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OS-01 BODY MOISTURIZER

250 mL / 8.45 fl oz

OS-01 BODY MOISTURIZER

Topical Supplement

250 mL / 8.45 fl oz

Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 PeptideTM.01



  • Improves skin texture, appearance, and hydration

  • Strengthens the skin barrier by up to +41%

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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OS-01 FACE, Travel Size

Travel-size OS-01 FACE with your first subscription

$42 FREE

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  • Certified Plastic Neutral logo on a white background
  • Leaping bunny certified logo
  • Accepted National Eczema Association logo

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BENEFITS

Nourishing body moisturizer and targeted treatment for thin, crepey skin

Smooth texture

Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01

Deep hydration

Replenishes and locks in hydration to keep skin soft, plump, and nourished.01

Barrier support

Fortifies the skin barrier to protect against daily stressors and moisture loss.01

5-STAR REVIEWS

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

CLINICAL DATA

Visible results, scientifically validated

93
of participants reported improved hydration 01

72
of participants reported improved appearance 01

70
of participants reported improved texture 01

41
Improvement in skin barrier function was measured 01

Getting started with OS-01 BODY

Follow these easy steps for optimal results

  • Apply to arms, legs, chest, back, and stomach
  • Massage until absorbed
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

All Ingredients

Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide

Citations

01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 BODY MOISTURIZER

4.7
Rated 4.7 out of 5 stars
Based on 3,299 reviews
Total 5 star reviews: 2.6k Total 4 star reviews: 417 Total 3 star reviews: 166 Total 2 star reviews: 51 Total 1 star reviews: 46
92%would recommend these products
3,299 reviews
  • DF
    Debbi F.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    6 minutes ago
    Love this lotion!!

    This is by far my favorite body lotion! It really works leaving your skin very silky! Lightweight, not sticky. Just amazing!

  • NK
    Nancy K.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    4 hours ago
    The change in my 68 year old skin

    I recently purchased the one skin product line and I am thrilled. Having taken care of my face mostly, I do not have that many wrinkles. That being said, I have definitely neglected my body. Within 1 week I have noticed an amazing change in the skin of my arms. The wrinkled skin is definitely reduced!!! I am thrilled. I am also so happy to support the wonderful group of female scientist that created this line. I am hooked! Thank you sooo much!!!

  • AA
    Angela A.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I do not recommend this product
    Rated 2 out of 5 stars
    8 hours ago
    Not sure

    I have been using OS-01 Body for a few months now, every single day. I'm not sure I'm seeing much results. I still have crepey skin.

    OneSkin
    7 hours ago

    Hi Angela!

    Thank you so much for sharing your experience and for your dedication to using OS-01 BODY MOISTURIZER every single day — that consistency truly means a lot to us. We're sorry to hear you haven't been seeing the results you were hoping for with crepey skin.

    Crepey skin can be one of the more stubborn concerns to address, and results can vary depending on a few key factors. Here are some tips that may help maximize your results with OS-01 BODY MOISTURIZER:

    Application method: Apply OS-01 BODY MOISTURIZER to slightly damp skin immediately after showering, while your skin is still warm. This helps with absorption and can significantly boost efficacy.
    Amount used: Make sure you're using a generous amount — crepey or textured skin often benefits from a slightly more liberal application to ensure full coverage.
    Targeted massage: Spend an extra 30–60 seconds massaging OS-01 BODY MOISTURIZER into areas with crepey skin using upward, circular motions to encourage circulation and absorption.

    We'd love to help you get the most out of your routine. Please don't hesitate to reach out to our team directly at support@oneskin.co if you'd like more personalized guidance — we're here for you!

  • CS
    chad s.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    9 hours ago
    OS-01 Body Lotion

    This is hans down the best lotion I've used! It feels good immediately after applying to my body. I've subscribed to the produrct so that it arrive each month.

  • LV
    Lisa V. n.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    11 hours ago
    just wonderful

    I love the lightness of this moisturizer, and the way it seems to quench the thirst of my skin.