FACE, EYE + LIP TRIO
The complete longevity trio for your most exposed skin - face, eyes, and lips.
- Protect against 3 main drivers of lip skin aging with Bare Blush Lip Shield SPF 15+
- Boosts visible radiance, firmness, and barrier resilience with OS-01 FACE Moisturizer
- Strengthen delicate eye skin and boost visible elasticity with OS-01 EYE Cream
- Dermatologist tested, fragrance-free, suitable for sensitive skin
- Exclusive early access to new products
- Earn 2x points on all recurring orders
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OS-01 FACE MOISTURIZER
OS-01 EYE CREAM
Ingredients that complement the OS-01 PeptideTM
Hyaluronic acid
Supports hydration, plumpness, and elasticity in both facial skin and lips.
Vitamin E
A potent antioxidant that helps neutralize oxidative stress and supports daily repair from UV and environmental exposure.
Barrier-supporting lipids & oil
A tailored blend of biomimetic lipids and nourishing oils strengthens the skin barrier across facial skin, eye skin, and lips, helping improve comfort, softness, and long-term resilience.
How it works
Powered by the OS-01 Senescence Peptide™
Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.
FACE, EYE + LIP TRIO
- MNMargaret N.Verified BuyerReviewingOS-01 LIP SHIELD SPF 15+I recommend this productRated 5 out of 5 stars3 minutes agoLip Shield SPF
This product was a total surprise. After 2 weeks of daily use, 90% of my lifetime dry and peeling lip condition has disappeared! I expected protection but received healing as well (and I have tried every balm and botanical on the market).
This lip shield is moist, long lasting and transforming the fullness of my lips back to decades ago. I'm addicted... and racing to check out the tinted version!
Heart felt gratitude to the One Skin team.
- MWMorgan W.Verified BuyerReviewingOS-01 LIP SHIELD SPF 15+I recommend this productRated 5 out of 5 stars8 hours agoSo soothing
Smooth and soothing lip shield. Has a slight white cast.
- LMLeah M.Verified BuyerReviewingOS-01 LIP SHIELD SPF 15+I recommend this productRated 5 out of 5 stars10 hours agoGreat SPF
This is the best SPF lip balm I have had, it's hydrating, not sticky, adds a nice shine. Love it!
- JKJennifer K.Verified BuyerReviewingOS-01 LIP SHIELD SPF 15+I recommend this productRated 5 out of 5 stars10 hours agoGreat Lip Shield
Very hydrating !!
- CCCarolyn C.Verified BuyerReviewingOS-01 LIP SHIELD SPF 15+I recommend this productRated 5 out of 5 stars12 hours agoMy favorite lip gloss
I love this product. I'm not a big lipstick wearer, but I appreciate the light color and moisturizing qualities for my older lips. It's easy to apply and lasts quite a long time, plus I love the added spf!
Full ingredient list
OS-01 FACE ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
OS-01 EYE Ingredients
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
OS-01 LIP SHIELD SPF 15+ BARE BLUSH ingredients
Active ingredients: Zinc Oxide 5.5%
Inactive ingredients: Simmondsia Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae rhamnoides (Sea Buckthorn) Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Lactic Acid, Octyldodecanol, Sorbitan Oleate, Alumina, Magnesium Oxide, Palmitic Acid, Iron oxides (CI 77491, CI 77492, CI 77499), Titanium Dioxide (CI 77891), Red 33 Lake (CI 17200), Red 7 Lake (CI 15850).
Drug Facts
Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen
Uses
- Helps prevent sunburn
- If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.
Warnings
- For external use only.
- Do not use on damaged or broken skin.
- Stop use and ask a doctor if rash occurs.
- Keep out of reach of children.
Citations
01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
