Active ingredients that complement the OS-01 peptide
Tremella Fuciformis Sporocarp Mushroom extract
This antioxidant-rich natural extract reduces UV-induced water and collagen loss induced by uv damage.
Ceramides
Supports skin’s natural lipid barrier to protect, boost moisture retention and repair dry and sensitive skin.
Sulforaphane
Found in Lepidium Sativum Sprout Extract, this antioxidant has potent antimicrobial and anti-inflammatory properties.
Saccharide isomerate
A prebiotic shown to support the healthy bacteria on skin.
Genistein
A powerful anti-inflammatory antioxidant that helps prevent and fade photoaging and dark spots.
How it works
Powered by the OS-01 Senescence Peptide™
The only peptide scientifically proven to reverse skin aging at the cellular level. 03,07
All Ingredients
OS-01 BODY: Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 PeptideTM
OS-01 LIP MASK: Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan. *OS-01 PeptideTM
Citations
01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1





