BODY LONGEVITY DEFENSE DUO
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An essential skin longevity system for your most underprotected skin, built to support collagen and barrier strength.
Prevent UV-induced collagen loss, build barrier resilience, and boost visible firmness and with OS-01 BODY Moisturizer
Reverse the visible signs of UV aging and protect against future exposure with OS-01 BODY SPF 30+
Dermatologist tested, fragrance-free, suitable for sensitive skin
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OS-01 BODY MOISTURIZER
OS-01 BODY SPF BROAD SPECTRUM SPF 30 PA+++
A complete system built to protect collagen and future-proof skin
The OS-01 Peptide™
Engineered to address cellular senescence, a leading driver of visible skin aging
Non-nano zinc oxide
Protects against UV aging and damage with mineral broad spectrum SPF 30+ defense
4 potent antioxidants
Combat oxidative aging from environmental stress
How it works
Powered by the OS-01 Senescence Peptide™
Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.
BODY LONGEVITY DEFENSE DUO
- SWSandy W.Verified BuyerReviewingOS-01 BODY MOISTURIZERI recommend this productRated 5 out of 5 stars4 minutes agoLove it!
Perfect consistency. Body Moisturizer is not thick or sticky.
- VVVeronica V.Verified BuyerReviewingOS-01 BODY MOISTURIZERI recommend this productRated 5 out of 5 stars13 hours agoSofter skin
I noticed a smooth and glowing skin. It doesn’t feel greasy all all
- DEDeborah E. R.Verified BuyerReviewingOS-01 BODY MOISTURIZERI recommend this productRated 5 out of 5 starsYesterdayWOW. I heard my skin approve
It's not made of velvet?! This is my skin's miracle lotion. It provides what it was needed to bring it to a healthful condition, even soft, not temporarily soft, never irritated, itchy, dry. Love it.
- SWSherri W.Verified BuyerReviewingOS-01 BODY MOISTURIZERI recommend this productRated 5 out of 5 starsYesterdayLove It!
My skin has never looked so good! It feels and looks hydrated all day long. I've noticed I have a firmer and smoother skin texture. 10 out of 10 !
- PPPaulina P.Verified BuyerReviewingOS-01 BODY MOISTURIZERI recommend this productRated 4 out of 5 stars2 days agoSo far so good
Dramatic changes not yet I hope that with time those changes are noticeable. Got this product because my skin is getting super thin. Going through perimenopause and seeing a lot of symptoms one of them is my struggle with my skin.
OneSkinYesterdayHi Paulina! Thank you so much for your thoughtful 4-star feedback about OS-01 BODY MOISTURIZER! We're really glad to hear that things are going well so far - that kind of positive early experience means a lot to all of us at OneSkin!
We really appreciate you sharing what's going on with your skin right now. The fact that you're being patient with the process and giving OS-01 BODY MOISTURIZER time to work shows exactly the kind of realistic approach that helps you get the most out of your skincare routine. Consistent use over time is really key, and we love that you're committed to seeing how it continues to support your skin.
Your thoughtful consideration of how this product might help address your skin concerns is exactly the kind of feedback that matters to us - thank you for trusting OneSkin to be part of your skincare journey during this time.
Thank you for taking the time to share your feedback about OS-01 BODY MOISTURIZER - your 4-star review truly means so much to us, and we're excited to hear how you continue to experience it!
Full ingredient list
OS-01 BODY Moisturizer
Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide
OS-01 BODY SPF
Active Ingredients: Zinc Oxide 14%
Inactive ingredients:Caprylic/Capric Triglyceride, Butyloctyl Salicylate, C13-15 Alkane, Stearalkonium Hectorite, Coconut Alkanes, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Propylene Carbonate, Quaternium-90 Bentonite, Butyrospermum Parkii Nut Extract, Decapeptide-52*, Camellia Oleifera (Tea) Seed Oil, Caesalpinia Spinosa Fruit Pod Extract, Helianthus Annuus (Sunflower) Sprout Extract, Aloe Barbadensis Leaf Extract, Carthamus Tinctorius Seed Oil, Lactobacillus/Acerola Cherry Ferment, Coco-Caprylate/Caprate, Ceramide NP, Ceramide AP, Ceramide EOP, Ethylhexylglycerin, Caprylyl Glycol, Hexylene Glycol, Polyhydroxystearic acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Carbomer, Xanthan gum, Water, Propylene Glycol, Triethyl Citrate, Citric Acid, Sodium Benzoate, and Phenoxyethanol.*OS-01 Peptide
Drug Facts
Active Ingredients: Zinc Oxide 14% …………Purpose: Sunscreen
Uses
Helps prevent sunburn
If used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun.
Warnings
For external use only.
Do not use on damaged or broken skin.
When using this product keep out of eyes. Rinse with water to remove.
Stop use and ask a doctor if rash occurs.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Drug Facts
01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
