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OS-01 LIP SPF 15

4.5
4.5 out of 5
4.5 (388)

12 mL / 0.41 fl oz

Instant hydration and UV defense for vulnerable lips, powered by the OS-01 Peptide™ to support long-term health and resilience.



  • Protects against 3 main drivers of lip skin aging

  • Hydrating, smooth, non-sticky mineral SPF protection

  • Available in untinted or semi-sheer Bare Blush to enhance natural lip tone

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  • Leaping bunny certified logo
  • Accepted National Eczema Association logo

THE LIP TRIFECTA

Three benefits. Two seconds. OneSkin.

Cellular support, UV protection, and instant hydration—all in a semi-sheer tint you’ll want to wear all day.

OneSkin

Formulated with ingredients designed to target the main drivers of aging in lip skin.


OS-01 Peptide™

Engineered to address a leading driver of visible aging


Non-nano zinc oxide
Protects against UV aging and damage with mineral broad spectrum SPF 15+ defense


6 antioxidants
Combat oxidative aging from environmental stress

OneSkin

Formulated with ingredients designed to target the main drivers of aging in lip skin.


OS-01 Peptide™

Engineered to address a leading driver of visible aging


Non-nano zinc oxide
Protects against UV aging and damage with mineral broad spectrum SPF 15+ defense


6 antioxidants
Combat oxidative aging from environmental stress

5-star reviews

See why customers love OS-01 LIP SHIELD SPF 15+

“My lips appear plumper and deeper in color in an incredibly healthy and youthful appearance. I have tried high end and low end brands and nothing compares to the efficacy of this product.” – Caroline W.

"My lips have constantly felt softer. And I also had a special case because I had an eczema patch on my lips before I started using this product, and I was worried it would make it worse but it actually made it better! My eczema patch cleared up after a couple weeks of use. Huge fan of this product overall.” – Victoria Z.

“This definitely helped my chronically dry and chapped lips. I would make this my go to moving forward.” – Adam P.

5-star reviews

See why customers love OS-01 LIP SHIELD SPF 15+

“My lips appear plumper and deeper in color in an incredibly healthy and youthful appearance. I have tried high end and low end brands and nothing compares to the efficacy of this product.” – Caroline W.

"My lips have constantly felt softer. And I also had a special case because I had an eczema patch on my lips before I started using this product, and I was worried it would make it worse but it actually made it better! My eczema patch cleared up after a couple weeks of use. Huge fan of this product overall.” – Victoria Z.

“This definitely helped my chronically dry and chapped lips. I would make this my go to moving forward.” – Adam P.

CONSUMER PERCEPTION DATA

Real results that speak volumes

92
agree it delivers immediate hydration and moisture 01

88
agree it makes their lips feel soothed and protected 01

84
agree their lips felt nourished after 2 weeks 01

78
agree it provides long-lasting hydration and moisture 01

CONSUMER PERCEPTION DATA

Real results that speak volumes

92
agree it delivers immediate hydration and moisture 01

88
agree it makes their lips feel soothed and protected 01

84
agree their lips felt nourished after 2 weeks 01

78
agree it provides long-lasting hydration and moisture 01

How it works

Powered by the OS-01 Senescence Blocking Peptide™

Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin aging, supporting meaningful improvements in skin health today and over time to future-proof skin.

OS-01 LIP SPF 15

4.5
Rated 4.5 out of 5 stars
Based on 388 reviews
Total 5 star reviews: 301
Total 4 star reviews: 41
Total 3 star reviews: 16
Total 2 star reviews: 14
Total 1 star reviews: 16
88%would recommend these products
388 reviews
  • HK
    Houman K.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    Love it

    A bit of shine but I don't mind it. Love the moisture it delivers.

  • JF
    Julie F.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 5 out of 5 stars
    8 hours ago
    Perfect color work daily protection

    I’m in love with this blush lip SPF. It’s my daily obsession and I won’t go outside without it. Smooth and hydrated lips without the stickiness. One skin does it again!

  • PC
    Pamela C.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 5 out of 5 stars
    13 hours ago
    OS-01 LIP SPF15

    Live 10 minutes from the Gulf and go all the time. Best lip balm I have tried and have tried MANY! LOVE that it’s fragrance free

  • MT
    Marianne T.
    Verified Buyer
    Reviewing
    OS-01 LIP SHIELD BARE BLUSH, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Love this

    The color and texture is perfect- no flavor and applies easily

  • LO
    Lara O.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF 15
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    No taste, for reals!

    I keep multiple tubes of this SPF so I’m never anywhere without it. The color is gorgeous and the finish is so comfortable and perfect. Not sticky at all, just comforting and long-lasting. No SPF taste, the best part!

    OneSkin
    11 hours ago

    Hi Lara! Thank you so much for your wonderful 5-star feedback about our OS-01 LIP SPF 15! We're absolutely thrilled to hear that you're loving it - that kind of enthusiastic response really means the world to all of us at OneSkin!

    It's fantastic that you're keeping multiple tubes on hand, and we're so grateful to hear that the color is gorgeous and the finish is so comfortable and perfect for you. The fact that you're experiencing a non-sticky, long-lasting feel is exactly the kind of seamless experience we hope our lip care delivers, and knowing that there's no SPF taste is incredibly encouraging feedback!

    Thank you for taking the time to share such wonderful feedback about your OS-01 LIP SPF 15 experience - your 5-star review truly means so much to us!

All ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive Ingredients: Simmondsia, Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Beta-Sitosterol, Squalene, Lactic Acid, Palmitic acid. *OS-01 Peptide

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

All ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive ingredients: Simmondsia Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae rhamnoides (Sea Buckthorn) Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic Acid, Lecithin, Lactic Acid, Octyldodecanol, Sorbitan Oleate, Alumina, Magnesium Oxide, Palmitic Acid, Iron oxides (CI 77491, CI 77492, CI 77499), Titanium Dioxide (CI 77891), Red 33 Lake (CI 17200), Red 7 Lake (CI 15850).

Drug Facts

Active Ingredients: Zinc Oxide 5.5% …………Purpose: Sunscreen

Uses

  • Helps prevent sunburn
  • If used as directed with other sun protection measures (see directions), decreases the risk of skin cancer and early skin aging caused by the sun.

Warnings

  • For external use only.
  • Do not use on damaged or broken skin.
  • Stop use and ask a doctor if rash occurs.
  • Keep out of reach of children.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
02 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03 Zonari A.,et al.Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation.J Cosmet Dermatol.2024; 23: 2135-2144. doi:10.1111/jocd.16242