OS-01 EYE Topical Supplement
OS-01 EYE Topical Supplement
OS-01 EYE is a targeted skin longevity treatment with the highest concentration of the OS-01 Senescence Blocking Peptide™, scientifically proven to support the ultra-delicate skin around the eyes.01
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- Targets Dehydration, loss of elasticity, wrinkles
- Suited to All skin types, safe for sensitive skin
- Format Rich eye cream
BENEFITS
Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 02
Wrinkle reduction
Boosts collagen to visibly smooth lines and wrinkles.01,03
Firmness
Supports skin health for a firmer, more lifted appearance.03
Hydration
Strengthens the skin barrier to lock in moisture and keep skin hydrated.03
5-star reviews
See why customers love OS-01 EYE
“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.
"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.
"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.
"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
95.5
of participants reported improved texture and tone 03
90.9
of participants reported improved radiance 03
87.5
of participants showed improved hydration 03
86
of participants had improved elasticity 03
The Science Behind OS-01 EYE
The skin around the eyes is among the thinnest on the body, making it exceptionally delicate and prone to aging.04 This vulnerability leads to higher levels of cellular senescence,02 leaving the eye area more susceptible to sagging and wrinkles.
OS-01 EYE was specifically designed to address the unique needs of this fragile skin, delivering the highest concentration of our OS-01 peptide for unparalleled skin health benefits.
In lab studies, our scientists analyzed key aging biomarkers in human skin samples before and after treatment. Their findings show that OS-01 EYE:
- Promotes collagen retention (decrease in MMP1)01
- Reduces a key biomarker associated with cellular senescence (CDKN2A)01
- Lowers a key biomarker linked to inflammation (IL-8)01
Shown in lab studies on ex vivo human eyelid skin samples by analyzing levels of collagen in skin treated with OS-01 EYE compared to no treatment. Skin treated with OS-01 EYE displayed a significant increase compared to skin with no treatment.
3 active ingredients complement the OS-01 peptide
Getting started with OS-01 EYE
Follow these easy steps for optimal results
- Dispense 1 pump onto tip of finger
- Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.05
All Ingredients
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
Citations
01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
02 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
03 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
OS-01 EYE Topical Supplement
- SSallieReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 stars22 minutes ago5 Stars
Wrinkles around my eye have about disappeared. I am 74 years old, and I have tried several eye creams. One Skin, OS -01 eye cream delivered wrinkles gone, actually lifted my eye lids. I am really impressed with this product.
- SHSherri H.Verified BuyerReviewingOS-01 EYE Topical SupplementI recommend this productRated 5 out of 5 starsYesterdayso far so good
I started using this a few weeks ago and I have to say it does seem to be doing something. After applying my skin appears brighter and firmer around my eyes. I really like that it has no fragance or smell. I am curious to see how it looks after more time has passed. I think I will also try the face and body lotion to see if I get similar results.
- CKCarol K.Verified BuyerReviewingOS-01 EYE Topical SupplementI recommend this productRated 5 out of 5 starsYesterdayOS-01-EYE
Fantastic product! I noticed an immediate change in fine lines and have continued to see progress. It doesn’t allow concealer to settle or bleed either.
Great product! I’m ordering other items as a result of this product.
- NLnina l.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 starsYesterdayOS-01 Eye
I have absolutely loved using the eye cream. My next order could not come soon enough. Thank you!
- MMeganVerified BuyerReviewingOS-01 EYE Topical SupplementI recommend this productRated 5 out of 5 stars3 days agoBelieve the Science
I first heard about this product on a podcast with Dr Stephanie. At first I thought this was just another plug for a new product to in the skin care world. What got me was all the science that was able to back up the product. I'm in my early forties so wrinkles are just starting to set in and tired skin was starting to show. I was starting to get fine creases along the corners of my eyes. I've been using this cream since March around my eyes and I cannot believe the difference that this has made. My lines have smoothed out and my skin seems to have more hydration and those areas. My under eyes were always baggy and had a tinge of purple. That has lessened since using the eye cream.
I have now purchased the face serum in addition to the SPF. I use this daily as part of my skin routine in the a.m. and the p.m..
I only wish I would have took photos before beginning this cream.
