OS-01 BODY Topical Supplement
OS-01 BODY Topical Supplement
OS-01 BODY is a restorative skin longevity treatment powered by the OS-01 Senescence Blocking Peptide™, designed to strengthen the skin barrier, improve hydration, and promote firm, resilient skin from the neck down.01
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BENEFITS
Nourishing body moisturizer and targeted treatment for thin, crepey skin
Smooth texture
Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01
Deep hydration
Replenishes and locks in hydration to keep skin soft, plump, and nourished.01
Barrier support
Fortifies the skin barrier to protect against daily stressors and moisture loss.01
5-STAR REVIEWS
See why customers love OS-01 BODY
“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.
"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.
"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
93
of participants reported improved hydration 01
72
of participants reported improved appearance 01
70
of participants reported improved texture 01
41
Improvement in skin barrier function was measured 01
The Science Behind OS-01 BODY
Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.
To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.01
Shown in lab studies on ex vivo human skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.
5 active ingredients complement the OS-01 peptide
Getting started with OS-01 BODY
Follow these easy steps for optimal results
- Apply to arms, legs, chest, back, and stomach
- Massage until absorbed
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.02,03
All Ingredients
Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide
Citations
01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
OS-01 BODY Topical Supplement
- SCSue C.Verified BuyerReviewingOS-01 BODY Topical SupplementI recommend this productRated 5 out of 5 stars4 minutes agoLove this
This is the best hydrating lotions I’ve ever used. I can get itchy skin and have tried numerous lotions. Most are more creamy and I feel like they leave some type of heavy cream that makes me more itchy. This is hydrating and makes your sling feel incredible without feeling it has a layer of film on it. Just clean and fresh. Price point is not the best for the size of the bottle but it is the real deal as far as what it does!
- CSCarolyn S.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 stars11 hours agoI’ve been suffering from severe atopic dermatitis with eczema all over my body. Started biologic treatment and skin has calmed. So trying new products that won’t create flareups. Hesitant at first applying only to small portion of inner leg and arm. No problems!! Product is concentrated.
Great on sensitive skin!!
- STSusan T.Verified BuyerReviewingReplacement OS-01 BODYI recommend this productRated 5 out of 5 stars12 hours agoMy softer skin
My 74 year old skin lives in the dry climate of Southern California. I’ve tried several different lotions, creams, crepe removers but this is the 1st lotion that really made a difference.
- ADAmy D.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 stars12 hours agoAmazing!!
I love One Skin OS-01 Body Lotion. I've never had these kind of results with a lotion....ever. And believe me, I've tried them ALL!!! I'm about to turn 50 and have noticed in the past couple years that my skin is staring to show it's age. After the first week, I could see and mostly feel a big improvement. The price...yes...the price is a bit steep. But a little goes a long way. No harsh smells or crazy perfumes. I love it and my skin loves it!!
- LCLynne C.Verified BuyerReviewingOS-01 BODYI recommend this productRated 5 out of 5 starsYesterdayUse this product daily.
Really notice the difference in my skin if I forget to apply it to my shoulders. I notice reduction in loose skin so I guess it feels as well looks tighter.
