Body Longevity Defense Duo
Full Size
Body Longevity Defense Duo
OS-01 FACE + OS-01 BODY
Full Size
- Unit price
- per
An essential skin longevity system for your most underprotected skin, built to support collagen and barrier strength.
Prevent UV-induced collagen loss, build barrier resilience, and boost visible firmness and with OS-01 BODY Moisturizer
Reverse the visible signs of UV aging and protect against future exposure with OS-01 BODY SPF 30+
Dermatologist tested, fragrance-free, suitable for sensitive skin
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Limited Edition OneSkin Bag
OS-01 BODY MOISTURIZER
OS-01 BODY SPF BROAD SPECTRUM SPF 30 PA+++
A complete system built to protect collagen and future-proof skin
The OS-01 Peptide™
Engineered to address cellular senescence, a leading driver of visible skin aging
Non-nano zinc oxide
Protects against UV aging and damage with mineral broad spectrum SPF 30+ defense
4 potent antioxidants
Combat oxidative aging from environmental stress
How it works
Powered by the OS-01 Senescence Peptide™
Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.
Body Longevity Defense Duo
- BUBruce U.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 stars3 minutes agoCrepe skin
Before OneSkin, I had creepy skin on my legs. Since OneSkin body, I don’t have any creepy skin anymore. My massage therapist tells me that I have the best skin of any of her clients.
- M'Marilyn '. P.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 stars3 hours ago50 STARS for OS-01 Body Lotion!!!!!!!!!!
50 STARS for OS-01 Body Lotion!!!!!!
I recall my initial skepticism when I had first read about OS-01 Body lotion on AGEIST Blog. However, after further research into the company, I decided to test the product as no other alternatives had shown any results. It was a $plurge treat ... or so I convinced myself.
The Lotion did NOT disappoint. RESULTS are apparent, cumulative, and most welcome self-care. SILKY SMOOTH SKIN. The Body Moisturizer has also improved the strength of my fingernails as well as softened a surgical scar. I am a huge fan of the entire OS-01 Collection… an ABSOLUTE MUST for Self-Care.
One Skin succeeds where other products do not measure up.
Kudos OS-01!
- JOJennifer O.Verified BuyerReviewingOS-01 BODY MOISTURIZERI recommend this productRated 5 out of 5 stars20 hours agoBest body moisturizer I’ve ever used
After a couple of uses my dry scaley skin greatly improved and hyperpigmentation noticeably lightened
- RBRebecca B.Verified BuyerReviewingOS-01 BODY MOISTURIZERI recommend this productRated 5 out of 5 stars20 hours agoOS daily moisturizer
I’ve been using the daily moisturizer for 2 wks and I’m already seeing a difference in my crepey skin.
- MRMarla R.Verified BuyerReviewingOS-01 BODY MOISTURIZERI recommend this productRated 5 out of 5 stars23 hours agoAmazing Moisturizer for Crepey Skin
I am blown away by the initial results of the OS-01 Body Moisturizer from One Skin and look forward to seeing further improvements with continued use. I have been searching for a product to relieve/eliminate my aging, crepey skin for years, and I finally found a winner! If you are even thinking about purchasing this product for a similar issue, don't hesitate to try it. Truly shocked by the results.
Full ingredient list
OS-01 BODY Moisturizer
Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide
OS-01 BODY SPF
Active Ingredients: Zinc Oxide 14%
Inactive ingredients:Caprylic/Capric Triglyceride, Butyloctyl Salicylate, C13-15 Alkane, Stearalkonium Hectorite, Coconut Alkanes, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Propylene Carbonate, Quaternium-90 Bentonite, Butyrospermum Parkii Nut Extract, Decapeptide-52*, Camellia Oleifera (Tea) Seed Oil, Caesalpinia Spinosa Fruit Pod Extract, Helianthus Annuus (Sunflower) Sprout Extract, Aloe Barbadensis Leaf Extract, Carthamus Tinctorius Seed Oil, Lactobacillus/Acerola Cherry Ferment, Coco-Caprylate/Caprate, Ceramide NP, Ceramide AP, Ceramide EOP, Ethylhexylglycerin, Caprylyl Glycol, Hexylene Glycol, Polyhydroxystearic acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Carbomer, Xanthan gum, Water, Propylene Glycol, Triethyl Citrate, Citric Acid, Sodium Benzoate, and Phenoxyethanol.*OS-01 Peptide
Drug Facts
Active Ingredients: Zinc Oxide 14% …………Purpose: Sunscreen
Uses
Helps prevent sunburn
If used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun.
Warnings
For external use only.
Do not use on damaged or broken skin.
When using this product keep out of eyes. Rinse with water to remove.
Stop use and ask a doctor if rash occurs.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Drug Facts
01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
