Benefits
Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment
Hydration
Boosts barrier function, allowing your skin retain moisture and stay hydrated.02
Firmness
Switches off the cells that degrade collagen, helping skin stay firm.01,03
Radiance
Enhances skin tone and texture, helping skin look and feel smooth and radiant.02
5-STAR REVIEWS
See why customers love OS-01 FACE
βI stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smoothβ¦and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.β β Tova N.
"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" β Laura E.
"Itβs working great!!! It absorbs quickly. I see and feel a significant difference in my skinβs texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." β Ildiko C.
"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." β Sarah B.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
100
of participants had improved smoothness 02
95.5
of participants had improved firmness, radiance, and tone 02
90
of participants had improved elasticity 02
86
of participants had improved appearance of fine lines and wrinkles 02
The Science Behind OS-01 FACE
With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:
- Increases epidermal thickness 01
- Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 01,03
- Promotes cellular proliferation (increase in MKI67) 01
Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE
6 active ingredients that complement the OS-01 peptide
Getting started with OS-01 FACE
Follow these easy steps for optimal results
- Dispense 1-2 pumps onto fingers
- Gently massage into skin on the face and neck
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Peptideβ’
The only peptide scientifically proven to reverse skin aging at the cellular levelΒ 01,02,03
All Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age Β and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
OS-01 FACE Topical Supplement
- JjaneVerified ReviewerReviewingOS-01 FACE Topical SupplementI recommend this productRated 5 out of 5 stars7 minutes agoThis face cream is amazing
I initially bought my first bottle from one skin. I purchase it on Amazon now because it's just more convenient. I'm 64 years old and I've been using one skin for a year. Recently I've had a setback and I bought a face cream that I really liked but I've noticed that my face is not looking quite as amazing as it did. I know this product is expensive which I hate because I love it so much but I've gone back to it. I have siblings that are younger than me and when they say that my skin and face look amazing I know it is because of this product. That's not to brag, I just realized when I stopped using one skin my face looks wrinkled and droopy, it's lost the plump and brightness that I've been pretty proud of. I'm not an influencer I'm not paid for this it just is an amazing product I just wish they made a bigger bottle!!
- TJTamara J.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars2 days agoOS-01 Face Supplement
I can already tell a difference in using the OS-01 face supplements! I have just received my second shipment with the refill!
- JSJosie S.Verified BuyerReviewingOS-01 FACE Topical Supplement RefillI recommend this productRated 5 out of 5 stars2 days agoLove OS-01 Products
I use the complete line of OS-01 products and notice a difference in the tone and strength of my skin since using these products for 2+ years. I always receive compliments on my skin and acknowledge that OS-01 is reason why.
- EJEllie J.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars2 days agoImpressed with the results and love the eco-friendly refill option!
Iβve been using OneSkin OS-01 FACE for a few months now, and I can honestly say my skin has never felt better: hydrated, smooth, and more radiant. I appreciate that the formula is backed by science and targets skin aging at the cellular level.
This refill pouch is a great, sustainable option. It was easy to use, and I love that I can reduce waste without compromising on quality. Itβs a little pricey, but the results make it worth it. My skin looks healthier and more even-toned, and Iβve noticed a subtle firmness too.
Highly recommend if youβre looking for a clean, effective product that supports long-term skin health, and care about sustainability!
- JGjames g.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars2 days agoGreat
Really seems to work
