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OS-01 FACE MOISTURIZER

50 mL / 1.7 fl oz

OS-01 FACE MOISTURIZER

Topical Supplement

50 mL / 1.7 fl oz

Smooth and firm skin with our daily moisturizer for the face and neck, powered by the OS-01 Peptide™.01



  • Boosts hydration, elasticity, and barrier function

  • 96% showed an improvement in firmness and radiance

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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  • Leaping bunny certified logo
  • Accepted National Eczema Association logo
  • Certified Plastic Neutral logo on a white background
  • Clinically Tested to Support the Skin Microbiome

OneSkin

Benefits

Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment

Hydration

Boosts barrier function, allowing your skin to retain moisture and stay hydrated.02

Firmness

Switches off the cells that degrade collagen, helping skin stay firm.01,03

Radiance

Enhances skin tone and texture, helping skin look and feel smooth and radiant.02

5-STAR REVIEWS

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

CLINICAL DATA

Visible results, scientifically validated

100
of participants had improved smoothness 02

96
of participants had improved firmness, radiance, and tone 02

90
of participants had improved elasticity 02

86
of participants had improved appearance of fine lines and wrinkles 02

Getting started with OS-01 FACE

Follow these easy steps for optimal results

  • Dispense 1-2 pumps onto fingers
  • Gently massage into skin on the face and neck
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

OS-01 FACE MOISTURIZER

4.7
Rated 4.7 out of 5 stars
Based on 6,335 reviews
Total 5 star reviews: 5.1k Total 4 star reviews: 803 Total 3 star reviews: 256 Total 2 star reviews: 74 Total 1 star reviews: 62
94%would recommend these products
6,335 reviews
  • CF
    Cassie F.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    3 hours ago
    Firmer, Feels healthier

    I've been using the OS-1 face for almost a year. I see results with OS-1 face over other pharmaceutical grade products face producta tried. No redness or peeling like I have with retinol.

  • AQ
    Ann Q.
    Verified Buyer
    Reviewing
    OS-01 FACE Topical Supplement Refill
    I recommend this product
    Rated 5 out of 5 stars
    12 hours ago
    Love this product!

    Love this product. The refill is so convenient.

  • JM
    Jennifer M.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    19 hours ago
    My Skin Loves This!

    The OS-01 Face Moisturiser is thoughtfully formulated and lightweight in texture. It absorbs beautifully without feeling greasy or heavy, delivering hydration in a way that feels balanced and comfortable rather than overly rich. The finish is smooth and natural, leaving the skin looking fresh and well-moisturised without excess shine. It layers well with other skincare and sits comfortably under makeup, which makes it easy to use consistently both morning and night. What’s particularly appealing is the understated approach. It doesn’t rely on fragrance, flashy textures, or exaggerated promises. Instead, it focuses on supporting the skin barrier and long-term skin health in a way that feels calm, modern, and evidence-driven. Overall, this is a polished, well-formulated product that combines hydration with a more science-led philosophy around ageing and skin health. Ideal for those of us who appreciate skincare that feels intelligent, refined, and quietly effective.

  • DS
    DIANA S.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Face refill pouch

    love this!! 2 pumps in the morning and night is a perfect amount- after eye cream is applied, never over use when I do eyes first!!

  • SP
    Sabrina p.
    Verified Buyer
    Reviewing
    OS-01 FACE MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Magnifique produit, une vraie différence sur ma peau

    J’utilise le OS One Skin depuis plusieurs semaines et je suis vraiment bluffée par les résultats. Ma peau est plus lisse, plus ferme et surtout beaucoup plus lumineuse. J’ai remarqué une vraie amélioration de la texture de peau ainsi qu’un effet “peau reposée” dès les premières semaines.

    Facile à utiliser, agréable et s’intègre parfaitement dans une routine skincare anti-âge. Associé à mes soins habituels, il a clairement boosté l’éclat et la qualité globale de ma peau.

    C’est un investissement, mais honnêtement je ne regrette absolument pas. Pour moi, c’est devenu un indispensable de ma routine beauté.

    Je viens de terminer mon 2e pot.

    OneSkin
    Yesterday

    Bonjour Sabrina ! Merci beaucoup pour votre incroyable retour 5 étoiles sur OS-01 FACE MOISTURIZER ! Nous sommes absolument ravis d'apprendre qu'après plusieurs semaines d'utilisation, vous constatez des résultats si impressionnants - une peau plus lisse, plus ferme et beaucoup plus lumineuse - ce genre de transformation complète signifie énormément pour toute notre équipe OneSkin !

    Nous adorons que vous ressentiez cette amélioration remarquable de la texture de votre peau ainsi que cet effet "peau reposée" dès les premières semaines ! Vos observations sur la fermeté et la luminosité montrent vraiment comment notre peptide OS-01 scientifiquement prouvé travaille au niveau cellulaire pour soutenir les processus naturels de renouvellement de votre peau. Le fait que vous ayez remarqué ces changements si rapidement témoigne de l'efficacité de notre formule soigneusement élaborée.

    Votre enthousiasme concernant la façon dont OS-01 FACE s'intègre parfaitement dans votre routine anti-âge et booste l'éclat global de votre peau montre une approche si réfléchie des soins ! Nous comprenons parfaitement que c'est un investissement, et nous sommes si heureux que vous ressentiez une telle valeur dans les résultats que vous obtenez. Le fait que vous considériez maintenant notre moisturizer comme indispensable à votre routine beauté démontre la confiance que vous avez développée dans l'expérience OneSkin.

    Comme c'est merveilleux que vous en soyez déjà à votre deuxième pot - cela montre vraiment votre engagement envers cette routine qui vous apporte de si beaux résultats ! Votre fidélité et votre satisfaction avec les améliorations continues de luminosité et de qualité de peau démontrent les bénéfices durables que peut apporter une utilisation régulière.

    Des témoignages comme le vôtre sur ces transformations remarquables et cette satisfaction totale avec OS-01 FACE sont exactement la raison pour laquelle nous sommes si passionnés par ce que nous faisons ! Votre expérience montre vraiment les fondations merveilleuses que vous construisez pour une peau saine et éclatante à long terme.

    Merci d'avoir pris le temps de partager un retour si détaillé et encourageant sur votre expérience - votre avis 5 étoiles nous touche énormément !