JAN 17

_LEARN

/

REFERENCE LAB

Decoding the Connections Between Intrinsic & Extrinsic Aging





_LEARN

/

REFERENCE LAB

JAN 17

Decoding the Connections Between Intrinsic & Extrinsic Aging






You’ve heard it before: aging is inevitable. But have you ever stopped to consider how true that statement really is? It turns out, it’s only half true and breakthroughs in longevity science–including our OS-01 peptide–are making it less true with every passing day. In fact, there are two major types of aging: intrinsic and extrinsic aging. While one is mostly out of our control, the other is almost entirely preventable. Let’s take a closer look at the two types of aging and what we can all do to help our bodies grow older in good health.

What is the difference between extrinsic and intrinsic aging?

Have you ever looked around at your family and noticed some similarities in the way you age? Maybe it’s matching lines around the eyes. Maybe you look at old pictures of your mom or dad and see your own face. What you’re seeing might be more than family resemblance: it could also be physical signs of intrinsic aging. Determined largely by your genetics, intrinsic aging is the predetermined process that your body will undergo over time based on its innate ability to repair damage.

Extrinsic aging is just the opposite: externally modulated aging that occurs as a result of preventable environmental and lifestyle factors. The vast majority of extrinsic aging is a result of UV exposure, but other external factors related to lifestyle like smoking cigarettes or eating a diet high in processed foods also contribute to the acceleration of extrinsic aging. These external aging factors exacerbate intrinsic aging by increasing the rate at which we age.1
Meet

How are extrinsic and intrinsic aging related?

At the heart of both types of aging is cellular senescence: one of the nine hallmarks of aging that longevity scientists now know is central to the aging process. Occurring continuously within our bodies from the moment we are born, senescence is the end stage in a cell’s life cycle when it stops dividing. When we’re young and healthy, senescent skin cells are quickly cleared away and replaced with new cells. But as we get older, more and more senescent cells accumulate. When these senescent skin cells linger, they secrete biochemical signals that induce chronic inflammation, suppress the immune system, and drive neighboring cells into senescence.

Cellular senescence is one of the root causes of genetically programmed intrinsic aging. Preventable extrinsic aging just makes things worse: factors like UV exposure exacerbate the rate of cellular senescence, making it more difficult for our bodies to keep up with the task of repairing damage. When our bodies can no longer repair damage caused by both intrinsic and extrinsic aging factors, it can have systemic impacts–from skin damage to age-related diseases like Alzheimer’s.

What are the visible signs of intrinsic aging vs extrinsic aging?

So how do you know if what you’re seeing in the mirror is a sign of intrinsic aging vs extrinsic aging? To answer that question, scientists have compared the way photoprotected skin–think skin that’s either regularly treated with sunscreen or covered with clothing–ages in comparison to skin that’s been regularly exposed to the sun’s UV rays over a lifetime.

Photoprotected skin, which is primarily subject to intrinsic aging, shows signs of aging mostly at the basal layer–one of the deeper layers of the skin. These signs include diminished cell production in the basal layer, which results in a thinner epidermal layer. Other signs of aging skin include reduced collagen production, lower elastin levels, and diminished levels of oligosaccharide, a substance that helps the skin maintain optimal hydration levels. Visibly, these cellular changes show up as thinner, more fragile skin with dryness, loss of firmness, and fine lines. You might notice this type of aging on your body, where your skin has been protected, or on your face if you have mostly avoided the sun throughout your life.

Photoexposed skin, which is subject to both intrinsic and extrinsic aging, shows slightly different signs of cellular aging. Unlike the thinner epidermis seen in intrinsically aged skin, photoexposed skin shows signs of thickening in the outermost layer of the epidermis, the stratum corneum. Extrinsically aged skin also shows signs of hyperpigmentation, premature wrinkling, and telangiectasia–visible blood vessels on the surface of the skin. For most people, this type of aging shows up as thicker, drier, coarsely wrinkled skin with loss of elasticity and visible dark spots. The most common areas for this type of aging are the face, hands, neck, and chest–areas that have been exposed to the sun chronically over the course of a lifetime.2

How can we prevent intrinsic vs extrinsic aging?

The good news is that most extrinsic aging is preventable. Up to 80% of facial skin aging is caused by UV rays; wearing sunscreen daily and avoiding extended sun exposure is our most powerful tool in preventing extrinsic aging.3 Other lifestyle shifts can also make a difference: avoiding cigarettes and eating a diet high in fresh vegetables and low in processed foods can also help.4 If you live in an urban area, air pollution is another environmental factor to consider. 5When it comes down to how to remove dead skin cells from your face and body as a whole, using an air purifier in your home and regularly cleansing your skin at the end of each day ensures that your skin is clear of pollutants that can trigger cellular senescence.

Because intrinsic aging occurs as a result of our genetics, scientists have long thought that there is little we can do to prevent it. But as the field of longevity science continues to grow, researchers have discovered that prevention is possible.

How the OS-01 peptide can prevent intrinsic & extrinsic aging

Discovered by OneSkin longevity scientists, our OS-01 peptide has been shown to reduce the accumulation of senescent cells* – the central hallmark of intrinsic skin aging. By reducing the accumulation of these cells, the OS-01 peptide – used in our OS-01 FACE and OS-01 BODY topical supplements – helps diminish the burden of both intrinsic and extrinsic aging, extending your body’s ability to keep up with the natural rate of senescence.

This means skin not only looks younger, it also acts like younger skin on a cellular level. Visibly, these benefits can show up as reduced fine lines, smoother skin texture, minimized dark spots, and improved skin firmness – all signs of improved skin health.

* Shown in in vitro fibroblast cultures from patient-derived samples

Key Takeaways:

  • Intrinsic aging is caused by internal genetic factors while extrinsic aging is caused by external factors
  • Intrinsic aging appears as fine lines and loss of firmness while extrinsic aging appears as coarser wrinkles and dark spots.
  • At the heart of both types of aging is cellular senescence, the accumulation of aged cells that trigger skin damage.
  • Extrinsic aging can be prevented by wearing sunscreen, eating healthy, and avoiding cigarettes
  • The OS-01 peptide has the potential to improve overall skin health by preventing intrinsic aging caused by the accumulation of senescent cells (shown in in vitro skin cultures from patient derived samples).

References:

  1. https://platinumdermatology.com.au/articles/extrinsic-vs-intrinsic-ageing-whats-the-difference/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047276
  3. https://platinumdermatology.com.au/articles/extrinsic-vs-intrinsic-ageing-whats-the-difference/
  4. https://biopelle.com/latest-blog-posts/intrinsic-aging-extrinsic-aging-skin/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047276

You’ve heard it before: aging is inevitable. But have you ever stopped to consider how true that statement really is? It turns out, it’s only half true and breakthroughs in longevity science–including our OS-01 peptide–are making it less true with every passing day. In fact, there are two major types of aging: intrinsic and extrinsic aging. While one is mostly out of our control, the other is almost entirely preventable. Let’s take a closer look at the two types of aging and what we can all do to help our bodies grow older in good health.

What is the difference between extrinsic and intrinsic aging?

Have you ever looked around at your family and noticed some similarities in the way you age? Maybe it’s matching lines around the eyes. Maybe you look at old pictures of your mom or dad and see your own face. What you’re seeing might be more than family resemblance: it could also be physical signs of intrinsic aging. Determined largely by your genetics, intrinsic aging is the predetermined process that your body will undergo over time based on its innate ability to repair damage.

Extrinsic aging is just the opposite: externally modulated aging that occurs as a result of preventable environmental and lifestyle factors. The vast majority of extrinsic aging is a result of UV exposure, but other external factors related to lifestyle like smoking cigarettes or eating a diet high in processed foods also contribute to the acceleration of extrinsic aging. These external aging factors exacerbate intrinsic aging by increasing the rate at which we age.1
Meet

How are extrinsic and intrinsic aging related?

At the heart of both types of aging is cellular senescence: one of the nine hallmarks of aging that longevity scientists now know is central to the aging process. Occurring continuously within our bodies from the moment we are born, senescence is the end stage in a cell’s life cycle when it stops dividing. When we’re young and healthy, senescent skin cells are quickly cleared away and replaced with new cells. But as we get older, more and more senescent cells accumulate. When these senescent skin cells linger, they secrete biochemical signals that induce chronic inflammation, suppress the immune system, and drive neighboring cells into senescence.

Cellular senescence is one of the root causes of genetically programmed intrinsic aging. Preventable extrinsic aging just makes things worse: factors like UV exposure exacerbate the rate of cellular senescence, making it more difficult for our bodies to keep up with the task of repairing damage. When our bodies can no longer repair damage caused by both intrinsic and extrinsic aging factors, it can have systemic impacts–from skin damage to age-related diseases like Alzheimer’s.

What are the visible signs of intrinsic aging vs extrinsic aging?

So how do you know if what you’re seeing in the mirror is a sign of intrinsic aging vs extrinsic aging? To answer that question, scientists have compared the way photoprotected skin–think skin that’s either regularly treated with sunscreen or covered with clothing–ages in comparison to skin that’s been regularly exposed to the sun’s UV rays over a lifetime.

Photoprotected skin, which is primarily subject to intrinsic aging, shows signs of aging mostly at the basal layer–one of the deeper layers of the skin. These signs include diminished cell production in the basal layer, which results in a thinner epidermal layer. Other signs of aging skin include reduced collagen production, lower elastin levels, and diminished levels of oligosaccharide, a substance that helps the skin maintain optimal hydration levels. Visibly, these cellular changes show up as thinner, more fragile skin with dryness, loss of firmness, and fine lines. You might notice this type of aging on your body, where your skin has been protected, or on your face if you have mostly avoided the sun throughout your life.

Photoexposed skin, which is subject to both intrinsic and extrinsic aging, shows slightly different signs of cellular aging. Unlike the thinner epidermis seen in intrinsically aged skin, photoexposed skin shows signs of thickening in the outermost layer of the epidermis, the stratum corneum. Extrinsically aged skin also shows signs of hyperpigmentation, premature wrinkling, and telangiectasia–visible blood vessels on the surface of the skin. For most people, this type of aging shows up as thicker, drier, coarsely wrinkled skin with loss of elasticity and visible dark spots. The most common areas for this type of aging are the face, hands, neck, and chest–areas that have been exposed to the sun chronically over the course of a lifetime.2

How can we prevent intrinsic vs extrinsic aging?

The good news is that most extrinsic aging is preventable. Up to 80% of facial skin aging is caused by UV rays; wearing sunscreen daily and avoiding extended sun exposure is our most powerful tool in preventing extrinsic aging.3 Other lifestyle shifts can also make a difference: avoiding cigarettes and eating a diet high in fresh vegetables and low in processed foods can also help.4 If you live in an urban area, air pollution is another environmental factor to consider. 5When it comes down to how to remove dead skin cells from your face and body as a whole, using an air purifier in your home and regularly cleansing your skin at the end of each day ensures that your skin is clear of pollutants that can trigger cellular senescence.

Because intrinsic aging occurs as a result of our genetics, scientists have long thought that there is little we can do to prevent it. But as the field of longevity science continues to grow, researchers have discovered that prevention is possible.

How the OS-01 peptide can prevent intrinsic & extrinsic aging

Discovered by OneSkin longevity scientists, our OS-01 peptide has been shown to reduce the accumulation of senescent cells* – the central hallmark of intrinsic skin aging. By reducing the accumulation of these cells, the OS-01 peptide – used in our OS-01 FACE and OS-01 BODY topical supplements – helps diminish the burden of both intrinsic and extrinsic aging, extending your body’s ability to keep up with the natural rate of senescence.

This means skin not only looks younger, it also acts like younger skin on a cellular level. Visibly, these benefits can show up as reduced fine lines, smoother skin texture, minimized dark spots, and improved skin firmness – all signs of improved skin health.

* Shown in in vitro fibroblast cultures from patient-derived samples

Key Takeaways:

  • Intrinsic aging is caused by internal genetic factors while extrinsic aging is caused by external factors
  • Intrinsic aging appears as fine lines and loss of firmness while extrinsic aging appears as coarser wrinkles and dark spots.
  • At the heart of both types of aging is cellular senescence, the accumulation of aged cells that trigger skin damage.
  • Extrinsic aging can be prevented by wearing sunscreen, eating healthy, and avoiding cigarettes
  • The OS-01 peptide has the potential to improve overall skin health by preventing intrinsic aging caused by the accumulation of senescent cells (shown in in vitro skin cultures from patient derived samples).

References:

  1. https://platinumdermatology.com.au/articles/extrinsic-vs-intrinsic-ageing-whats-the-difference/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047276
  3. https://platinumdermatology.com.au/articles/extrinsic-vs-intrinsic-ageing-whats-the-difference/
  4. https://biopelle.com/latest-blog-posts/intrinsic-aging-extrinsic-aging-skin/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047276

Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin

Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.

Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin

Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.

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Can Air Quality Affect Skin? Exploring the Impact ...
Close up of eye
Understanding the Relationship Between Sleep and U...
Woman not sleeping in bed
Exploring the Effects of Quality Sleep on Your Ski...
Gut microbiom illustration
How to Improve Gut Microbiome
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Exploring Caloric Restriction and Its Effects on A...
woman stretching in bed
What’s the Connection Between Quality Sleep and Lo...
Healthy foods
Unlocking the Skin Benefits of Intermittent Fastin...
woman exercising
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
The Microbiome Diet and Its Effects on Skin
cold water
Cold Exposure: Hype or Longevity Boosting?
healthy foods
Eat Better, Live Longer: Top Foods for Longevity
How Environmental Stressors Affect Skin
How to Protect Your Skin from Everyday Environment...
Gut Health and Skin: How Are They Connected?
OS-01 BODY
Pressing the Pause Button on Aging Skin: OS-01 BOD...
lip treatment
Lip Balm Ingredients: What to Look for and What to...
earth
Exploring Blue Zones: How Can We Optimize Our Heal...
Sunburn
Sun Exposure and Your Skin: 6 Things You Need to K...
Lips
Nurturing Your Lips: How to Keep Them Moisturized ...
Lips
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care
How to Travel with Skin Care Products
SHIELD on arm
What is The Difference Between UVA and UVB Rays?
SHIELD on arm
The Importance of Sunscreen: Why Should You Wear I...
Lip sunscreen
Lip Sunscreen: Do Lips Need SPF Protection?
heart hands
The Science of Gratitude
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Removing Sunscreen: Tips for Clean and Healthy Ski...
freckled skin
Skin Explained: Is Skin An Organ?
UV Light and Skin
UV Light and Skin: Effects and Protection Strategi...
What is Epidermis
Understanding The Epidermis: Functions, Compositio...
Diving into dermis
Diving into Dermis: Functions and Significance
Why Do We Get Wrinkles
Unlocking the Science of Wrinkles: Causes, Formati...
bentonite clay
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Back skin
Why Skin Barrier is Important
hypodermis function
Hypodermis: Exploring Its Vital Functions
oil-dropper-background-pink-dripping-cosmetic-product
The EU is Limiting Retinol in Skincare: Here’s Eve...
face+shield
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage
The Lip Lineage: Exploring the Why Behind Wrinkled...
A Journey Through the Skin: How UV Radiation Cause...
How to Address Stomach Wrinkles
How to Address Stomach Wrinkles For Smoother Skin
How to Get Rid of Wrinkly Skin on Arms
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
How Do Our Products Work Together?
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
What is Tinted Sunscreen?
two types of face wrinkles
2 Types of Wrinkles and Tips for Treating Them
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The Top 5 Benefits of Zinc Oxide for Skin
Marionette Lines
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
This is the Data to Look For When Choosing Skin Ca...
This is the Data to Look For When Choosing Skin Ca...
how-much-sunscreen-to-use-on-face
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
Benefits of Sunscreen
Beyond UV Protection: 7 Surprising Ways Sunscreen ...
Mineral vs Chemical Sunscreen
Making Sense of Sunscreen: Understanding the Diffe...
Navigating Anti-Aging Skincare: The industry, the ...
Sun spots
Sun Spots: Causes & 3 Prevention Tips
sunscreen-ingredients-to-avoid
Navigating Sunscreen Labels: Unwanted Ingredients ...
How to Prevent Skin Aging Before It Starts
Face vs. Body Sunscreen: Can You Use Body Sunscreen On Your Face?
Face vs. Body Sunscreen: Can You Use Body Sunscree...
Sun Damaged Skin: What it is, how you can prevent ...
Thick Skin vs Thin Skin
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin
How to Strengthen Your Skin: A Guide to Thicker, H...
what-is-glycerin
An In-Depth Look at Glycerin: What is it and What ...
Difference Between Hydrating and Moisturizing
Exploring the Difference Between Hydrating and Moi...
Difference Between Hydrating and Moisturizing
Exploring the Difference Between Hydrating and Moi...
Glycerin Benefits for Skin
Exploring the Benefits of Glycerin for Skin Health
Keep Your Skin Hydrated
3 Natural Ways to Keep Your Skin Hydrated and Glow...
Keep Your Skin Hydrated
3 Natural Ways to Keep Your Skin Hydrated and Glow...
Hydrating Skin Care Routine For Dry Skin
How To Create A Hydrating Skin Care Routine For Dr...
Hydrating Skin Care Routine For Dry Skin
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
How OS-01 Can Help Your Collagen Levels As You Age
How OS-01 Can Help Your Collagen Levels As You Age...
4 Essential Face Cleansing Steps to Achieving a Ra...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
Moved - What is Normal Skin & Do I Have This Skin ...
Skin Care Routine for Oily Skin
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
Menopause and Skin Changes
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
What Do Antioxidants Do For Skin and Why Should You Care?
What Do Antioxidants Do For Skin and Why Should Yo...
Perfect Skin Care Routine for Combination Skin
4 Steps to Crafting the Perfect Skin Care Routine ...
Managing Combination Skin
A Comprehensive Guide to Understanding and Managin...
Benefits Of Moringa Oil
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
How to Tighten the Skin Under Your Eyes
Restoring Dry Skin Around The Eyes
101 Guide To Restoring Dry Skin Around The Eyes Mo...
7 Causes For Crepey Skin Under Eyes
Restoring Dry Skin Around The Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
Woman washing her face
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
What is Epidermal Thickness & Why Does it Matter?
Hallmarks Of Aging - One Skin Technologies
Hallmarks of Aging
What Is Sensitive Skin
What is Sensitive Skin?
Cell Turnover & Why It Slows As We Age
How to Reduce Skin Inflammation
How to Reduce Skin Inflammation & Redness
101 Guide To Skin Tightening
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin
Tight Feeling Skin: 3 Reasons Why
Skin Tightening Ingredients
3 Skin Tightening Ingredients To Help Boost Skin H...
How OS-01 Works on Mature Skin
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin
Is Fragrance Bad for Your Skin?
Are Parabens Bad for Your Skin
Are Parabens Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
The Science Behind Why The Skin Around the Eyes Ag...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
6 Factors That Contribute to Slow Skin Healing
4 Foods To Avoid During Wound Healing & Why
A Complete Guide to the 4 Stages of Wound Healing
Collagen And Elastin: What Role Do They Play In Sk...
How to Repair & Restore Your Skin Barrier
How to Repair & Restore Your Skin Barrier
How to Know if Your Skin Barrier is Damaged
What is the Function of Skin as a Protective Barrier
What is the Function of Skin as a Protective Barri...
Why We Want Skin To Be More, Not Less
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Decoding the Connections Between Intrinsic & Extri...
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
When to Apply Sunscreen: Before or After Moisturizer
When to Apply Sunscreen: Before or After Moisturiz...
Stressed Skin
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
How Does Sunscreen Work? How Long Does it Last?
How Does Sunscreen Work? How Long Does it Last?
What is the Best Skin Care Regimen for Aging Skin
What is the Best Skin Care Regimen for Aging Skin?
What happens to skin as a person ages?
What Causes Dark Circles Under and Around Your Eyes?
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Invasive vs. Non-Invasive Skincare: The pros and c...
6 Benefits of Jojoba Oil
6 Benefits of Jojoba Oil
What are the Benefits of Sulforaphane?
What are the Benefits of Sulforaphane?
What is Sustainable Packaging for Cosmetic Products?
What is Sustainable Packaging for Cosmetic Product...
7 Benefits of Andiroba Oil For Skin
Why is my Skin Peeling on My Face?
What Are The Causes Of Dry, Flaky Skin On Your Fac...
PREP enhances the effects of OS-01 FACE, and the p...
Why cellular senescence is more than just one of t...
Allantoin For Skin: A Comprehensive Guide
Ceramides For Skin: Everything You Need to Know
A Simplified Guide To The Different Skin Texture Types
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
How To Get Rid of Crepey Skin: 7 Solutions
What Causes Crepey Skin & Can It Be Avoided Altoge...
Does Niacinamide Help With Acne & Scarring?
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure For Long-Term Skin Health?
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide on The Benefits of Cleansing Your Face
How OneSkin Developed the OS-01 Peptide
a smiling woman washing her face
Cleanser Vs. Face Wash: Which Should I Reach For?
5 Common Perimenopause Skin Problems
Five Common Skin Problems Experienced in Perimenop...
You’re only as old as you feel, scientists are fin...
Collagen For Menopause: Why Is It Necessary For Healthy Skin Aging?
Collagen For Menopause: Why Is It Necessary For He...
Get to Know OneSkin’s Topical Supplements:

OS-

...
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Optimize Your Health
How to Use Peptides In Your Skincare Regimen to Op...
peptide illustration
Peptides vs Retinol: Is One Better For Increasing ...
body skin
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Your Body Care Routine
Three Ways To Extend Your Skinspan Starting With Y...
free radicals
What Are Free Radicals and How Do They Impact Skin...
The Connection Between Mental Health, Age Percepti...
The Top 6 Best Antioxidants For Skin Health and Lo...
Zombie Cells
What are Zombie Cells & How Can We Remove Them?
SKIN CARE IS HEALTH CARE: WHY EXTENDING YOUR SKINS...
How chronic stress makes you age faster
OneSkin Notable Mention: OneSkin Featured In Tony ...
Niacinamide
Niacinamide Vs Retinol: How Do They Compare?
What Is Causing the Uneven Skin Tone On Your Body?
illustration of nutrients being absorb
Why Is Nutrient Absorption Key To Better Skin Heal...
Dr. David Sinclair
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
skin repairing foods
The Top 10 Best Foods for Skin Repair
Closeup of a sun spot
Skin Hyperpigmentation 101: What It Is & How To Tr...
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
closeup portrait of a model
Celebrating Black History Month: A Discussion With...
closeup portrait of a model
Celebrating Black History Month: A Discussion With...
Representation of the Black Community in Skin Care and Longevity
Representation of the Black Community in Skin Care...
Portrait of OneSkin Founders
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Where Skin Health Meets Longevity
Health Is The New Wealth - One Skin Technologies
Health Is The New Wealth
Sleep: Nature’s Restart Button? - One Skin Technologies
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
OneSkin launches MolClock, the first skin-specific molecular clock to determine the biological age of human skin - One Skin Technologies
OneSkin launches MolClock, the first skin-specific...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging - One Skin Technologies
Healthspan: A New Way To Think About Aging