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OS-01 FACE Topical Supplement

OS-01 FACE Topical Supplement

OS-01 FACE is a daily skin longevity treatment with the OS-01 Senescence Blocking Peptide™, scientifically proven to target a root cause of skin aging to promote healthy, youthful skin on the face and neck.01

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  • Plastic neutral refillable packaging
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Try it risk-free! 45 day money back guarantee.

  • Targets Dehydration, dullness, loss of elasticity
  • Suited to All skin types, safe for sensitive skin
  • Format Lightweight moisturizer

OneSkin

Benefits

Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment

Hydration

Boosts barrier function, allowing your skin retain moisture and stay hydrated.03

Firmness

Switches off the cells that degrade collagen, helping skin stay firm.02,03

Radiance

Enhances skin tone and texture, helping skin look and feel smooth and radiant.03

5-STAR REVIEWS

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

CLINICAL DATA

Visible results, scientifically validated

100

of participants had improved smoothness 03

95.5

of participants had improved firmness, radiance, and tone 03

90

of participants had improved elasticity 03

86

of participants had improved appearance of fine lines and wrinkles 03

The Science Behind OS-01 FACE

With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:

  1. Increases epidermal thickness 02
  2. Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 01,02
  3. Promotes cellular proliferation (increase in MKI67) 02


Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE

Getting started with OS-01 FACE

Follow these easy steps for optimal results

  • Dispense 1-2 pumps onto fingers
  • Gently massage into skin on the face and neck
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242


OS-01 FACE Topical Supplement

4.7
Rated 4.7 out of 5 stars
Based on 5,812 reviews
Total 5 star reviews: 4.7k Total 4 star reviews: 752 Total 3 star reviews: 240 Total 2 star reviews: 68 Total 1 star reviews: 57
94%would recommend these products
5,812 reviews
  • OS
    Olga S.
    Verified Buyer
    Reviewing
    OS-01 FACE Topical Supplement Refill
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    Love Love

    This is my second time buying this and I absolutely love that we can purchase the refills. So convenient.

  • MO
    Maggie O.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    4 hours ago
    Just Enough

    It's very light coverage but it goes on nicely, not too dewy not too matte.

  • L
    Lisa
    Reviewing
    OS-01 FACE Topical Supplement
    I recommend this product
    Rated 5 out of 5 stars
    6 hours ago
    5 Stars

    So far so good !

    I like the ligjt texture and my face is feeling smoother.

  • LG
    Lindsay G.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Perfect texture

    I love how the face cream feels on my skin. I haven't noticed a huge difference in fine lines and wrinkles necessarily, but my skin feels nourished and hydrated. I'll keep using the product to see if it makes a difference.

  • NL
    nina l.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    OS-01 Face

    Its super light and glides on your face with ease, absorbs fast too. Great product!