OS-01 EYE Topical Supplement
OS-01 EYE Topical Supplement
OS-01 EYE is a targeted skin longevity treatment with the highest concentration of the OS-01 Senescence Blocking Peptide™, scientifically proven to support the ultra-delicate skin around the eyes.01
SUBSCRIPTION EXCLUSIVES
- Plastic neutral refillable packaging
- Exclusive early access to new products
- Earn 2x points on all recurring orders
- Easily change, skip or cancel anytime
✭ You’re earning 98 points with OneSkin Loyalty Program ✭
Try it risk-free! 45 day money back guarantee.
- Targets Dehydration, loss of elasticity, wrinkles
- Suited to All skin types, safe for sensitive skin
- Format Rich eye cream
BENEFITS
Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 02
Wrinkle reduction
Boosts collagen to visibly smooth lines and wrinkles.01,03
Firmness
Supports skin health for a firmer, more lifted appearance.03
Hydration
Strengthens the skin barrier to lock in moisture and keep skin hydrated.03
5-star reviews
See why customers love OS-01 EYE
“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.
"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.
"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.
"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
95.5
of participants reported improved texture and tone 03
90.9
of participants reported improved radiance 03
87.5
of participants showed improved hydration 03
86
of participants had improved elasticity 03
The Science Behind OS-01 EYE
The skin around the eyes is among the thinnest on the body, making it exceptionally delicate and prone to aging.04 This vulnerability leads to higher levels of cellular senescence,02 leaving the eye area more susceptible to sagging and wrinkles.
OS-01 EYE was specifically designed to address the unique needs of this fragile skin, delivering the highest concentration of our OS-01 peptide for unparalleled skin health benefits.
In lab studies, our scientists analyzed key aging biomarkers in human skin samples before and after treatment. Their findings show that OS-01 EYE:
- Promotes collagen retention (decrease in MMP1)01
- Reduces a key biomarker associated with cellular senescence (CDKN2A)01
- Lowers a key biomarker linked to inflammation (IL-8)01
Shown in lab studies on ex vivo human eyelid skin samples by analyzing levels of collagen in skin treated with OS-01 EYE compared to no treatment. Skin treated with OS-01 EYE displayed a significant increase compared to skin with no treatment.
3 active ingredients complement the OS-01 peptide
Getting started with OS-01 EYE
Follow these easy steps for optimal results
- Dispense 1 pump onto tip of finger
- Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.05
All Ingredients
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
Citations
01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
02 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
03 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
OS-01 EYE Topical Supplement
- MSMichelle S.Verified BuyerReviewingOS-01 EYE Topical Supplement RefillI recommend this productRated 5 out of 5 stars3 minutes agoExcellent packaging to get the most product use
This was the first refill for the eye cream that I have bought. When my old one ran out, I was very surprised at how little was actually left in the container. I feel like I truly got my moneys worth of the product. Being able to buy a refill is great less waste. Ice cream is exceptional as always!
- BWBettina W.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 stars12 hours agoPerfect for sensitive eyes
I’ve been using this eye cream for more than 6 months. It has really helped to minimize dryness in the creases of my eyelids and the outer corners of my eyes. Additionally, it does not aggravate my sensitive eyes.
- JCJane C.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 starsYesterdayOS-O1 Eye Cream refill
Great product and I appreciate that you offer a refill option and the ability to reuse outer packaging!
- FSFred S.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 stars2 days agoNot cheapening out. Just economical
At first, I was taken aback by the “refill” not including the full container. Last night, I made the easy change of eye tube and approve.
OneSkinYesterdayHi Fred!
Thank you for the review! We are happy to hear you are enjoying OS-01 EYE!
In an environmentally conscious approach for our subscription system, we only send the outer shell in the first order to reduce waste! We are glad to hear you were able to change out the refll with ease.
- BCBrooke C.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 stars2 days agoHow do you know?
I keep buying it. I think I believe in this company and the science I’m gonna keep going with it. I don’t know how you can really tell much of a difference of it with all this stuff but I’m gonna keep doing it. I’m thankful for one skin, it feels good.
