to protect against daily stressors and moisture loss.01

5-STAR REVIEWS

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

CLINICAL DATA

Visible results, scientifically validated

93
of participants reported improved hydration 01

70
of participants reported improved appearance 01

70
of participants reported improved texture 01

41
Improvement in skin barrier function was measured 01

Getting started with OS-01 BODY

Follow these easy steps for optimal results

  • Apply to arms, legs, chest, back, and stomach
  • Massage until absorbed
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

All Ingredients

Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide

Citations

01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 BODY MOISTURIZER

4.7
Rated 4.7 out of 5 stars
Based on 3,422 reviews
Total 5 star reviews: 2.7k Total 4 star reviews: 440 Total 3 star reviews: 176 Total 2 star reviews: 54 Total 1 star reviews: 47
92%would recommend these products
3,422 reviews
  • ML
    Melissa L.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Moisturizer

    Soothing to skin, I have many allergies and this lotion does not irritate my skin.

  • MP
    Marti P.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    21 minutes ago
    Moisturizer

    Very hydrating… feels like liquid velvet. 😍

  • BK
    Barbara K.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    Rated 3 out of 5 stars
    3 hours ago
    One Skin Body Lotion

    I have been using this twice a day for a few weeks and its nice, but not great. I wouldn't say it lives up to the social media posts, although definitely not offensive or harmful - just "so-so."

    OneSkin
    3 hours ago

    Hi Barbara,

    Thank you for taking the time to share your honest experience with OS-01 BODY MOISTURIZER — we genuinely appreciate your candid feedback, and "so-so" definitely isn't the experience we're aiming to give you.

    We completely understand that feeling of wanting more from a product, especially when you're being consistent with twice-daily use. Body skin actually presents unique challenges compared to facial skin — it's often thicker, exposed to more environmental stressors, and can take longer to show visible changes. OS-01 BODY is formulated to work at the cellular level, targeting senescent cells that contribute to skin thinning, dryness, and loss of firmness over time. That kind of deep, foundational change often builds gradually, and many customers find that the improvements become more noticeable as they continue using it consistently.

    We know social media can sometimes set expectations that feel hard to match in real life. What we can share is that in our clinical studies, participants using OS-01 BODY showed measurable improvements in skin thickness, hydration, and barrier function — but those changes developed over weeks and months, not days.

    Your feedback about the product feeling "nice, but not great" is incredibly valuable to us. Sometimes small adjustments to application — like using it on slightly damp skin to boost absorption, or focusing on areas where you most want to see improvement — can help you get more from the formula.

    We'd love to help you optimize your routine to see if we can move that experience from "so-so" to something that feels genuinely worthwhile. Please feel free to reach out to our team at support@oneskin.co if you'd like personalized guidance.

    Thank you for sticking with OneSkin and for sharing such helpful, honest feedback with us!

  • MB
    Michelle B.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    5 hours ago
    Great Product

    I can see an improvement in my skin!

  • RM
    Rob M.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    18 hours ago
    Love It

    It has been a great product.