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OS-01 LIP Duo

4.5
4.5 out of 5
4.5 (641)

The only 24-hour system powered by the OS-01 Peptide™ to shield and restore your lips at the cellular level01.



  • OS-01 LIP SPF protects against UV and cellular aging by day

  • OS-01 LIP Mask promotes collagen, elastin, and hyaluronic acid at night


  • Dermatologist tested, fragrance-free, safe for sensitive skin


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OS-01 LIP SPF

Daytime:

Gently squeeze a small amount of OS-01 LIP SPF onto the applicator tip and apply a thin layer directly to lips prior to sun exposure.

OS-01 LIP Mask

Nighttime:

Using the metal applicator, apply a generous layer of OS-01 LIP Mask onto clean, dry lips before bed and leave on overnight.

*Applies clear. Due to natural ingredients, color in compact may vary slightly.

HOW OS-01 WORKS

The science to unlock your healthiest skin

Backed by over a decade of longevity research, the OS-01 Peptide™ targets the cells that speed up the visible signs of aging.02

OS-01 is scientifically proven to:

  • Support repair by reducing the buildup of senescent “zombie” cells
  • Improve how skin behaves, stimulating collagen and hyaluronic acid production
  • Build resilience, keeping your skin healthy and youthful as you age

Full ingredient list

OS-01 LIP SPF ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive Ingredients: Simmondsia, Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Beta-Sitosterol, Squalene, Lactic Acid, Palmitic acid. *OS-01 Peptide™

OS-01 LIP MASK ingredients

Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan. *OS-01 Peptide™

OS-01 LIP Duo

4.5
Rated 4.5 out of 5 stars
Based on 641 reviews
Total 5 star reviews: 499 Total 4 star reviews: 54 Total 3 star reviews: 43 Total 2 star reviews: 25 Total 1 star reviews: 20
86%would recommend these products
641 reviews
  • KK
    KELLY K.
    Verified Buyer
    Reviewing
    OS-01 LIP SPF BROAD SPECTRUM SPF 15+
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Loving this!

    Speaking as a woman who is in menopause - dry lips suddenly became a 'THING'! I am loving the instant moisture and lasting soothing feeling that this balm is giving me.

  • MW
    Marianne W.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    1 hour ago
    Use Every Night

    Great product and my lips feel better each day that the Lip Mask is used.

  • BJ
    Barbara J.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    4 hours ago
    Best Lip Mask and SPF Duo

    The texture of my lips have improved significantly using these in combination.

  • R
    Rebecca
    Reviewing
    OS-01 LIP RESTORE MASK
    I do not recommend this product
    Rated 1 out of 5 stars
    18 hours ago
    1 Star

    Couldn’t figure out how to open the compact so that was an initial issue. I do not like the “applicator.”

    Not practical. Product is okay but will not repurchase.

  • EP
    Ellen P.
    Verified Buyer
    Reviewing
    OS-01 LIP RESTORE MASK
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Really is perfect mask

    I have tried several other nighttime masks, but did not feel that they had staying power. This one works for me.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
02 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1