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Free shipping on orders over $79.00 USD

OS-01 FACE MOISTURIZER

50 mL / 1.7 fl oz

OS-01 FACE MOISTURIZER

Topical Supplement

50 mL / 1.7 fl oz

Smooth and firm skin with our daily moisturizer for the face and neck, powered by the OS-01 Peptide™.01



  • Boosts hydration, elasticity, and barrier function

  • 96% showed an improvement in firmness and radiance

  • Dermatologist tested, fragrance-free, safe for sensitive skin

SAVE 15%
  • Exclusive early access to new products
  • Earn 2x points on all recurring orders
  • Easily change, skip or cancel anytime
OS-01 BODY, Travel Size

Travel-size OS-01 BODY with your first subscription

$37 FREE
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  • Leaping bunny certified logo
  • Accepted National Eczema Association logo
  • Certified Plastic Neutral logo on a white background
  • Clinically Tested to Support the Skin Microbiome

OneSkin

Benefits

Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment

Hydration

Boosts barrier function, allowing your skin to retain moisture and stay hydrated.02

Firmness

Switches off the cells that degrade collagen, helping skin stay firm.01,03

Radiance

Enhances skin tone and texture, helping skin look and feel smooth and radiant.02

5-STAR REVIEWS

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

CLINICAL DATA

Visible results, scientifically validated

100
of participants had improved smoothness 02

96
of participants had improved firmness, radiance, and tone 02

90
of participants had improved elasticity 02

86
of participants had improved appearance of fine lines and wrinkles 02

Getting started with OS-01 FACE

Follow these easy steps for optimal results

  • Dispense 1-2 pumps onto fingers
  • Gently massage into skin on the face and neck
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

OS-01 FACE MOISTURIZER

4.7
Rated 4.7 out of 5 stars
Based on 6,236 reviews
Total 5 star reviews: 5.1k Total 4 star reviews: 790 Total 3 star reviews: 254 Total 2 star reviews: 72 Total 1 star reviews: 62
94%would recommend these products
6,236 reviews
  • JL
    Jennifer L.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    Genius packaging

    This packaging is genius. This company has figured it out, and I don’t see why others don’t ditch their “Instagram” worthy flashy, wasteful packaging for something like this.

  • PP
    Paula P.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    1 hour ago
    Easy and Sustainable

    I love the ease of this pop in refill and the fact that it cuts down on the waste of big, bulky, plastic containers.

  • CB
    Connie B.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Skin Texture Improvement

    I've been using OS-01 Face for 8 months now and have experienced a notable improvement in the texture and fine lines on my face and around my eyes as a 60+ woman. Looking forward to seeing if longer use will continue to show improvement. I am hopeful!

  • TJ
    Tambra J.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    love the packaging

    Love that the pouch fits in the existing casing

  • RE
    Rebecca E.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    For life….

    Some of my closest friends have all just in the past week or so talked about my forehead. It was whacky the timing each had - all within a week! But then again, I’ve been consistent now with my OS-01 Face for a few months so it lines up! When I first started to use it, the feeling and texture of my skin were noticeably better. It took a few months, and now I look a lot healthier too! Consistency is key, but great product and will continue to buy for as long as I have skin! 🤣