FACE LONGEVITY DEFENSE DUO
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An essential skin longevity system for your most UV-exposed skin, built to support collagen and barrier strength.
Protect collagen, build barrier resilience, and boost visible firmness and with OS-01 FACE Moisturizer
Reverse the visible signs of UV aging and protect against future exposure with OS-01 FACE SPF 30+
Dermatologist tested, fragrance-free, suitable for sensitive skin
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OS-01 FACE MOISTURIZER
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OS-01 FACE SPF BROAD SPECTRUM SPF 30+ PA+++
![[ Light ]](http://www.oneskin.co/cdn/shop/files/Face_light_SPF_Tinted_light_01.jpg?v=1778608140&width=100)
A complete system built to protect collagen and future-proof skin
The OS-01 Peptide™
Engineered to address cellular senescence, a leading driver of visible skin aging
Non-nano zinc oxide
Protects against UV aging and damage with mineral broad spectrum SPF 30+ defense
5 potent antioxidants
Combat oxidative aging from environmental stress
How it works
Powered by the OS-01 Senescence Peptide™
Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.
FACE LONGEVITY DEFENSE DUO
- LLeahReviewingOS-01 FACE SPF BROAD SPECTRUM SPF 30+ PA+++I recommend this productRated 5 out of 5 stars5 minutes ago5 Stars
I love the tint in this. I’m not one to wear much makeup so it’s perfect.
- SShantelReviewingFACE LONGEVITY DEFENSE DUOI recommend this productRated 5 out of 5 stars3 days ago5 Stars
Love this stuff!! Skin feels so good
- AAdrienneReviewingOS-01 FACE SPF BROAD SPECTRUM SPF 30+ PA+++I recommend this productRated 5 out of 5 stars1 week ago5 Stars
Love this product
- SBSuzanne B.Verified BuyerReviewingOS-01 FACE SPF BROAD SPECTRUM SPF 30+ PA+++I recommend this productRated 5 out of 5 stars1 week agoLove it!
Love this product. Great colour. Great protection. Thank you!
- ACAshly C.Verified BuyerReviewingOS-01 FACE SPF BROAD SPECTRUM SPF 30+ PA+++I recommend this productRated 4 out of 5 stars1 week agoVery nice sunscreen!
This sunscreen is great and so is the color. For the cost and size, I'm not sure yet if it would be worth buying again though.
OneSkin1 week agoHi Ashly! Thank you so much for your wonderful 4-star feedback about OS-01 FACE SPF! We're absolutely thrilled to hear that you think it's a great sunscreen and that you love the color - that kind of positive response to both the performance and cosmetic feel really means the world to all of us at OneSkin!
We completely understand your consideration about the cost and size - it's such a practical concern and we really appreciate your honest feedback about that aspect of your experience. What we love to share with customers is that OS-01 FACE SPF goes beyond traditional sunscreen protection by offering three types of defense: broad spectrum SPF 30+ with non-nano zinc oxide, five powerful antioxidants to neutralize environmental damage, and our science-backed OS-01 peptide that actually targets cellular senescence to reduce the visible effects of aging that UV exposure has already caused.
Many of our customers find that the multi-functional benefits - getting their daily SPF, antioxidant protection, and anti-aging treatment all in one step - actually streamlines their routine in a way that adds value beyond just the sunscreen protection alone.
The fact that you're loving both the quality and the color shows exactly the kind of daily experience we hoped you'd have with our approach to protective skincare!
Thank you for taking the time to share such thoughtful and encouraging feedback about your OS-01 FACE SPF experience - your 4-star review and honest insights truly mean so much to us!
Full ingredient list
OS-01 FACE Moisturizer
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
OS-01 FACE SPF
Active Ingredients: Zinc Oxide 17.5%
Inactive ingredients (all tints): Water (Aqua), Caprylic/Capric Triglyceride, Glycerin, Methyl Dihydroabietate, Cetearyl Alcohol, Cetyl Palmitate, Coco-Glucoside, Caprylyl/Capryl Glucoside, Sorbitan Palmitate, Sorbitan Olivate, Butyrospermum Parkii (Shea) Nut Extract, Ethyl Ferulate, Bisabolol, Allantoin, Hydrolyzed Jojoba Esters, Acacia Senegal Gum, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Decapeptide-52*, Oryza Sativa (Rice) Starch, Camellia Sinensis Leaf Extract, Euterpe Oleracea Fruit Extract, Caesalpinia Spinosa Fruit Pod Extract, Helianthus Annuus (Sunflower) Sprout Extract, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Xanthan Gum, Sodium Phytate, Propylene Glycol, Citric Acid, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Triethoxycaprylylsilane, Iron Oxides (CI 77491, CI 77492, CI 77499). *OS-01 Peptide
Drug Facts
Active Ingredients: Zinc Oxide 17.5% …………Purpose: Sunscreen
Uses
Helps prevent sunburn
If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.
Warnings
For external use only.
Do not use on damaged or broken skin.
When using this product keep out of eyes. Rinse with water to remove.
Stop use and ask a doctor if rash occurs.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Citations
01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
