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OS-01 FACE MOISTURIZER

50 mL / 1.7 fl oz

OS-01 FACE MOISTURIZER

Topical Supplement

50 mL / 1.7 fl oz

Smooth and firm skin with our daily moisturizer for the face and neck, powered by the OS-01 Peptide™.01



  • Boosts hydration, elasticity, and barrier function

  • 96% showed an improvement in firmness and radiance

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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OS-01 BODY, Travel Size

Travel-size OS-01 BODY with your first subscription

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  • Leaping bunny certified logo
  • Accepted National Eczema Association logo
  • Certified Plastic Neutral logo on a white background
  • Clinically Tested to Support the Skin Microbiome

OneSkin

Benefits

Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment

Hydration

Boosts barrier function, allowing your skin to retain moisture and stay hydrated.02

Firmness

Switches off the cells that degrade collagen, helping skin stay firm.01,03

Radiance

Enhances skin tone and texture, helping skin look and feel smooth and radiant.02

5-STAR REVIEWS

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

CLINICAL DATA

Visible results, scientifically validated

100
of participants had improved smoothness 02

96
of participants had improved firmness, radiance, and tone 02

90
of participants had improved elasticity 02

86
of participants had improved appearance of fine lines and wrinkles 02

Getting started with OS-01 FACE

Follow these easy steps for optimal results

  • Dispense 1-2 pumps onto fingers
  • Gently massage into skin on the face and neck
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

OS-01 FACE MOISTURIZER

4.7
Rated 4.7 out of 5 stars
Based on 6,286 reviews
Total 5 star reviews: 5.1k Total 4 star reviews: 798 Total 3 star reviews: 254 Total 2 star reviews: 73 Total 1 star reviews: 62
94%would recommend these products
6,286 reviews
  • SG
    Sierra G.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    Love this environmental refill option!

    To start, the product: I have been using One Skin eye and face for about 3 years. I am 48 years old. Most people think I'm in my late 30s to early 40s. The last time I went to get Botox (in my jaw for clenching as I don't get it for cosmetic purposes), the injector—who is a board-certified medical doctor—was training some other injectors. They all wanted to know what I do for my skin. I said I use One Skin, which the doctor had heard about but was hesitant to try because she wasn't convinced whether it would be effective. I told her that as soon as I started using One Skin, it was like it "stopped time" for my skin. I didn't look younger, but I didn't look older. After using it for 2 years, however, I could tell that it had indeed reversed the appearance of my skin's age. I had less wrinkles than I'd had in my late 30s! It is an investment and it takes time, but it is worth it. Now, as for a review of the pouch: I have used several different skincare refills for various brands in the past and One Skin's refill pouch is the best. First it is easy to pop in and out of the base. Second, you can use every single drop with this design because it literally sucks the product up through the pouch until the pouch is completely flat. But again, because this design is so great, I can cut open the pouch and capture any traces left before throwing away the pouch. I seriously cannot commend this design enough. EVERY skincare brand should be using this type of design.

  • LS
    Lorry S.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    6 hours ago
    Feel younger

    Since I started using this on my face I actually enjoy looking at the 66 y/o face looking back from mirror. Even my lips feel and look better making me want to try the one skin just for lips.

  • CC
    Catherine C.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    7 hours ago
    Skin feels so soft

    I love the feel of my skin since I’ve been using OS-01 Face. Definitely softer, smoother, with more plumpness. Thank you!

  • MM
    Michele M.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    16 hours ago
    Better, younger skin

    The science is real on os-1. I use it daily and have for 5 years. Worth it!

  • LC
    Lisa C.
    Verified Buyer
    Reviewing
    OS-01 FACE Topical Supplement Refill
    I recommend this product
    Rated 5 out of 5 stars
    17 hours ago
    One skin & my face.

    I am 68yrs old. Several years ago my daughter told me to get this product. She really liked it. I did finally & saw great results to my skin. Due to financial reasons I stopped purchasing for about a year. I'm back again & my skin looks & feels so much again. I am so glad to be back & so is my skin!!