OS-01 FACE Topical Supplement Refill
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- Suited to All skin types, safe for sensitive skin
- Targets Dehydration, dullness, loss of elasticity
- Format Lightweight moisturizer
**Reusable plastic shell not included**
The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.
Benefits
Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment
Hydration
Boosts barrier function, allowing your skin retain moisture and stay hydrated.02
Firmness
Switches off the cells that degrade collagen, helping skin stay firm.01,03
Radiance
Enhances skin tone and texture, helping skin look and feel smooth and radiant.02
5-STAR REVIEWS
See why customers love OS-01 FACE
βI stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smoothβ¦and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.β β Tova N.
"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" β Laura E.
"Itβs working great!!! It absorbs quickly. I see and feel a significant difference in my skinβs texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." β Ildiko C.
"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." β Sarah B.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
100
of participants had improved smoothness 02
95.5
of participants had improved firmness, radiance, and tone 02
90
of participants had improved elasticity 02
86
of participants had improved appearance of fine lines and wrinkles 02
The Science Behind OS-01 FACE
With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:
- Increases epidermal thickness 01
- Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 01,03
- Promotes cellular proliferation (increase in MKI67) 01
Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE
6 active ingredients that complement the OS-01 peptide
Getting started with OS-01 FACE
Follow these easy steps for optimal results
- Dispense 1-2 pumps onto fingers
- Gently massage into skin on the face and neck
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Peptideβ’
The only peptide scientifically proven to reverse skin aging at the cellular levelΒ 01,02,03
All Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age Β and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
OS-01 FACE Topical Supplement Refill
- PMPaul M.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars4 minutes agoIndispensable
Iβve been using OneSkin since it launched. Canβt live without it.
- CCaseyReviewingOS-01 FACE Topical SupplementI recommend this productRated 5 out of 5 stars1 hour ago5 Stars
Evens put my skin tone and makes it feels soft! Seems to be having a noticeable effect on wrinkles as well.
- SShaneReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars3 hours ago5 Stars
The Great OneSkin OS-01 face is wonderful and backed by science. Been using this product for 2 years. My skin is flawless as a man, age 55. People ask me how i look so young. I work at the airlines and get asked every flight! Ty OneSkin
- TKTai K.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars7 hours agoLove it so far!
My skin is clear, and wrinkles are less. Supposed to get botox coming up and may wait for a month or so.
- LDLidija D.Verified BuyerReviewingReplacement OS-01 FACE Refill PouchI recommend this productRated 5 out of 5 starsYesterdayOS-01 Face (refill)
I like the consistency, smell (or lack of it) and puracy of this cream. Applies well, absorbs nicely, and makes my mature skin (58 yrs young) feel hydrated and soft. Cannot tell how much it reduces the lines/wrinkles, but overall my skin looks healthier, and potentially more youthful. Also reduces redness/irritation. I've been using it on and off, lately more consistently, for about a year.
OneSkin5 hours agoHi Lidija!
Thank you for the review! We are happy to hear you are enjoying OS-01 FACE!
